Patterns of prescription of antipsychotics in Qatar

<div><h2>Objective</h2> <p>Even though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in...

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Main Author: Sami Ouanes (9617363) (author)
Other Authors: Imen Becetti (9617366) (author), Suhaila Ghuloum (796180) (author), Samer Hammoudeh (3095097) (author), Mena Shehata (9617369) (author), Hany Ghabrash (9617372) (author), Areej Yehya (9617375) (author), Hawra Al-Lawati (9617378) (author), Nora Al-Fakhri (9617381) (author), Huma Iram (9617384) (author), Nighat Ajmal (9617387) (author), Yassin Eltorki (9617390) (author), Hassen Al-Amin (3095082) (author)
Published: 2020
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author Sami Ouanes (9617363)
author2 Imen Becetti (9617366)
Suhaila Ghuloum (796180)
Samer Hammoudeh (3095097)
Mena Shehata (9617369)
Hany Ghabrash (9617372)
Areej Yehya (9617375)
Hawra Al-Lawati (9617378)
Nora Al-Fakhri (9617381)
Huma Iram (9617384)
Nighat Ajmal (9617387)
Yassin Eltorki (9617390)
Hassen Al-Amin (3095082)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author_facet Sami Ouanes (9617363)
Imen Becetti (9617366)
Suhaila Ghuloum (796180)
Samer Hammoudeh (3095097)
Mena Shehata (9617369)
Hany Ghabrash (9617372)
Areej Yehya (9617375)
Hawra Al-Lawati (9617378)
Nora Al-Fakhri (9617381)
Huma Iram (9617384)
Nighat Ajmal (9617387)
Yassin Eltorki (9617390)
Hassen Al-Amin (3095082)
author_role author
dc.creator.none.fl_str_mv Sami Ouanes (9617363)
Imen Becetti (9617366)
Suhaila Ghuloum (796180)
Samer Hammoudeh (3095097)
Mena Shehata (9617369)
Hany Ghabrash (9617372)
Areej Yehya (9617375)
Hawra Al-Lawati (9617378)
Nora Al-Fakhri (9617381)
Huma Iram (9617384)
Nighat Ajmal (9617387)
Yassin Eltorki (9617390)
Hassen Al-Amin (3095082)
dc.date.none.fl_str_mv 2020-11-01T00:00:00Z
dc.identifier.none.fl_str_mv 10.1371/journal.pone.0241986
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Patterns_of_prescription_of_antipsychotics_in_Qatar/26021056
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Antipsychotics
Qatar
Mental health and psychiatry
Schizophrenia
Inpatients
Hallucinations
Diagnostic medicine
Outpatients
dc.title.none.fl_str_mv Patterns of prescription of antipsychotics in Qatar
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <div><h2>Objective</h2> <p>Even though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in comparison with the international guidelines, and to scrutinize the sociodemographic and clinical features associated with antipsychotic polypharmacy.</p> <h2>Methods</h2> <p>All the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry–Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.</p> <h2>Results</h2> <p>Our sample consisted of 537 individuals on antipsychotics (2/3 were male; mean age 33.8±10.2 years), prescribed for a psychotic disorder in 57%, a mood disorder in 9.3%, and various other diagnoses in 33.7%. About 55.9% received one antipsychotic, 29.6% received two antipsychotics, and 14.5% received more than two antipsychotics. Polypharmacy was associated with younger age (p = 0.025), being single (p<0.001), the diagnosis of a psychotic disorder (p<0.001), and previous admissions to psychiatry (p<0.001).</p> <h2>Conclusions</h2> <p>Antipsychotic polypharmacy appears to be quite common in Qatar, as it is the case in many other countries, in contrast with most international recommendations. Studies are needed to explore the reasons behind this disparity.</p> </div><h2>Other Information</h2> <p> Published in: PLOS ONE<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0241986" target="_blank">https://dx.doi.org/10.1371/journal.pone.0241986</a></p>
eu_rights_str_mv openAccess
id Manara2_808bdf082aca294ac89b6735dbd72652
identifier_str_mv 10.1371/journal.pone.0241986
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/26021056
publishDate 2020
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Patterns of prescription of antipsychotics in QatarSami Ouanes (9617363)Imen Becetti (9617366)Suhaila Ghuloum (796180)Samer Hammoudeh (3095097)Mena Shehata (9617369)Hany Ghabrash (9617372)Areej Yehya (9617375)Hawra Al-Lawati (9617378)Nora Al-Fakhri (9617381)Huma Iram (9617384)Nighat Ajmal (9617387)Yassin Eltorki (9617390)Hassen Al-Amin (3095082)Biomedical and clinical sciencesClinical sciencesAntipsychoticsQatarMental health and psychiatrySchizophreniaInpatientsHallucinationsDiagnostic medicineOutpatients<div><h2>Objective</h2> <p>Even though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in comparison with the international guidelines, and to scrutinize the sociodemographic and clinical features associated with antipsychotic polypharmacy.</p> <h2>Methods</h2> <p>All the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry–Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.</p> <h2>Results</h2> <p>Our sample consisted of 537 individuals on antipsychotics (2/3 were male; mean age 33.8±10.2 years), prescribed for a psychotic disorder in 57%, a mood disorder in 9.3%, and various other diagnoses in 33.7%. About 55.9% received one antipsychotic, 29.6% received two antipsychotics, and 14.5% received more than two antipsychotics. Polypharmacy was associated with younger age (p = 0.025), being single (p<0.001), the diagnosis of a psychotic disorder (p<0.001), and previous admissions to psychiatry (p<0.001).</p> <h2>Conclusions</h2> <p>Antipsychotic polypharmacy appears to be quite common in Qatar, as it is the case in many other countries, in contrast with most international recommendations. Studies are needed to explore the reasons behind this disparity.</p> </div><h2>Other Information</h2> <p> Published in: PLOS ONE<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0241986" target="_blank">https://dx.doi.org/10.1371/journal.pone.0241986</a></p>2020-11-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1371/journal.pone.0241986https://figshare.com/articles/journal_contribution/Patterns_of_prescription_of_antipsychotics_in_Qatar/26021056CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/260210562020-11-01T00:00:00Z
spellingShingle Patterns of prescription of antipsychotics in Qatar
Sami Ouanes (9617363)
Biomedical and clinical sciences
Clinical sciences
Antipsychotics
Qatar
Mental health and psychiatry
Schizophrenia
Inpatients
Hallucinations
Diagnostic medicine
Outpatients
status_str publishedVersion
title Patterns of prescription of antipsychotics in Qatar
title_full Patterns of prescription of antipsychotics in Qatar
title_fullStr Patterns of prescription of antipsychotics in Qatar
title_full_unstemmed Patterns of prescription of antipsychotics in Qatar
title_short Patterns of prescription of antipsychotics in Qatar
title_sort Patterns of prescription of antipsychotics in Qatar
topic Biomedical and clinical sciences
Clinical sciences
Antipsychotics
Qatar
Mental health and psychiatry
Schizophrenia
Inpatients
Hallucinations
Diagnostic medicine
Outpatients