Blockade of PD-1, PD-L1, and TIM-3 Altered Distinct Immune- and Cancer-Related Signaling Pathways in the Transcriptome of Human Breast Cancer Explants
<p dir="ltr">Immune checkpoint inhibitors (ICIs) are yet to have a major advantage over conventional therapies, as only a fraction of patients benefit from the currently approved ICIs and their response rates remain low. We investigated the effects of different ICIs—anti-programmed c...
محفوظ في:
| المؤلف الرئيسي: | Reem Saleh (3513056) (author) |
|---|---|
| مؤلفون آخرون: | Salman M. Toor (8854751) (author), Dana Al-Ali (8854757) (author), Varun Sasidharan Nair (5396393) (author), Eyad Elkord (5396390) (author) |
| منشور في: |
2020
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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مواد مشابهة
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Breast Cancer Cells and PD-1/PD-L1 Blockade Upregulate the Expression of PD-1, CTLA-4, TIM-3 and LAG-3 Immune Checkpoints in CD4+ T Cells
حسب: Reem Saleh (3513056)
منشور في: (2019) -
Breast Cancer Cells and PD-1/PD-L1 Blockade Upregulate the Expression of PD-1, CTLA-4, TIM-3 and LAG-3 Immune Checkpoints in CD4+ T Cells
حسب: Reem Saleh (3513056)
منشور في: (2019) -
Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients
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منشور في: (2023) -
DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
حسب: Varun Sasidharan Nair (5396393)
منشور في: (2018) -
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer
حسب: Varun Sasidharan Nair (5396393)
منشور في: (2018)