Machine learning based model for the early detection of Gestational Diabetes Mellitus

<h3>Background</h3><p dir="ltr">Gestational Diabetes Mellitus (GDM) is one of the most common medical complications during pregnancy. In the Gulf region, the prevalence of GDM is higher than in other parts of the world. Thus, there is a need for the early detection of GDM...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Hesham Zaky (22392529) (author)
مؤلفون آخرون: Eleni Fthenou (216980) (author), Luma Srour (22254409) (author), Thomas Farrell (3933833) (author), Mohammed Bashir (5593550) (author), Nady El Hajj (686554) (author), Tanvir Alam (638619) (author)
منشور في: 2025
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author Hesham Zaky (22392529)
author2 Eleni Fthenou (216980)
Luma Srour (22254409)
Thomas Farrell (3933833)
Mohammed Bashir (5593550)
Nady El Hajj (686554)
Tanvir Alam (638619)
author2_role author
author
author
author
author
author
author_facet Hesham Zaky (22392529)
Eleni Fthenou (216980)
Luma Srour (22254409)
Thomas Farrell (3933833)
Mohammed Bashir (5593550)
Nady El Hajj (686554)
Tanvir Alam (638619)
author_role author
dc.creator.none.fl_str_mv Hesham Zaky (22392529)
Eleni Fthenou (216980)
Luma Srour (22254409)
Thomas Farrell (3933833)
Mohammed Bashir (5593550)
Nady El Hajj (686554)
Tanvir Alam (638619)
dc.date.none.fl_str_mv 2025-03-13T09:00:00Z
dc.identifier.none.fl_str_mv 10.1186/s12911-025-02947-3
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Machine_learning_based_model_for_the_early_detection_of_Gestational_Diabetes_Mellitus/30306520
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Reproductive medicine
Engineering
Biomedical engineering
Health sciences
Health services and systems
Public health
Information and computing sciences
Machine learning
Gestational Diabetes
Machine Learning
Qatar Biobank (QBB)
dc.title.none.fl_str_mv Machine learning based model for the early detection of Gestational Diabetes Mellitus
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Gestational Diabetes Mellitus (GDM) is one of the most common medical complications during pregnancy. In the Gulf region, the prevalence of GDM is higher than in other parts of the world. Thus, there is a need for the early detection of GDM to avoid critical health conditions in newborns and post-pregnancy complexities of mothers.</p><h3>Methods</h3><p dir="ltr">In this article, we propose a machine learning (ML)-based techniques for early detection of GDM. For this purpose, we considered clinical measurements taken during the first trimester to predict the onset of GDM in the second trimester.</p><h3>Results</h3><p dir="ltr">The proposed ensemble-based model achieved high accuracy in predicting the onset of GDM with around 89% accuracy using only the first trimester data. We confirmed biomarkers, i.e., a history of high glucose level/diabetes, insulin and cholesterol, which align with the previous studies. Moreover, we proposed potential novel biomarkers such as HbA1C %, Glucose, MCH, NT pro-BNP, HOMA-IR- (22.5 Scale), HOMA-IR- (405 Scale), Magnesium, Uric Acid. C-Peptide, Triglyceride, Urea, Chloride, Fibrinogen, MCHC, ALT, family history of Diabetes, Vit B12, TSH, Potassium, Alk Phos, FT4, Homocysteine Plasma LC-MSMS, Monocyte Auto.</p><h3>Conclusion</h3><p dir="ltr">We believe our findings will complement the current clinical practice of GDM diagnosis at an early stage of pregnancy, leading toward minimizing its burden on the healthcare system.Source code is available in GitHub at: https://github.com/H-Zaky/GD.git</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Medical Informatics and Decision Making<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12911-025-02947-3" target="_blank">https://dx.doi.org/10.1186/s12911-025-02947-3</a></p>
eu_rights_str_mv openAccess
id Manara2_7669e18fc91b55a33db4f23db81db999
identifier_str_mv 10.1186/s12911-025-02947-3
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/30306520
publishDate 2025
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spelling Machine learning based model for the early detection of Gestational Diabetes MellitusHesham Zaky (22392529)Eleni Fthenou (216980)Luma Srour (22254409)Thomas Farrell (3933833)Mohammed Bashir (5593550)Nady El Hajj (686554)Tanvir Alam (638619)Biomedical and clinical sciencesReproductive medicineEngineeringBiomedical engineeringHealth sciencesHealth services and systemsPublic healthInformation and computing sciencesMachine learningGestational DiabetesMachine LearningQatar Biobank (QBB)<h3>Background</h3><p dir="ltr">Gestational Diabetes Mellitus (GDM) is one of the most common medical complications during pregnancy. In the Gulf region, the prevalence of GDM is higher than in other parts of the world. Thus, there is a need for the early detection of GDM to avoid critical health conditions in newborns and post-pregnancy complexities of mothers.</p><h3>Methods</h3><p dir="ltr">In this article, we propose a machine learning (ML)-based techniques for early detection of GDM. For this purpose, we considered clinical measurements taken during the first trimester to predict the onset of GDM in the second trimester.</p><h3>Results</h3><p dir="ltr">The proposed ensemble-based model achieved high accuracy in predicting the onset of GDM with around 89% accuracy using only the first trimester data. We confirmed biomarkers, i.e., a history of high glucose level/diabetes, insulin and cholesterol, which align with the previous studies. Moreover, we proposed potential novel biomarkers such as HbA1C %, Glucose, MCH, NT pro-BNP, HOMA-IR- (22.5 Scale), HOMA-IR- (405 Scale), Magnesium, Uric Acid. C-Peptide, Triglyceride, Urea, Chloride, Fibrinogen, MCHC, ALT, family history of Diabetes, Vit B12, TSH, Potassium, Alk Phos, FT4, Homocysteine Plasma LC-MSMS, Monocyte Auto.</p><h3>Conclusion</h3><p dir="ltr">We believe our findings will complement the current clinical practice of GDM diagnosis at an early stage of pregnancy, leading toward minimizing its burden on the healthcare system.Source code is available in GitHub at: https://github.com/H-Zaky/GD.git</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Medical Informatics and Decision Making<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12911-025-02947-3" target="_blank">https://dx.doi.org/10.1186/s12911-025-02947-3</a></p>2025-03-13T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1186/s12911-025-02947-3https://figshare.com/articles/journal_contribution/Machine_learning_based_model_for_the_early_detection_of_Gestational_Diabetes_Mellitus/30306520CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303065202025-03-13T09:00:00Z
spellingShingle Machine learning based model for the early detection of Gestational Diabetes Mellitus
Hesham Zaky (22392529)
Biomedical and clinical sciences
Reproductive medicine
Engineering
Biomedical engineering
Health sciences
Health services and systems
Public health
Information and computing sciences
Machine learning
Gestational Diabetes
Machine Learning
Qatar Biobank (QBB)
status_str publishedVersion
title Machine learning based model for the early detection of Gestational Diabetes Mellitus
title_full Machine learning based model for the early detection of Gestational Diabetes Mellitus
title_fullStr Machine learning based model for the early detection of Gestational Diabetes Mellitus
title_full_unstemmed Machine learning based model for the early detection of Gestational Diabetes Mellitus
title_short Machine learning based model for the early detection of Gestational Diabetes Mellitus
title_sort Machine learning based model for the early detection of Gestational Diabetes Mellitus
topic Biomedical and clinical sciences
Reproductive medicine
Engineering
Biomedical engineering
Health sciences
Health services and systems
Public health
Information and computing sciences
Machine learning
Gestational Diabetes
Machine Learning
Qatar Biobank (QBB)