Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.</p><h3>Methods</h3><p dir="ltr">This retrospective study aimed to review our institutional...
محفوظ في:
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| مؤلفون آخرون: | , , , , , , , |
| منشور في: |
2024
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إضافة وسم
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| _version_ | 1864513555984809984 |
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| author | Yousef Yahia (19756989) |
| author2 | Ethar Mohamed (19756992) Muniba Afzal (17734044) Azza Ahmed (8525268) Paul Kurian Vincent (19756995) Ma'mon Qasem (19756998) Husam Saffo (19757001) Prem Chandra (9072038) Antony Raphel Joy (19757004) |
| author2_role | author author author author author author author author |
| author_facet | Yousef Yahia (19756989) Ethar Mohamed (19756992) Muniba Afzal (17734044) Azza Ahmed (8525268) Paul Kurian Vincent (19756995) Ma'mon Qasem (19756998) Husam Saffo (19757001) Prem Chandra (9072038) Antony Raphel Joy (19757004) |
| author_role | author |
| dc.creator.none.fl_str_mv | Yousef Yahia (19756989) Ethar Mohamed (19756992) Muniba Afzal (17734044) Azza Ahmed (8525268) Paul Kurian Vincent (19756995) Ma'mon Qasem (19756998) Husam Saffo (19757001) Prem Chandra (9072038) Antony Raphel Joy (19757004) |
| dc.date.none.fl_str_mv | 2024-09-10T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.cpsurg.2024.101626 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Mirizzi_Syndrome_Mastering_the_Challenge_Characterization_and_Management_Outcomes_in_a_Retrospective_Study_of_60_Cases/27130077 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Mirizzi syndrome Gallstone disease Endoscopic Retrograde Cholangiopancreatography Surgical outcomes Laparoscopic cholecystectomy Cholangitis Preoperative diagnosis |
| dc.title.none.fl_str_mv | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.</p><h3>Methods</h3><p dir="ltr">This retrospective study aimed to review our institutional experience in diagnosing and managing MS over seven years and four months.</p><h3>Results</h3><p dir="ltr">Among 8200 cholecystectomies, 60 cases of MS were identified, with type 1 being the most prevalent (90%). The mean age of the patients was 44 years, with male predominance (75%). Southeast Asians comprised 56.7% of the study population. The most common presenting symptom was right upper quadrant pain, and 58.3% of the patients were diagnosed with acute cholangitis. Liver enzyme and bilirubin levels were significantly higher in the advanced types. Preoperative diagnosis was achieved in 70% of patients, with MRCP and ERCP being the most effective diagnostic tools. Laparoscopic cholecystectomy was the most common surgical approach (76.7%), particularly in type 1 (79.6%), and decreased to 50% in advanced types. Hepaticojejunostomy was more common in the advanced types.</p><h3>Conclusion</h3><p dir="ltr">This study highlights the importance of early diagnosis and appropriate management of MS considering its rarity and potential complications. The laparoscopic approach is reasonable, especially for type 1 MS and noncomplicated cases. Further research is needed to optimize treatment strategies for this challenging condition.</p><h2>Other Information</h2><p dir="ltr">Published in: Current Problems in Surgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cpsurg.2024.101626" target="_blank">https://dx.doi.org/10.1016/j.cpsurg.2024.101626</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_764d3263e5a855e2b3dc05e5774186b0 |
| identifier_str_mv | 10.1016/j.cpsurg.2024.101626 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/27130077 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 CasesYousef Yahia (19756989)Ethar Mohamed (19756992)Muniba Afzal (17734044)Azza Ahmed (8525268)Paul Kurian Vincent (19756995)Ma'mon Qasem (19756998)Husam Saffo (19757001)Prem Chandra (9072038)Antony Raphel Joy (19757004)Biomedical and clinical sciencesClinical sciencesMirizzi syndromeGallstone diseaseEndoscopic Retrograde CholangiopancreatographySurgical outcomesLaparoscopic cholecystectomyCholangitisPreoperative diagnosis<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.</p><h3>Methods</h3><p dir="ltr">This retrospective study aimed to review our institutional experience in diagnosing and managing MS over seven years and four months.</p><h3>Results</h3><p dir="ltr">Among 8200 cholecystectomies, 60 cases of MS were identified, with type 1 being the most prevalent (90%). The mean age of the patients was 44 years, with male predominance (75%). Southeast Asians comprised 56.7% of the study population. The most common presenting symptom was right upper quadrant pain, and 58.3% of the patients were diagnosed with acute cholangitis. Liver enzyme and bilirubin levels were significantly higher in the advanced types. Preoperative diagnosis was achieved in 70% of patients, with MRCP and ERCP being the most effective diagnostic tools. Laparoscopic cholecystectomy was the most common surgical approach (76.7%), particularly in type 1 (79.6%), and decreased to 50% in advanced types. Hepaticojejunostomy was more common in the advanced types.</p><h3>Conclusion</h3><p dir="ltr">This study highlights the importance of early diagnosis and appropriate management of MS considering its rarity and potential complications. The laparoscopic approach is reasonable, especially for type 1 MS and noncomplicated cases. Further research is needed to optimize treatment strategies for this challenging condition.</p><h2>Other Information</h2><p dir="ltr">Published in: Current Problems in Surgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.cpsurg.2024.101626" target="_blank">https://dx.doi.org/10.1016/j.cpsurg.2024.101626</a></p>2024-09-10T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.cpsurg.2024.101626https://figshare.com/articles/journal_contribution/Mirizzi_Syndrome_Mastering_the_Challenge_Characterization_and_Management_Outcomes_in_a_Retrospective_Study_of_60_Cases/27130077CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/271300772024-09-10T03:00:00Z |
| spellingShingle | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases Yousef Yahia (19756989) Biomedical and clinical sciences Clinical sciences Mirizzi syndrome Gallstone disease Endoscopic Retrograde Cholangiopancreatography Surgical outcomes Laparoscopic cholecystectomy Cholangitis Preoperative diagnosis |
| status_str | publishedVersion |
| title | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| title_full | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| title_fullStr | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| title_full_unstemmed | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| title_short | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| title_sort | Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases |
| topic | Biomedical and clinical sciences Clinical sciences Mirizzi syndrome Gallstone disease Endoscopic Retrograde Cholangiopancreatography Surgical outcomes Laparoscopic cholecystectomy Cholangitis Preoperative diagnosis |