Odor coding in the mammalian olfactory epithelium

<div><p>Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Smija M. Kurian (5180606) (author)
مؤلفون آخرون: Rafaella G. Naressi (18513777) (author), Diogo Manoel (169191) (author), Ann-Sophie Barwich (18513780) (author), Bettina Malnic (190162) (author), Luis R. Saraiva (18282274) (author)
منشور في: 2021
الموضوعات:
الوسوم: إضافة وسم
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author Smija M. Kurian (5180606)
author2 Rafaella G. Naressi (18513777)
Diogo Manoel (169191)
Ann-Sophie Barwich (18513780)
Bettina Malnic (190162)
Luis R. Saraiva (18282274)
author2_role author
author
author
author
author
author_facet Smija M. Kurian (5180606)
Rafaella G. Naressi (18513777)
Diogo Manoel (169191)
Ann-Sophie Barwich (18513780)
Bettina Malnic (190162)
Luis R. Saraiva (18282274)
author_role author
dc.creator.none.fl_str_mv Smija M. Kurian (5180606)
Rafaella G. Naressi (18513777)
Diogo Manoel (169191)
Ann-Sophie Barwich (18513780)
Bettina Malnic (190162)
Luis R. Saraiva (18282274)
dc.date.none.fl_str_mv 2021-01-06T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s00441-020-03327-1
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Odor_coding_in_the_mammalian_olfactory_epithelium/25764873
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Neurosciences
Olfaction
Odor coding
Combinatorial code
Odorant
Receptor
Antagonist
Smell
dc.title.none.fl_str_mv Odor coding in the mammalian olfactory epithelium
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <div><p>Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different concentrations of the same odorant, activate unique ensembles of ORs. This mechanism of combinatorial receptor coding provided a possible explanation as to why different odorants are perceived as having distinct odors. Aided by new technologies, several recent studies have found that antagonist interactions also play an important role in the formation of the combinatorial receptor code. These findings mark the start of a new era in the study of odorant-receptor interactions and add a new level of complexity to odor coding in mammals.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Cell and Tissue Research<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00441-020-03327-1" target="_blank">https://dx.doi.org/10.1007/s00441-020-03327-1</a></p>
eu_rights_str_mv openAccess
id Manara2_6fd44a1e7360b5c1ee5e97f9859ed4b9
identifier_str_mv 10.1007/s00441-020-03327-1
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/25764873
publishDate 2021
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Odor coding in the mammalian olfactory epitheliumSmija M. Kurian (5180606)Rafaella G. Naressi (18513777)Diogo Manoel (169191)Ann-Sophie Barwich (18513780)Bettina Malnic (190162)Luis R. Saraiva (18282274)Biomedical and clinical sciencesNeurosciencesOlfactionOdor codingCombinatorial codeOdorantReceptorAntagonistSmell<div><p>Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different concentrations of the same odorant, activate unique ensembles of ORs. This mechanism of combinatorial receptor coding provided a possible explanation as to why different odorants are perceived as having distinct odors. Aided by new technologies, several recent studies have found that antagonist interactions also play an important role in the formation of the combinatorial receptor code. These findings mark the start of a new era in the study of odorant-receptor interactions and add a new level of complexity to odor coding in mammals.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Cell and Tissue Research<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00441-020-03327-1" target="_blank">https://dx.doi.org/10.1007/s00441-020-03327-1</a></p>2021-01-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s00441-020-03327-1https://figshare.com/articles/journal_contribution/Odor_coding_in_the_mammalian_olfactory_epithelium/25764873CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/257648732021-01-06T03:00:00Z
spellingShingle Odor coding in the mammalian olfactory epithelium
Smija M. Kurian (5180606)
Biomedical and clinical sciences
Neurosciences
Olfaction
Odor coding
Combinatorial code
Odorant
Receptor
Antagonist
Smell
status_str publishedVersion
title Odor coding in the mammalian olfactory epithelium
title_full Odor coding in the mammalian olfactory epithelium
title_fullStr Odor coding in the mammalian olfactory epithelium
title_full_unstemmed Odor coding in the mammalian olfactory epithelium
title_short Odor coding in the mammalian olfactory epithelium
title_sort Odor coding in the mammalian olfactory epithelium
topic Biomedical and clinical sciences
Neurosciences
Olfaction
Odor coding
Combinatorial code
Odorant
Receptor
Antagonist
Smell