QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies
<p dir="ltr">Pharmacogenetic (PGx)‐informed medication prescription is a cutting‐edge genomic application in contemporary medicine, offering the potential to overcome the conventional “trial‐and‐error” approach in drug prescription. The ability to use an individual's genetic pro...
محفوظ في:
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| مؤلفون آخرون: | , , , , , , , , , , , , , , , |
| منشور في: |
2024
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513543046430720 |
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| author | Rania Abdel‐latif (14778559) |
| author2 | Radja Badji (14152548) Shaban Mohammed (14150130) Wadha Al‐Muftah (14778553) Hamdi Mbarek (134997) Dima Darwish (14152545) Duha Assaf (21841469) Daoud Al‐Badriyeh (21841472) Hazem Elewa (3592601) Nahla Afifi (193245) Naseer Ahmad Masoodi (21841475) Amr Salah Omar (17151028) Jassim Al Suwaidi (21841478) Salha Bujassoum (18186793) Moza Al Hail (21841481) Said I. Ismail (11721428) Asma Althani (193235) |
| author2_role | author author author author author author author author author author author author author author author author |
| author_facet | Rania Abdel‐latif (14778559) Radja Badji (14152548) Shaban Mohammed (14150130) Wadha Al‐Muftah (14778553) Hamdi Mbarek (134997) Dima Darwish (14152545) Duha Assaf (21841469) Daoud Al‐Badriyeh (21841472) Hazem Elewa (3592601) Nahla Afifi (193245) Naseer Ahmad Masoodi (21841475) Amr Salah Omar (17151028) Jassim Al Suwaidi (21841478) Salha Bujassoum (18186793) Moza Al Hail (21841481) Said I. Ismail (11721428) Asma Althani (193235) |
| author_role | author |
| dc.creator.none.fl_str_mv | Rania Abdel‐latif (14778559) Radja Badji (14152548) Shaban Mohammed (14150130) Wadha Al‐Muftah (14778553) Hamdi Mbarek (134997) Dima Darwish (14152545) Duha Assaf (21841469) Daoud Al‐Badriyeh (21841472) Hazem Elewa (3592601) Nahla Afifi (193245) Naseer Ahmad Masoodi (21841475) Amr Salah Omar (17151028) Jassim Al Suwaidi (21841478) Salha Bujassoum (18186793) Moza Al Hail (21841481) Said I. Ismail (11721428) Asma Althani (193235) |
| dc.date.none.fl_str_mv | 2024-05-31T06:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1111/cts.13800 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/QPGx_CARES_Qatar_pharmacogenetics_clinical_applications_and_research_enhancement_strategies/29715002 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Genetics Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health Pharmacogenetics (PGx) Precision medicine Personalized drug prescription Qatar Genome Program (QGP) Clinical implementation Pharmacogenetic testing Cardiovascular medications |
| dc.title.none.fl_str_mv | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Pharmacogenetic (PGx)‐informed medication prescription is a cutting‐edge genomic application in contemporary medicine, offering the potential to overcome the conventional “trial‐and‐error” approach in drug prescription. The ability to use an individual's genetic profile to predict drug responses allows for personalized drug and dosage selection, thereby enhancing the safety and efficacy of treatments. However, despite significant scientific and clinical advancements in PGx, its integration into routine healthcare practices remains limited. To address this gap, the Qatar Genome Program (QGP) has embarked on an ambitious initiative known as QPGx‐CARES (Qatar Pharmacogenetics Clinical Applications and Research Enhancement Strategies), which aims to set a roadmap for optimizing PGx research and clinical implementation on a national scale. The goal of QPGx‐CARES initiative is to integrate PGx testing into clinical settings with the aim of improving patient health outcomes. In 2022, QGP initiated several implementation projects in various clinical settings. These projects aimed to evaluate the clinical utility of PGx testing, gather valuable insights into the effective dissemination of PGx data to healthcare professionals and patients, and identify the gaps and the challenges for wider adoption. QPGx‐CARES strategy aimed to integrate evidence‐based PGx findings into clinical practice, focusing on implementing PGx testing for cardiovascular medications, supported by robust scientific evidence. The current initiative sets a precedent for the nationwide implementation of precision medicine across diverse clinical domains.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical and Translational Science<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1111/cts.13800" target="_blank">https://dx.doi.org/10.1111/cts.13800</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_7c7ce3e40941ea0771e3a371f693a0f2 |
| identifier_str_mv | 10.1111/cts.13800 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29715002 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategiesRania Abdel‐latif (14778559)Radja Badji (14152548)Shaban Mohammed (14150130)Wadha Al‐Muftah (14778553)Hamdi Mbarek (134997)Dima Darwish (14152545)Duha Assaf (21841469)Daoud Al‐Badriyeh (21841472)Hazem Elewa (3592601)Nahla Afifi (193245)Naseer Ahmad Masoodi (21841475)Amr Salah Omar (17151028)Jassim Al Suwaidi (21841478)Salha Bujassoum (18186793)Moza Al Hail (21841481)Said I. Ismail (11721428)Asma Althani (193235)Biological sciencesGeneticsBiomedical and clinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesPublic healthPharmacogenetics (PGx)Precision medicinePersonalized drug prescriptionQatar Genome Program (QGP)Clinical implementationPharmacogenetic testingCardiovascular medications<p dir="ltr">Pharmacogenetic (PGx)‐informed medication prescription is a cutting‐edge genomic application in contemporary medicine, offering the potential to overcome the conventional “trial‐and‐error” approach in drug prescription. The ability to use an individual's genetic profile to predict drug responses allows for personalized drug and dosage selection, thereby enhancing the safety and efficacy of treatments. However, despite significant scientific and clinical advancements in PGx, its integration into routine healthcare practices remains limited. To address this gap, the Qatar Genome Program (QGP) has embarked on an ambitious initiative known as QPGx‐CARES (Qatar Pharmacogenetics Clinical Applications and Research Enhancement Strategies), which aims to set a roadmap for optimizing PGx research and clinical implementation on a national scale. The goal of QPGx‐CARES initiative is to integrate PGx testing into clinical settings with the aim of improving patient health outcomes. In 2022, QGP initiated several implementation projects in various clinical settings. These projects aimed to evaluate the clinical utility of PGx testing, gather valuable insights into the effective dissemination of PGx data to healthcare professionals and patients, and identify the gaps and the challenges for wider adoption. QPGx‐CARES strategy aimed to integrate evidence‐based PGx findings into clinical practice, focusing on implementing PGx testing for cardiovascular medications, supported by robust scientific evidence. The current initiative sets a precedent for the nationwide implementation of precision medicine across diverse clinical domains.</p><h2>Other Information</h2><p dir="ltr">Published in: Clinical and Translational Science<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1111/cts.13800" target="_blank">https://dx.doi.org/10.1111/cts.13800</a></p>2024-05-31T06:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1111/cts.13800https://figshare.com/articles/journal_contribution/QPGx_CARES_Qatar_pharmacogenetics_clinical_applications_and_research_enhancement_strategies/29715002CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/297150022024-05-31T06:00:00Z |
| spellingShingle | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies Rania Abdel‐latif (14778559) Biological sciences Genetics Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health Pharmacogenetics (PGx) Precision medicine Personalized drug prescription Qatar Genome Program (QGP) Clinical implementation Pharmacogenetic testing Cardiovascular medications |
| status_str | publishedVersion |
| title | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| title_full | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| title_fullStr | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| title_full_unstemmed | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| title_short | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| title_sort | QPGx‐CARES: Qatar pharmacogenetics clinical applications and research enhancement strategies |
| topic | Biological sciences Genetics Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Public health Pharmacogenetics (PGx) Precision medicine Personalized drug prescription Qatar Genome Program (QGP) Clinical implementation Pharmacogenetic testing Cardiovascular medications |