Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy
<p dir="ltr">Despite the availability of technological advances in traditional anti-cancer therapies, there is a need for more precise and targeted cancer treatment strategies. The wide-ranging shortfalls of conventional anticancer therapies such as systematic toxicity, compromised l...
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2024
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| _version_ | 1864513518523383808 |
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| author | Aasma Zafar (17785652) |
| author2 | Muhammad Jawad Khan (6909224) Junaid Abu (21633341) Aisha Naeem (14157078) |
| author2_role | author author author |
| author_facet | Aasma Zafar (17785652) Muhammad Jawad Khan (6909224) Junaid Abu (21633341) Aisha Naeem (14157078) |
| author_role | author |
| dc.creator.none.fl_str_mv | Aasma Zafar (17785652) Muhammad Jawad Khan (6909224) Junaid Abu (21633341) Aisha Naeem (14157078) |
| dc.date.none.fl_str_mv | 2024-01-28T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s11033-023-09096-8 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Revolutionizing_cancer_care_strategies_immunotherapy_gene_therapy_and_molecular_targeted_therapy/29445917 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Genetics Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences Immunotherapy Gene therapy Targeted molecular therapy |
| dc.title.none.fl_str_mv | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Despite the availability of technological advances in traditional anti-cancer therapies, there is a need for more precise and targeted cancer treatment strategies. The wide-ranging shortfalls of conventional anticancer therapies such as systematic toxicity, compromised life quality, and limited to severe side effects are major areas of concern of conventional cancer treatment approaches. Owing to the expansion of knowledge and technological advancements in the field of cancer biology, more innovative and safe anti-cancerous approaches such as immune therapy, gene therapy and targeted therapy are rapidly evolving with the aim to address the limitations of conventional therapies. The concept of immunotherapy began with the capability of coley toxins to stimulate toll-like receptors of immune cells to provoke an immune response against cancers. With an in-depth understating of the molecular mechanisms of carcinogenesis and their relationship to disease prognosis, molecular targeted therapy approaches, that inhibit or stimulate specific cancer-promoting or cancer-inhibitory molecules respectively, have offered promising outcomes. In this review, we evaluate the achievement and challenges of these technically advanced therapies with the aim of presenting the overall progress and perspective of each approach.</p><h2>Other Information</h2><p dir="ltr">Published in: Molecular Biology Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11033-023-09096-8" target="_blank">https://dx.doi.org/10.1007/s11033-023-09096-8</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_71b668b4d54e14253ec8f21f159d7b6e |
| identifier_str_mv | 10.1007/s11033-023-09096-8 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29445917 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapyAasma Zafar (17785652)Muhammad Jawad Khan (6909224)Junaid Abu (21633341)Aisha Naeem (14157078)Biological sciencesGeneticsBiomedical and clinical sciencesOncology and carcinogenesisPharmacology and pharmaceutical sciencesImmunotherapyGene therapyTargeted molecular therapy<p dir="ltr">Despite the availability of technological advances in traditional anti-cancer therapies, there is a need for more precise and targeted cancer treatment strategies. The wide-ranging shortfalls of conventional anticancer therapies such as systematic toxicity, compromised life quality, and limited to severe side effects are major areas of concern of conventional cancer treatment approaches. Owing to the expansion of knowledge and technological advancements in the field of cancer biology, more innovative and safe anti-cancerous approaches such as immune therapy, gene therapy and targeted therapy are rapidly evolving with the aim to address the limitations of conventional therapies. The concept of immunotherapy began with the capability of coley toxins to stimulate toll-like receptors of immune cells to provoke an immune response against cancers. With an in-depth understating of the molecular mechanisms of carcinogenesis and their relationship to disease prognosis, molecular targeted therapy approaches, that inhibit or stimulate specific cancer-promoting or cancer-inhibitory molecules respectively, have offered promising outcomes. In this review, we evaluate the achievement and challenges of these technically advanced therapies with the aim of presenting the overall progress and perspective of each approach.</p><h2>Other Information</h2><p dir="ltr">Published in: Molecular Biology Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11033-023-09096-8" target="_blank">https://dx.doi.org/10.1007/s11033-023-09096-8</a></p>2024-01-28T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11033-023-09096-8https://figshare.com/articles/journal_contribution/Revolutionizing_cancer_care_strategies_immunotherapy_gene_therapy_and_molecular_targeted_therapy/29445917CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/294459172024-01-28T09:00:00Z |
| spellingShingle | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy Aasma Zafar (17785652) Biological sciences Genetics Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences Immunotherapy Gene therapy Targeted molecular therapy |
| status_str | publishedVersion |
| title | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| title_full | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| title_fullStr | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| title_full_unstemmed | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| title_short | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| title_sort | Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy |
| topic | Biological sciences Genetics Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences Immunotherapy Gene therapy Targeted molecular therapy |