Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry
<p dir="ltr">The rise of antibiotic-resistant <i>Salmonella</i> in poultry poses a significant public health challenge. This study assessed the efficacy of carvacrol and trans-cinnamaldehyde, in free and nanoencapsulated forms, as natural alternatives to chlorine for inac...
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| مؤلفون آخرون: | , , , , , |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
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| _version_ | 1864513525499559936 |
|---|---|
| author | Samah Mechmechani (12988420) |
| author2 | Kosar Zadeh (22928896) Neda Zadeh (12869225) Adem Gharsallaoui (12988423) Nahla O. Eltai (9291053) Tareq M. Osaili (9324412) Layal Karam (17019102) |
| author2_role | author author author author author author |
| author_facet | Samah Mechmechani (12988420) Kosar Zadeh (22928896) Neda Zadeh (12869225) Adem Gharsallaoui (12988423) Nahla O. Eltai (9291053) Tareq M. Osaili (9324412) Layal Karam (17019102) |
| author_role | author |
| dc.creator.none.fl_str_mv | Samah Mechmechani (12988420) Kosar Zadeh (22928896) Neda Zadeh (12869225) Adem Gharsallaoui (12988423) Nahla O. Eltai (9291053) Tareq M. Osaili (9324412) Layal Karam (17019102) |
| dc.date.none.fl_str_mv | 2025-08-14T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s00253-025-13573-4 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Advanced_monolayer_and_layer-by-layer_nanocapsule_systems_for_sustained_release_of_carvacrol_and_trans-cinnamaldehyde_against_multidrug-resistant_i_Salmonella_i_in_poultry/30971665 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Agricultural, veterinary and food sciences Food sciences Environmental sciences Environmental biotechnology Health sciences Public health Poultry Nanoencapsulation Monolayer Layer-by-layer Antimicrobial activity Antimicrobial resistance |
| dc.title.none.fl_str_mv | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">The rise of antibiotic-resistant <i>Salmonella</i> in poultry poses a significant public health challenge. This study assessed the efficacy of carvacrol and trans-cinnamaldehyde, in free and nanoencapsulated forms, as natural alternatives to chlorine for inactivating antibiotic-resistant <i>Salmonella</i> in chicken. While several studies have evaluated free trans-cinnamaldehyde and carvacrol, there is a notable lack of research on encapsulated forms, using different types of capsules for controlled release of these antimicrobials in food applications. Both compounds were encapsulated by spray-drying into monolayer nanocapsules using maltodextrin as the carrier material, and into layer-by-layer nanocapsules with an additional layer of low methoxyl pectin, to enhance their stability and prolong antimicrobial activity. Twelve treatment groups were evaluated, including controls (distilled water), chlorine (50 ppm), and various concentrations of carvacrol and <i>trans</i>-cinnamaldehyde in their free or nanoencapsulated forms. The combination of monolayer and layer-by-layer carvacrol nanocapsules at a total concentration of 4% resulted in the highest <i>Salmonella</i> reduction (3.7 log CFU/g) after 11 days, significantly outperforming all other treatments (<i>p</i> < 0.05). Trans-cinnamaldehyde-based treatments, whether free or encapsulated forms, demonstrated delayed but notable reductions (2.0–2.2 log CFU/g), followed by carvacrol treatments at 2% using layer-by-layer nanocapsules alone or in combination with monolayer nanocapsules (1.5 log CFU/g). Free or monolayer carvacrol at 2% achieved reductions of 1.1–1.3 log CFU/g, while chlorine (50 ppm) was the least effective, with a reduction of 0.9 log CFU/g. These findings underscore the potential of nanoencapsulated carvacrol and <i>trans</i>-cinnamaldehyde as sustainable, eco-friendly, and effective solutions for enhancing poultry safety, mitigating antimicrobial resistance, and meeting consumer preferences for natural food preservation.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Applied Microbiology and Biotechnology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00253-025-13573-4" target="_blank">https://dx.doi.org/10.1007/s00253-025-13573-4</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_6cbb29d653ed59f7a4c1aac448ffd8d8 |
| identifier_str_mv | 10.1007/s00253-025-13573-4 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30971665 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultrySamah Mechmechani (12988420)Kosar Zadeh (22928896)Neda Zadeh (12869225)Adem Gharsallaoui (12988423)Nahla O. Eltai (9291053)Tareq M. Osaili (9324412)Layal Karam (17019102)Agricultural, veterinary and food sciencesFood sciencesEnvironmental sciencesEnvironmental biotechnologyHealth sciencesPublic healthPoultryNanoencapsulationMonolayerLayer-by-layerAntimicrobial activityAntimicrobial resistance<p dir="ltr">The rise of antibiotic-resistant <i>Salmonella</i> in poultry poses a significant public health challenge. This study assessed the efficacy of carvacrol and trans-cinnamaldehyde, in free and nanoencapsulated forms, as natural alternatives to chlorine for inactivating antibiotic-resistant <i>Salmonella</i> in chicken. While several studies have evaluated free trans-cinnamaldehyde and carvacrol, there is a notable lack of research on encapsulated forms, using different types of capsules for controlled release of these antimicrobials in food applications. Both compounds were encapsulated by spray-drying into monolayer nanocapsules using maltodextrin as the carrier material, and into layer-by-layer nanocapsules with an additional layer of low methoxyl pectin, to enhance their stability and prolong antimicrobial activity. Twelve treatment groups were evaluated, including controls (distilled water), chlorine (50 ppm), and various concentrations of carvacrol and <i>trans</i>-cinnamaldehyde in their free or nanoencapsulated forms. The combination of monolayer and layer-by-layer carvacrol nanocapsules at a total concentration of 4% resulted in the highest <i>Salmonella</i> reduction (3.7 log CFU/g) after 11 days, significantly outperforming all other treatments (<i>p</i> < 0.05). Trans-cinnamaldehyde-based treatments, whether free or encapsulated forms, demonstrated delayed but notable reductions (2.0–2.2 log CFU/g), followed by carvacrol treatments at 2% using layer-by-layer nanocapsules alone or in combination with monolayer nanocapsules (1.5 log CFU/g). Free or monolayer carvacrol at 2% achieved reductions of 1.1–1.3 log CFU/g, while chlorine (50 ppm) was the least effective, with a reduction of 0.9 log CFU/g. These findings underscore the potential of nanoencapsulated carvacrol and <i>trans</i>-cinnamaldehyde as sustainable, eco-friendly, and effective solutions for enhancing poultry safety, mitigating antimicrobial resistance, and meeting consumer preferences for natural food preservation.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Applied Microbiology and Biotechnology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00253-025-13573-4" target="_blank">https://dx.doi.org/10.1007/s00253-025-13573-4</a></p>2025-08-14T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s00253-025-13573-4https://figshare.com/articles/journal_contribution/Advanced_monolayer_and_layer-by-layer_nanocapsule_systems_for_sustained_release_of_carvacrol_and_trans-cinnamaldehyde_against_multidrug-resistant_i_Salmonella_i_in_poultry/30971665CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/309716652025-08-14T09:00:00Z |
| spellingShingle | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry Samah Mechmechani (12988420) Agricultural, veterinary and food sciences Food sciences Environmental sciences Environmental biotechnology Health sciences Public health Poultry Nanoencapsulation Monolayer Layer-by-layer Antimicrobial activity Antimicrobial resistance |
| status_str | publishedVersion |
| title | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| title_full | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| title_fullStr | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| title_full_unstemmed | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| title_short | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| title_sort | Advanced monolayer and layer-by-layer nanocapsule systems for sustained release of carvacrol and trans-cinnamaldehyde against multidrug-resistant <i>Salmonella</i> in poultry |
| topic | Agricultural, veterinary and food sciences Food sciences Environmental sciences Environmental biotechnology Health sciences Public health Poultry Nanoencapsulation Monolayer Layer-by-layer Antimicrobial activity Antimicrobial resistance |