Impact of body composition analysis on male sexual function: A metabolic age study

<h3>Introduction</h3><p dir="ltr">Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism are increasingly prev...

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Main Author: Ahmad Majzoub (14058045) (author)
Other Authors: Haitham Elbardisi (14058048) (author), Sarah Madani (18021670) (author), Kristian Leisegang (8836808) (author), Mohamed Mahdi (665270) (author), Ashok Agarwal (325619) (author), Ralf Henkel (8192964) (author), Kareim Khalafalla (14148807) (author), Sami ElSaid (18021673) (author), Mohamed Arafa (14058042) (author)
Published: 2023
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_version_ 1864513526493609984
author Ahmad Majzoub (14058045)
author2 Haitham Elbardisi (14058048)
Sarah Madani (18021670)
Kristian Leisegang (8836808)
Mohamed Mahdi (665270)
Ashok Agarwal (325619)
Ralf Henkel (8192964)
Kareim Khalafalla (14148807)
Sami ElSaid (18021673)
Mohamed Arafa (14058042)
author2_role author
author
author
author
author
author
author
author
author
author_facet Ahmad Majzoub (14058045)
Haitham Elbardisi (14058048)
Sarah Madani (18021670)
Kristian Leisegang (8836808)
Mohamed Mahdi (665270)
Ashok Agarwal (325619)
Ralf Henkel (8192964)
Kareim Khalafalla (14148807)
Sami ElSaid (18021673)
Mohamed Arafa (14058042)
author_role author
dc.creator.none.fl_str_mv Ahmad Majzoub (14058045)
Haitham Elbardisi (14058048)
Sarah Madani (18021670)
Kristian Leisegang (8836808)
Mohamed Mahdi (665270)
Ashok Agarwal (325619)
Ralf Henkel (8192964)
Kareim Khalafalla (14148807)
Sami ElSaid (18021673)
Mohamed Arafa (14058042)
dc.date.none.fl_str_mv 2023-01-04T03:00:00Z
dc.identifier.none.fl_str_mv 10.3389/fendo.2022.1050441
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Impact_of_body_composition_analysis_on_male_sexual_function_A_metabolic_age_study/25284973
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
body mass index
basal metabolic rate
erectile dysfunction
hypogonadism
metabolic age
dc.title.none.fl_str_mv Impact of body composition analysis on male sexual function: A metabolic age study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Introduction</h3><p dir="ltr">Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism are increasingly prevalent with age, they are also detected among younger men. This study aims to assess the impact of MetAge and body composition on male sexual and gonadal status overall, and particularly in men younger than 40 years of age.</p><h3>Methods</h3><p dir="ltr">This was a cross-sectional study of 90 male healthcare workers, between the ages of 18-55, randomly selected based on their corporation numbers. In addition to Bioelectric Impedance Analysis, subjects were requested to fill the International Index of Erectile Function questionnaire (IIEF-5) and to provide an early morning serum testosterone (T) sample.</p><h3>Results</h3><p dir="ltr">The mean participants’ age was 39.4 ± 9.4 years, MetAge was 45.54 ± 10.35 years, serum T level was 13.68 ± 4.49 nmol/L and BMI was 28.8 ± 4.7 kg/m2. Significant negative correlations were obtained between serum T, MetAge, body weight and fat composition. Significant negative correlations between the IIEF-5 score, MetAge, and fat composition, were only reported in subjects <40 years of age. Significantly lower T levels (p=0.002), significantly older MetAge (p=0.034), and higher BMI (p=0.044) and degree of obesity (p=0.042) were observed in participants <40 years with erectile dysfunction (ED) compared to their counterparts without ED.</p><h3>Discussion</h3><p dir="ltr">MetAge and body composition parameters significantly impact the androgenic state. ED in men <40 years is associated with lower T levels, older MetAge and higher BMI and degree of obesity.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2022.1050441" target="_blank">https://dx.doi.org/10.3389/fendo.2022.1050441</a></p>
eu_rights_str_mv openAccess
id Manara2_7694fb46807fbe12ed7bd3f886addaa1
identifier_str_mv 10.3389/fendo.2022.1050441
network_acronym_str Manara2
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publishDate 2023
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rights_invalid_str_mv CC BY 4.0
spelling Impact of body composition analysis on male sexual function: A metabolic age studyAhmad Majzoub (14058045)Haitham Elbardisi (14058048)Sarah Madani (18021670)Kristian Leisegang (8836808)Mohamed Mahdi (665270)Ashok Agarwal (325619)Ralf Henkel (8192964)Kareim Khalafalla (14148807)Sami ElSaid (18021673)Mohamed Arafa (14058042)Biomedical and clinical sciencesClinical sciencesbody mass indexbasal metabolic rateerectile dysfunctionhypogonadismmetabolic age<h3>Introduction</h3><p dir="ltr">Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism are increasingly prevalent with age, they are also detected among younger men. This study aims to assess the impact of MetAge and body composition on male sexual and gonadal status overall, and particularly in men younger than 40 years of age.</p><h3>Methods</h3><p dir="ltr">This was a cross-sectional study of 90 male healthcare workers, between the ages of 18-55, randomly selected based on their corporation numbers. In addition to Bioelectric Impedance Analysis, subjects were requested to fill the International Index of Erectile Function questionnaire (IIEF-5) and to provide an early morning serum testosterone (T) sample.</p><h3>Results</h3><p dir="ltr">The mean participants’ age was 39.4 ± 9.4 years, MetAge was 45.54 ± 10.35 years, serum T level was 13.68 ± 4.49 nmol/L and BMI was 28.8 ± 4.7 kg/m2. Significant negative correlations were obtained between serum T, MetAge, body weight and fat composition. Significant negative correlations between the IIEF-5 score, MetAge, and fat composition, were only reported in subjects <40 years of age. Significantly lower T levels (p=0.002), significantly older MetAge (p=0.034), and higher BMI (p=0.044) and degree of obesity (p=0.042) were observed in participants <40 years with erectile dysfunction (ED) compared to their counterparts without ED.</p><h3>Discussion</h3><p dir="ltr">MetAge and body composition parameters significantly impact the androgenic state. ED in men <40 years is associated with lower T levels, older MetAge and higher BMI and degree of obesity.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2022.1050441" target="_blank">https://dx.doi.org/10.3389/fendo.2022.1050441</a></p>2023-01-04T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3389/fendo.2022.1050441https://figshare.com/articles/journal_contribution/Impact_of_body_composition_analysis_on_male_sexual_function_A_metabolic_age_study/25284973CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/252849732023-01-04T03:00:00Z
spellingShingle Impact of body composition analysis on male sexual function: A metabolic age study
Ahmad Majzoub (14058045)
Biomedical and clinical sciences
Clinical sciences
body mass index
basal metabolic rate
erectile dysfunction
hypogonadism
metabolic age
status_str publishedVersion
title Impact of body composition analysis on male sexual function: A metabolic age study
title_full Impact of body composition analysis on male sexual function: A metabolic age study
title_fullStr Impact of body composition analysis on male sexual function: A metabolic age study
title_full_unstemmed Impact of body composition analysis on male sexual function: A metabolic age study
title_short Impact of body composition analysis on male sexual function: A metabolic age study
title_sort Impact of body composition analysis on male sexual function: A metabolic age study
topic Biomedical and clinical sciences
Clinical sciences
body mass index
basal metabolic rate
erectile dysfunction
hypogonadism
metabolic age