Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample
<p>We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased f...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , , , |
| Published: |
2020
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1864513555803406336 |
|---|---|
| author | Menatalla Mekhaimar (14103708) |
| author2 | Soha Dargham (3496685) Mohamed El-Shazly (1502728) Jassim Al Suwaidi (284932) Hani Jneid (5038451) Charbel Abi Khalil (781797) |
| author2_role | author author author author author |
| author_facet | Menatalla Mekhaimar (14103708) Soha Dargham (3496685) Mohamed El-Shazly (1502728) Jassim Al Suwaidi (284932) Hani Jneid (5038451) Charbel Abi Khalil (781797) |
| author_role | author |
| dc.creator.none.fl_str_mv | Menatalla Mekhaimar (14103708) Soha Dargham (3496685) Mohamed El-Shazly (1502728) Jassim Al Suwaidi (284932) Hani Jneid (5038451) Charbel Abi Khalil (781797) |
| dc.date.none.fl_str_mv | 2020-09-15T06:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s10741-020-10012-6 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Diabetes-related_cardiovascular_and_economic_burden_in_patients_hospitalized_for_heart_failure_in_the_US_a_recent_temporal_trend_analysis_from_the_National_Inpatient_Sample/21597252 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Economics Applied economics Health sciences Public health Heart failure Diabetes mellitus Mortality Length of stay Cardiovascular disease |
| dc.title.none.fl_str_mv | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased from 40.4 to 46.5% in patients hospitalized for HF. In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). Surprisingly, the presence of DM was associated with lower in-hospital mortality risk, even after adjustment for confounders (adjusted OR = 0.844 (95% CI [0.828–0.860]). Crude mortality gradually decreased from 2.7% in 2005 to 2.4% in 2014 but was still lower than that of non-diabetes patients’ mortality on a yearly comparison basis. Hospitalization for HF also decreased from 211 to 188/100,000 hospitalizations. However, median (IQR) LoS slightly increased from 4 (2–6) to 4 (3–7) days, so did total charges/stay that jumped from 15,704 to 26,858 USD (adjusted for inflation, p trend < 0.001 for both). In total, the prevalence of DM is gradually increasing in HF. However, the temporal trend shows that hospitalization and in-hospital mortality are on a descending slope at a cost of an increasing yearly expenditure and length of stay, even to a larger extent than in patient without DM.</p><h2>Other Information</h2> <p> Published in: Heart Failure Reviews<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10741-020-10012-6" target="_blank">http://dx.doi.org/10.1007/s10741-020-10012-6</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_81160b461b2f388abf87fd1ddd0f9550 |
| identifier_str_mv | 10.1007/s10741-020-10012-6 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21597252 |
| publishDate | 2020 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient SampleMenatalla Mekhaimar (14103708)Soha Dargham (3496685)Mohamed El-Shazly (1502728)Jassim Al Suwaidi (284932)Hani Jneid (5038451)Charbel Abi Khalil (781797)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesEconomicsApplied economicsHealth sciencesPublic healthHeart failureDiabetes mellitusMortalityLength of stayCardiovascular disease<p>We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased from 40.4 to 46.5% in patients hospitalized for HF. In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). Surprisingly, the presence of DM was associated with lower in-hospital mortality risk, even after adjustment for confounders (adjusted OR = 0.844 (95% CI [0.828–0.860]). Crude mortality gradually decreased from 2.7% in 2005 to 2.4% in 2014 but was still lower than that of non-diabetes patients’ mortality on a yearly comparison basis. Hospitalization for HF also decreased from 211 to 188/100,000 hospitalizations. However, median (IQR) LoS slightly increased from 4 (2–6) to 4 (3–7) days, so did total charges/stay that jumped from 15,704 to 26,858 USD (adjusted for inflation, p trend < 0.001 for both). In total, the prevalence of DM is gradually increasing in HF. However, the temporal trend shows that hospitalization and in-hospital mortality are on a descending slope at a cost of an increasing yearly expenditure and length of stay, even to a larger extent than in patient without DM.</p><h2>Other Information</h2> <p> Published in: Heart Failure Reviews<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10741-020-10012-6" target="_blank">http://dx.doi.org/10.1007/s10741-020-10012-6</a></p>2020-09-15T06:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10741-020-10012-6https://figshare.com/articles/journal_contribution/Diabetes-related_cardiovascular_and_economic_burden_in_patients_hospitalized_for_heart_failure_in_the_US_a_recent_temporal_trend_analysis_from_the_National_Inpatient_Sample/21597252CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215972522020-09-15T06:00:00Z |
| spellingShingle | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample Menatalla Mekhaimar (14103708) Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Economics Applied economics Health sciences Public health Heart failure Diabetes mellitus Mortality Length of stay Cardiovascular disease |
| status_str | publishedVersion |
| title | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| title_full | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| title_fullStr | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| title_full_unstemmed | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| title_short | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| title_sort | Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample |
| topic | Biomedical and clinical sciences Cardiovascular medicine and haematology Clinical sciences Economics Applied economics Health sciences Public health Heart failure Diabetes mellitus Mortality Length of stay Cardiovascular disease |