Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?

<h3 dir="ltr">Background</h3><p dir="ltr">DeepSeek is a recently launched large language model (LLM), whereas GPT-4o is an advanced ChatGPT version whose electrocardiography (ECG) interpretation capabilities have been previously studied. However, DeepSeek’s perf...

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Main Author: Serkan GÜNAY (23072548) (author)
Other Authors: Ahmet ÖZTÜRK (23072551) (author), Anılcan Tahsin KARAHAN (23072554) (author), Mert BARINDIK (23072557) (author), Seval KOMUT (23072560) (author), Yavuz YİĞİT (23072563) (author)
Published: 2025
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author Serkan GÜNAY (23072548)
author2 Ahmet ÖZTÜRK (23072551)
Anılcan Tahsin KARAHAN (23072554)
Mert BARINDIK (23072557)
Seval KOMUT (23072560)
Yavuz YİĞİT (23072563)
author2_role author
author
author
author
author
author_facet Serkan GÜNAY (23072548)
Ahmet ÖZTÜRK (23072551)
Anılcan Tahsin KARAHAN (23072554)
Mert BARINDIK (23072557)
Seval KOMUT (23072560)
Yavuz YİĞİT (23072563)
author_role author
dc.creator.none.fl_str_mv Serkan GÜNAY (23072548)
Ahmet ÖZTÜRK (23072551)
Anılcan Tahsin KARAHAN (23072554)
Mert BARINDIK (23072557)
Seval KOMUT (23072560)
Yavuz YİĞİT (23072563)
dc.date.none.fl_str_mv 2025-11-14T12:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.hrtlng.2025.08.007
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Comparing_DeepSeek_and_GPT-4o_in_ECG_interpretation_Is_AI_improving_over_time_/31167910
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
ChatGPT
GPT-4o
Deep
Seek
Electrocardiography
Emergency medicine
dc.title.none.fl_str_mv Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3 dir="ltr">Background</h3><p dir="ltr">DeepSeek is a recently launched large language model (LLM), whereas GPT-4o is an advanced ChatGPT version whose electrocardiography (ECG) interpretation capabilities have been previously studied. However, DeepSeek’s performance in this domain remains unexplored. </p><h3 dir="ltr">Objectives</h3><p dir="ltr">This study aims to evaluate DeepSeek’s accuracy in ECG interpretation and compare it with GPT-4o, emergency medicine specialists, and cardiologists. A secondary aim is to assess any performance changes in GPT-4o over one year. </p><h3 dir="ltr">Methods</h3><p dir="ltr">Between February 9 and March 1, 2025, 40 ECG images (20 daily routine, 20 more challenging) from the book 150 ECG Cases were evaluated by both GPT-4o and DeepSeek, each model tested 13 times. The accuracy of their responses was compared with previously collected answers from 12 cardiologists and 12 emergency medicine specialists. GPT-4o’s 2025 performance was compared to its 2024 results on identical ECGs. </p><h3 dir="ltr">Results</h3><p dir="ltr">GPT-4o outperformed DeepSeek with higher median correct answers on daily routine (14 vs. 12), more challenging (13 vs. 10), and total ECGs (27 vs. 22) with statistically significant differences (p=0.048, p<0.001, p<0.001). A moderate agreement was observed between the responses provided by GPT-4o (p<0.001, Fleiss Kappa=0.473), while a substantial agreement was observed in the responses provided by DeepSeek (p<0.001, Fleiss Kappa=0.712). No significant year-over-year improvement was observed in GPT-4o’s performance. </p><h3 dir="ltr">Conclusion</h3><p dir="ltr">This first evaluation of DeepSeek in ECG interpretation reveals its performance is lower than that of GPT-4o and human experts. While GPT-4o demonstrates greater accuracy, both models fall short of expert-level performance, underscoring the need for caution and further validation before clinical integration.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Heart & Lung<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.hrtlng.2025.08.007" target="_blank">https://dx.doi.org/10.1016/j.hrtlng.2025.08.007</a></p>
eu_rights_str_mv openAccess
id Manara2_6e5e299072878db4a1e39635e588b53a
identifier_str_mv 10.1016/j.hrtlng.2025.08.007
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/31167910
publishDate 2025
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rights_invalid_str_mv CC BY 4.0
spelling Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?Serkan GÜNAY (23072548)Ahmet ÖZTÜRK (23072551)Anılcan Tahsin KARAHAN (23072554)Mert BARINDIK (23072557)Seval KOMUT (23072560)Yavuz YİĞİT (23072563)Biomedical and clinical sciencesCardiovascular medicine and haematologyHealth sciencesHealth services and systemsInformation and computing sciencesArtificial intelligenceChatGPTGPT-4oDeepSeekElectrocardiographyEmergency medicine<h3 dir="ltr">Background</h3><p dir="ltr">DeepSeek is a recently launched large language model (LLM), whereas GPT-4o is an advanced ChatGPT version whose electrocardiography (ECG) interpretation capabilities have been previously studied. However, DeepSeek’s performance in this domain remains unexplored. </p><h3 dir="ltr">Objectives</h3><p dir="ltr">This study aims to evaluate DeepSeek’s accuracy in ECG interpretation and compare it with GPT-4o, emergency medicine specialists, and cardiologists. A secondary aim is to assess any performance changes in GPT-4o over one year. </p><h3 dir="ltr">Methods</h3><p dir="ltr">Between February 9 and March 1, 2025, 40 ECG images (20 daily routine, 20 more challenging) from the book 150 ECG Cases were evaluated by both GPT-4o and DeepSeek, each model tested 13 times. The accuracy of their responses was compared with previously collected answers from 12 cardiologists and 12 emergency medicine specialists. GPT-4o’s 2025 performance was compared to its 2024 results on identical ECGs. </p><h3 dir="ltr">Results</h3><p dir="ltr">GPT-4o outperformed DeepSeek with higher median correct answers on daily routine (14 vs. 12), more challenging (13 vs. 10), and total ECGs (27 vs. 22) with statistically significant differences (p=0.048, p<0.001, p<0.001). A moderate agreement was observed between the responses provided by GPT-4o (p<0.001, Fleiss Kappa=0.473), while a substantial agreement was observed in the responses provided by DeepSeek (p<0.001, Fleiss Kappa=0.712). No significant year-over-year improvement was observed in GPT-4o’s performance. </p><h3 dir="ltr">Conclusion</h3><p dir="ltr">This first evaluation of DeepSeek in ECG interpretation reveals its performance is lower than that of GPT-4o and human experts. While GPT-4o demonstrates greater accuracy, both models fall short of expert-level performance, underscoring the need for caution and further validation before clinical integration.</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Heart & Lung<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.hrtlng.2025.08.007" target="_blank">https://dx.doi.org/10.1016/j.hrtlng.2025.08.007</a></p>2025-11-14T12:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.hrtlng.2025.08.007https://figshare.com/articles/journal_contribution/Comparing_DeepSeek_and_GPT-4o_in_ECG_interpretation_Is_AI_improving_over_time_/31167910CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/311679102025-11-14T12:00:00Z
spellingShingle Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
Serkan GÜNAY (23072548)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
ChatGPT
GPT-4o
Deep
Seek
Electrocardiography
Emergency medicine
status_str publishedVersion
title Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
title_full Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
title_fullStr Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
title_full_unstemmed Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
title_short Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
title_sort Comparing DeepSeek and GPT-4o in ECG interpretation: Is AI improving over time?
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
ChatGPT
GPT-4o
Deep
Seek
Electrocardiography
Emergency medicine