Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
<h3>Background</h3><p dir="ltr">Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. <u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related...
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2024
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| _version_ | 1864513539570401280 |
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| author | Mohammed Al-Hamdani (16962702) |
| author2 | Farah Issa (22282345) Marah Abdulla (22282348) Saja A. Abdallah (22282351) Amal Al-Haidose (19438003) Atiyeh M. Abdallah (10742523) |
| author2_role | author author author author author |
| author_facet | Mohammed Al-Hamdani (16962702) Farah Issa (22282345) Marah Abdulla (22282348) Saja A. Abdallah (22282351) Amal Al-Haidose (19438003) Atiyeh M. Abdallah (10742523) |
| author_role | author |
| dc.creator.none.fl_str_mv | Mohammed Al-Hamdani (16962702) Farah Issa (22282345) Marah Abdulla (22282348) Saja A. Abdallah (22282351) Amal Al-Haidose (19438003) Atiyeh M. Abdallah (10742523) |
| dc.date.none.fl_str_mv | 2024-12-22T18:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.jocd.2024.101547 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Associations_between_Bone_Mineral_Density_and_WOMAC_Scores_in_Healthy_Individuals_Insights_from_the_Qatar_Biobank/30173002 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Sports science and exercise Bone mineral density WOMAC scores Healthy Individuals Pain and stiffness Physical function |
| dc.title.none.fl_str_mv | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. <u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. Here we assessed whether BMD measured at specific sites predicts WOMAC scores in healthy individuals whilst controlling for sociodemographic variables. </p><h3>Methodology</h3><p dir="ltr">BMD, sociodemographic, and WOMAC data were collected from 1764 <u>healthy adult</u> individuals attending the Qatar <u>Biobank</u> (QBB). <u>Multiple linear regression</u> was used to examine associations between sociodemographic factors, total body BMD and BMD related to specific skeletal sites (including femoral (femoral neck and trochanter), trunk, pelvis and total spine), and the three WOMAC subscales (pain, stiffness, and physical function). </p><h3>Results</h3><p dir="ltr">After controlling for sociodemographic variables, total body and specific BMD measures did not predict pain. However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R<sup>2</sup> = 0.065, ΔF(7, 1724) = 3.34, p= 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. Total body BMD measures also significantly contributed to predicting compromised physical function (R<sup>2</sup> = 0.091, ΔF(7, 1724) = 3.762, p < 0.001) after controlling for sociodemographic variables, with a higher total body BMD associated with an increase in compromised physical function. </p><h3>Conclusion</h3><p dir="ltr">Total body BMD seems to be a more important predictor of stiffness and physical function than specific skeletal sites BMD measures. Monitoring BMD may have important implications for <u>osteoarthritis</u> patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Clinical Densitometry<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jocd.2024.101547" target="_blank">https://dx.doi.org/10.1016/j.jocd.2024.101547</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_8276b8da597419b5ccf4a933ee4ec1a0 |
| identifier_str_mv | 10.1016/j.jocd.2024.101547 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30173002 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar BiobankMohammed Al-Hamdani (16962702)Farah Issa (22282345)Marah Abdulla (22282348)Saja A. Abdallah (22282351)Amal Al-Haidose (19438003)Atiyeh M. Abdallah (10742523)Biomedical and clinical sciencesClinical sciencesHealth sciencesEpidemiologySports science and exerciseBone mineral densityWOMAC scoresHealthy IndividualsPain and stiffnessPhysical function<h3>Background</h3><p dir="ltr">Bone mineral density (BMD) is an indicator of bone health that predicts future bone fractures. <u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. Here we assessed whether BMD measured at specific sites predicts WOMAC scores in healthy individuals whilst controlling for sociodemographic variables. </p><h3>Methodology</h3><p dir="ltr">BMD, sociodemographic, and WOMAC data were collected from 1764 <u>healthy adult</u> individuals attending the Qatar <u>Biobank</u> (QBB). <u>Multiple linear regression</u> was used to examine associations between sociodemographic factors, total body BMD and BMD related to specific skeletal sites (including femoral (femoral neck and trochanter), trunk, pelvis and total spine), and the three WOMAC subscales (pain, stiffness, and physical function). </p><h3>Results</h3><p dir="ltr">After controlling for sociodemographic variables, total body and specific BMD measures did not predict pain. However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R<sup>2</sup> = 0.065, ΔF(7, 1724) = 3.34, p= 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. Total body BMD measures also significantly contributed to predicting compromised physical function (R<sup>2</sup> = 0.091, ΔF(7, 1724) = 3.762, p < 0.001) after controlling for sociodemographic variables, with a higher total body BMD associated with an increase in compromised physical function. </p><h3>Conclusion</h3><p dir="ltr">Total body BMD seems to be a more important predictor of stiffness and physical function than specific skeletal sites BMD measures. Monitoring BMD may have important implications for <u>osteoarthritis</u> patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Clinical Densitometry<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jocd.2024.101547" target="_blank">https://dx.doi.org/10.1016/j.jocd.2024.101547</a></p>2024-12-22T18:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.jocd.2024.101547https://figshare.com/articles/journal_contribution/Associations_between_Bone_Mineral_Density_and_WOMAC_Scores_in_Healthy_Individuals_Insights_from_the_Qatar_Biobank/30173002CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301730022024-12-22T18:00:00Z |
| spellingShingle | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank Mohammed Al-Hamdani (16962702) Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Sports science and exercise Bone mineral density WOMAC scores Healthy Individuals Pain and stiffness Physical function |
| status_str | publishedVersion |
| title | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| title_full | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| title_fullStr | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| title_full_unstemmed | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| title_short | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| title_sort | Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank |
| topic | Biomedical and clinical sciences Clinical sciences Health sciences Epidemiology Sports science and exercise Bone mineral density WOMAC scores Healthy Individuals Pain and stiffness Physical function |