Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study
<h3>Objectives</h3><p dir="ltr">Assess the treatment outcomes and pain relief afforded by full pulpotomy in vital primary molars with clinical symptoms indicative of irreversible pulpitis. </p><h3>Methodology</h3><p dir="ltr">This study w...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , , , , , |
| منشور في: |
2025
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| الموضوعات: | |
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| _version_ | 1864513537138753536 |
|---|---|
| author | Nebu Philip (14779318) |
| author2 | Mawlood Kowash (11654582) Thikrayat Bani-Hani (22438180) Osama El Shahawy (22438183) Ahmad Issa (22318699) Hanan Mohamed (22438186) Mustafa Abdalla (22438189) Suhad Jundi (22438192) Sondos Albadri (3417827) Mandeep Duggal (22393291) Hani Nazzal (14779303) |
| author2_role | author author author author author author author author author author |
| author_facet | Nebu Philip (14779318) Mawlood Kowash (11654582) Thikrayat Bani-Hani (22438180) Osama El Shahawy (22438183) Ahmad Issa (22318699) Hanan Mohamed (22438186) Mustafa Abdalla (22438189) Suhad Jundi (22438192) Sondos Albadri (3417827) Mandeep Duggal (22393291) Hani Nazzal (14779303) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nebu Philip (14779318) Mawlood Kowash (11654582) Thikrayat Bani-Hani (22438180) Osama El Shahawy (22438183) Ahmad Issa (22318699) Hanan Mohamed (22438186) Mustafa Abdalla (22438189) Suhad Jundi (22438192) Sondos Albadri (3417827) Mandeep Duggal (22393291) Hani Nazzal (14779303) |
| dc.date.none.fl_str_mv | 2025-10-03T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.jdent.2025.106140 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Pulpotomy_for_treating_primary_molars_with_clinical_symptoms_indicative_of_irreversible_pulpitis_A_prospective_single-arm_pilot_study/30365752 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Dentistry Paediatrics Vital primary molars Irreversible pulpitis Pulpotomy MTA |
| dc.title.none.fl_str_mv | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Objectives</h3><p dir="ltr">Assess the treatment outcomes and pain relief afforded by full pulpotomy in vital primary molars with clinical symptoms indicative of irreversible pulpitis. </p><h3>Methodology</h3><p dir="ltr">This study was designed as a multi-centre, single-arm, prospective clinical trial registered under ClinicalTrials.gov (NCT06149845). Fifty carious primary molars with clinical symptoms indicative of irreversible pulpitis and pulp intra-operatively assessed to be vital, underwent full coronal pulpotomy following a standardized procedural protocol. Haemostasis was achieved by moderately compressing a 2 % NaOCl-moistened sterile cotton pellet over the radicular pulp stumps for up to 6-minutes. A 2–3 mm layer of mineral trioxide aggregate (MTA) was placed as the pulpotomy medicament and the tooth restored with a pre-formed metal crown. Pre- and post-operative pain scores were evaluated using a validated five-point visual analogue scale (VAS). Clinical and radiographic outcomes were assessed after 6-months. Treatment outcome effects of potential prognostic factors like age, gender, tooth type, site of caries, haemostasis time, and furcal radiolucency were also analysed. </p><h3>Results</h3><p dir="ltr">Intra-group analysis of VAS pain scores revealed significant pain reduction 24-h and 7-d after the pulpotomy treatment procedure. The 6-month post-treatment clinical and radiographic success rates of the pulpotomised primary molars were 100 % and 93.9 %, respectively. No significant association was evident between treatment outcomes and the investigated variables. </p><h3>Conclusions</h3><p dir="ltr">The pain relief afforded and the 6-month clinical and radiographic outcomes indicate that MTA pulpotomy is a successful treatment option for vital primary molars clinically diagnosed with irreversible pulpitis. </p><h3>Clinical Significance</h3><p dir="ltr">This study strengthens the currently available evidence for pulpotomy to be considered as an alternate treatment modality for cariously exposed vital primary molars presenting with symptomatic irreversible pulpitis.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Dentistry<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jdent.2025.106140" target="_blank">https://dx.doi.org/10.1016/j.jdent.2025.106140</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_811b9eab74e735b5967668d19ee369ac |
| identifier_str_mv | 10.1016/j.jdent.2025.106140 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30365752 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot studyNebu Philip (14779318)Mawlood Kowash (11654582)Thikrayat Bani-Hani (22438180)Osama El Shahawy (22438183)Ahmad Issa (22318699)Hanan Mohamed (22438186)Mustafa Abdalla (22438189)Suhad Jundi (22438192)Sondos Albadri (3417827)Mandeep Duggal (22393291)Hani Nazzal (14779303)Biomedical and clinical sciencesDentistryPaediatricsVital primary molarsIrreversible pulpitisPulpotomyMTA<h3>Objectives</h3><p dir="ltr">Assess the treatment outcomes and pain relief afforded by full pulpotomy in vital primary molars with clinical symptoms indicative of irreversible pulpitis. </p><h3>Methodology</h3><p dir="ltr">This study was designed as a multi-centre, single-arm, prospective clinical trial registered under ClinicalTrials.gov (NCT06149845). Fifty carious primary molars with clinical symptoms indicative of irreversible pulpitis and pulp intra-operatively assessed to be vital, underwent full coronal pulpotomy following a standardized procedural protocol. Haemostasis was achieved by moderately compressing a 2 % NaOCl-moistened sterile cotton pellet over the radicular pulp stumps for up to 6-minutes. A 2–3 mm layer of mineral trioxide aggregate (MTA) was placed as the pulpotomy medicament and the tooth restored with a pre-formed metal crown. Pre- and post-operative pain scores were evaluated using a validated five-point visual analogue scale (VAS). Clinical and radiographic outcomes were assessed after 6-months. Treatment outcome effects of potential prognostic factors like age, gender, tooth type, site of caries, haemostasis time, and furcal radiolucency were also analysed. </p><h3>Results</h3><p dir="ltr">Intra-group analysis of VAS pain scores revealed significant pain reduction 24-h and 7-d after the pulpotomy treatment procedure. The 6-month post-treatment clinical and radiographic success rates of the pulpotomised primary molars were 100 % and 93.9 %, respectively. No significant association was evident between treatment outcomes and the investigated variables. </p><h3>Conclusions</h3><p dir="ltr">The pain relief afforded and the 6-month clinical and radiographic outcomes indicate that MTA pulpotomy is a successful treatment option for vital primary molars clinically diagnosed with irreversible pulpitis. </p><h3>Clinical Significance</h3><p dir="ltr">This study strengthens the currently available evidence for pulpotomy to be considered as an alternate treatment modality for cariously exposed vital primary molars presenting with symptomatic irreversible pulpitis.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Dentistry<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jdent.2025.106140" target="_blank">https://dx.doi.org/10.1016/j.jdent.2025.106140</a></p>2025-10-03T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.jdent.2025.106140https://figshare.com/articles/journal_contribution/Pulpotomy_for_treating_primary_molars_with_clinical_symptoms_indicative_of_irreversible_pulpitis_A_prospective_single-arm_pilot_study/30365752CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303657522025-10-03T09:00:00Z |
| spellingShingle | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study Nebu Philip (14779318) Biomedical and clinical sciences Dentistry Paediatrics Vital primary molars Irreversible pulpitis Pulpotomy MTA |
| status_str | publishedVersion |
| title | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| title_full | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| title_fullStr | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| title_full_unstemmed | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| title_short | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| title_sort | Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study |
| topic | Biomedical and clinical sciences Dentistry Paediatrics Vital primary molars Irreversible pulpitis Pulpotomy MTA |