Nanoscale studies link amyloid maturity with polyglutamine diseases onset

<p dir="ltr">The presence of expanded poly-glutamine (polyQ) repeats in proteins is directly linked to the pathogenesis of several neurodegenerative diseases, including Huntington’s disease. However, the molecular and structural basis underlying the increased toxicity of aggregates f...

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Main Author: F. S. Ruggeri (19738036) (author)
Other Authors: S. Vieweg (19738039) (author), U. Cendrowska (19738042) (author), G. Longo (19095992) (author), A. Chiki (19738045) (author), H. A. Lashuel (19738048) (author), G. Dietler (19738051) (author)
Published: 2016
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