Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis
<h3>Background</h3><p dir="ltr">Post-traumatic stress disorder (PTSD) is increasingly recognized for its effects beyond mental health, with emerging evidence suggesting a significant association with cardiovascular diseases (CVD). This <u>systematic review</u>...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513542155141120 |
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| author | Bijaya K Padhi (16823745) |
| author2 | Mahalaqua Nazli Khatib (9714860) Hashem Abu Serhan (15993651) Abhay M Gaidhane (17910632) Sarvesh Rustagi (17471712) Quazi Syed Zahiruddin (13231791) Rakesh Kumar Sharma (7271042) Prakasini Satapathy (8677284) |
| author2_role | author author author author author author author |
| author_facet | Bijaya K Padhi (16823745) Mahalaqua Nazli Khatib (9714860) Hashem Abu Serhan (15993651) Abhay M Gaidhane (17910632) Sarvesh Rustagi (17471712) Quazi Syed Zahiruddin (13231791) Rakesh Kumar Sharma (7271042) Prakasini Satapathy (8677284) |
| author_role | author |
| dc.creator.none.fl_str_mv | Bijaya K Padhi (16823745) Mahalaqua Nazli Khatib (9714860) Hashem Abu Serhan (15993651) Abhay M Gaidhane (17910632) Sarvesh Rustagi (17471712) Quazi Syed Zahiruddin (13231791) Rakesh Kumar Sharma (7271042) Prakasini Satapathy (8677284) |
| dc.date.none.fl_str_mv | 2024-05-29T12:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.cpcardiol.2024.102632 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Cardiovascular_impact_of_post-traumatic_stress_disorder_A_systematic_review_and_meta-analysis/29715764 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Health sciences Public health Post-traumatic stress disorder Stroke Myocardial infarction Meta-analysis Public health |
| dc.title.none.fl_str_mv | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Post-traumatic stress disorder (PTSD) is increasingly recognized for its effects beyond mental health, with emerging evidence suggesting a significant association with cardiovascular diseases (CVD). This <u>systematic review</u> and meta-analysis aimed to synthesize available evidence on the association between PTSD and various cardiovascular outcomes. </p><h3>Methods</h3><p dir="ltr">We conducted a comprehensive literature search in databases until March 15, 2024. Studies were included if they were observational in design and assessed the association between PTSD and cardiovascular outcomes. Data were extracted on study characteristics, participant demographics, PTSD assessment, cardiovascular outcomes, and effect estimates. Meta-analyses were performed using random-effects models, and heterogeneity was assessed using the I² statistic. All statistical analyses were conducted using R software version 4.3. </p><h3>Results</h3><p dir="ltr">Twenty studies met the inclusion criteria, encompassing a total of over 335,000 participants. The pooled analyses demonstrated a statistically significant increased risk of any CVD (HR = 1.417, 95 % CI: 1.313-1.522), MI (HR = 1.415, 95 % CI: 1.331-1.500), and stroke (HR = 2.074, 95 % CI: 1.165-2.982) associated with PTSD. Substantial heterogeneity was observed across the studies for stroke and MACE, and evidence of publication bias was noted. </p><h3>Conclusion</h3><p dir="ltr">This meta-analysis confirms a significant association between PTSD and an increased risk of several cardiovascular outcomes, indicating the importance of integrating cardiovascular risk management with psychiatric care for PTSD patients to mitigate the heightened risk of CVDs. Future research should focus on exploring the underlying mechanisms and potential interventions to manage both PTSD and its associated cardiovascular risks effectively.</p><h2>Other Information</h2><p dir="ltr">Published in: Current Problems in Cardiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cpcardiol.2024.102632" target="_blank">https://dx.doi.org/10.1016/j.cpcardiol.2024.102632</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_6de2f720a8bb97ee143882d024227d04 |
| identifier_str_mv | 10.1016/j.cpcardiol.2024.102632 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29715764 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysisBijaya K Padhi (16823745)Mahalaqua Nazli Khatib (9714860)Hashem Abu Serhan (15993651)Abhay M Gaidhane (17910632)Sarvesh Rustagi (17471712)Quazi Syed Zahiruddin (13231791)Rakesh Kumar Sharma (7271042)Prakasini Satapathy (8677284)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesHealth sciencesPublic healthPost-traumatic stress disorderStrokeMyocardial infarctionMeta-analysisPublic health<h3>Background</h3><p dir="ltr">Post-traumatic stress disorder (PTSD) is increasingly recognized for its effects beyond mental health, with emerging evidence suggesting a significant association with cardiovascular diseases (CVD). This <u>systematic review</u> and meta-analysis aimed to synthesize available evidence on the association between PTSD and various cardiovascular outcomes. </p><h3>Methods</h3><p dir="ltr">We conducted a comprehensive literature search in databases until March 15, 2024. Studies were included if they were observational in design and assessed the association between PTSD and cardiovascular outcomes. Data were extracted on study characteristics, participant demographics, PTSD assessment, cardiovascular outcomes, and effect estimates. Meta-analyses were performed using random-effects models, and heterogeneity was assessed using the I² statistic. All statistical analyses were conducted using R software version 4.3. </p><h3>Results</h3><p dir="ltr">Twenty studies met the inclusion criteria, encompassing a total of over 335,000 participants. The pooled analyses demonstrated a statistically significant increased risk of any CVD (HR = 1.417, 95 % CI: 1.313-1.522), MI (HR = 1.415, 95 % CI: 1.331-1.500), and stroke (HR = 2.074, 95 % CI: 1.165-2.982) associated with PTSD. Substantial heterogeneity was observed across the studies for stroke and MACE, and evidence of publication bias was noted. </p><h3>Conclusion</h3><p dir="ltr">This meta-analysis confirms a significant association between PTSD and an increased risk of several cardiovascular outcomes, indicating the importance of integrating cardiovascular risk management with psychiatric care for PTSD patients to mitigate the heightened risk of CVDs. Future research should focus on exploring the underlying mechanisms and potential interventions to manage both PTSD and its associated cardiovascular risks effectively.</p><h2>Other Information</h2><p dir="ltr">Published in: Current Problems in Cardiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cpcardiol.2024.102632" target="_blank">https://dx.doi.org/10.1016/j.cpcardiol.2024.102632</a></p>2024-05-29T12:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.cpcardiol.2024.102632https://figshare.com/articles/journal_contribution/Cardiovascular_impact_of_post-traumatic_stress_disorder_A_systematic_review_and_meta-analysis/29715764CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297157642024-05-29T12:00:00Z |
| spellingShingle | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis Bijaya K Padhi (16823745) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Health sciences Public health Post-traumatic stress disorder Stroke Myocardial infarction Meta-analysis Public health |
| status_str | publishedVersion |
| title | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| title_full | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| title_fullStr | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| title_full_unstemmed | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| title_short | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| title_sort | Cardiovascular impact of post-traumatic stress disorder: A systematic review and meta-analysis |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Health sciences Public health Post-traumatic stress disorder Stroke Myocardial infarction Meta-analysis Public health |