DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

<h3>Background</h3><p dir="ltr">Colorectal cancer (CRC) is the third most commonly diagnosed human malignancy worldwide. Upregulation of inhibitory immune checkpoints by tumor-infiltrating immune cells (TIICs) or their ligands by tumor cells leads to tumor evasion from ho...

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Main Author: Varun Sasidharan Nair (5396393) (author)
Other Authors: Salman M. Toor (8854751) (author), Rowaida Z. Taha (8854754) (author), Hibah Shaath (5599658) (author), Eyad Elkord (5396390) (author)
Published: 2018
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