Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis

<p dir="ltr">The glycated hemoglobin (HbA1c) is regarded as an essential biomarker for diabetes management. Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. Accurate prediction of HbA1c can greatly improve the way di...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Md Shafiqul Islam (7010348) (author)
مؤلفون آخرون: Marwa Khalid Qaraqe (16891515) (author), SamirBrahim Belhaouari (16891518) (author), Goran Petrovski (129836) (author)
منشور في: 2021
الموضوعات:
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author Md Shafiqul Islam (7010348)
author2 Marwa Khalid Qaraqe (16891515)
SamirBrahim Belhaouari (16891518)
Goran Petrovski (129836)
author2_role author
author
author
author_facet Md Shafiqul Islam (7010348)
Marwa Khalid Qaraqe (16891515)
SamirBrahim Belhaouari (16891518)
Goran Petrovski (129836)
author_role author
dc.creator.none.fl_str_mv Md Shafiqul Islam (7010348)
Marwa Khalid Qaraqe (16891515)
SamirBrahim Belhaouari (16891518)
Goran Petrovski (129836)
dc.date.none.fl_str_mv 2021-04-19T00:00:00Z
dc.identifier.none.fl_str_mv 10.1109/jsen.2021.3073974
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Long_Term_HbA1c_Prediction_Using_Multi-Stage_CGM_Data_Analysis/24042468
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Electronics, sensors and digital hardware
Health sciences
Health services and systems
Sensors
Diabetes
Estimation
Feature extraction
Glucose
Blood
Predictive models
CGM sensor
Diabetes management
HbA1c prediction
Missing data estimation
dc.title.none.fl_str_mv Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">The glycated hemoglobin (HbA1c) is regarded as an essential biomarker for diabetes management. Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. Accurate prediction of HbA1c can greatly improve the way diabetic patients are treated and can potentially avoid related consequences. This study devises a framework to predict HbA1c levels 2-3 months in advance by using blood glucose data collected through continuous glucose monitoring (CGM) sensors and leveraging advanced feature extraction and machine learning techniques. The CGM data may often contain missing values due to sensor issues or not wearing the sensor for some period. Thus, in the paper, a novel missing data estimation method has been proposed for a single data point, multiple data points, and entire day CGM data imputation. The CGM data have been rigorously investigated, and pertinent features were created along with a multi-stage multi-class (MSMC) classification model to predict futuristic HbA1c levels. To evaluate the developed framework, a total of 150 patients' data were sourced from Sidra Medicine, Doha, Qatar, for analysis. The proposed three-staged and five-staged MSMC models predicted HbA1c levels 2-3 months in advance and obtained overall classification accuracies of 88.65% and 83.41%, respectively.</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Sensors Journal<br>License: <a href="https://creativecommons.org/licenses/by/4.0/legalcode" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/jsen.2021.3073974" target="_blank">https://dx.doi.org/10.1109/jsen.2021.3073974</a></p>
eu_rights_str_mv openAccess
id Manara2_7bbbd192df73cbfe4010808613ccbc30
identifier_str_mv 10.1109/jsen.2021.3073974
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24042468
publishDate 2021
repository.mail.fl_str_mv
repository.name.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Long Term HbA1c Prediction Using Multi-Stage CGM Data AnalysisMd Shafiqul Islam (7010348)Marwa Khalid Qaraqe (16891515)SamirBrahim Belhaouari (16891518)Goran Petrovski (129836)Biomedical and clinical sciencesClinical sciencesEngineeringBiomedical engineeringElectronics, sensors and digital hardwareHealth sciencesHealth services and systemsSensorsDiabetesEstimationFeature extractionGlucoseBloodPredictive modelsCGM sensorDiabetes managementHbA1c predictionMissing data estimation<p dir="ltr">The glycated hemoglobin (HbA1c) is regarded as an essential biomarker for diabetes management. Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. Accurate prediction of HbA1c can greatly improve the way diabetic patients are treated and can potentially avoid related consequences. This study devises a framework to predict HbA1c levels 2-3 months in advance by using blood glucose data collected through continuous glucose monitoring (CGM) sensors and leveraging advanced feature extraction and machine learning techniques. The CGM data may often contain missing values due to sensor issues or not wearing the sensor for some period. Thus, in the paper, a novel missing data estimation method has been proposed for a single data point, multiple data points, and entire day CGM data imputation. The CGM data have been rigorously investigated, and pertinent features were created along with a multi-stage multi-class (MSMC) classification model to predict futuristic HbA1c levels. To evaluate the developed framework, a total of 150 patients' data were sourced from Sidra Medicine, Doha, Qatar, for analysis. The proposed three-staged and five-staged MSMC models predicted HbA1c levels 2-3 months in advance and obtained overall classification accuracies of 88.65% and 83.41%, respectively.</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Sensors Journal<br>License: <a href="https://creativecommons.org/licenses/by/4.0/legalcode" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/jsen.2021.3073974" target="_blank">https://dx.doi.org/10.1109/jsen.2021.3073974</a></p>2021-04-19T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1109/jsen.2021.3073974https://figshare.com/articles/journal_contribution/Long_Term_HbA1c_Prediction_Using_Multi-Stage_CGM_Data_Analysis/24042468CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/240424682021-04-19T00:00:00Z
spellingShingle Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
Md Shafiqul Islam (7010348)
Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Electronics, sensors and digital hardware
Health sciences
Health services and systems
Sensors
Diabetes
Estimation
Feature extraction
Glucose
Blood
Predictive models
CGM sensor
Diabetes management
HbA1c prediction
Missing data estimation
status_str publishedVersion
title Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
title_full Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
title_fullStr Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
title_full_unstemmed Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
title_short Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
title_sort Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
topic Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Electronics, sensors and digital hardware
Health sciences
Health services and systems
Sensors
Diabetes
Estimation
Feature extraction
Glucose
Blood
Predictive models
CGM sensor
Diabetes management
HbA1c prediction
Missing data estimation