Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review

<p dir="ltr">Tumor necrosis factor-alpha (TNF-α) inhibitors are widely used to treat various inflammatory conditions, where they have demonstrated excellent efficacy and tolerability. However, increased risk of infections is one of the most important concerns associated with these ag...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mousa Hussein (14137052) (author)
مؤلفون آخرون: Irfan Ul Haq (9853260) (author), Mansoor Hameed (11324145) (author), Abbas Alabbas (14777569) (author), Hamad Abdel Hadi (11819159) (author), Anam Elarabi (17075254) (author), Issam Al-Bozom (4711098) (author)
منشور في: 2021
الموضوعات:
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author Mousa Hussein (14137052)
author2 Irfan Ul Haq (9853260)
Mansoor Hameed (11324145)
Abbas Alabbas (14777569)
Hamad Abdel Hadi (11819159)
Anam Elarabi (17075254)
Issam Al-Bozom (4711098)
author2_role author
author
author
author
author
author
author_facet Mousa Hussein (14137052)
Irfan Ul Haq (9853260)
Mansoor Hameed (11324145)
Abbas Alabbas (14777569)
Hamad Abdel Hadi (11819159)
Anam Elarabi (17075254)
Issam Al-Bozom (4711098)
author_role author
dc.creator.none.fl_str_mv Mousa Hussein (14137052)
Irfan Ul Haq (9853260)
Mansoor Hameed (11324145)
Abbas Alabbas (14777569)
Hamad Abdel Hadi (11819159)
Anam Elarabi (17075254)
Issam Al-Bozom (4711098)
dc.date.none.fl_str_mv 2021-06-24T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.rmcr.2021.101459
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Isolated_pulmonary_cryptococcosis_in_a_patient_with_Crohn_s_disease_treated_with_infliximab_A_case_report_and_literature_review/24433207
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Tumor necrosis factor-alpha (TNF-α) inhibitors
Infliximab
Crohn's disease
Cryptococcosis
Fungal infections
dc.title.none.fl_str_mv Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Tumor necrosis factor-alpha (TNF-α) inhibitors are widely used to treat various inflammatory conditions, where they have demonstrated excellent efficacy and tolerability. However, increased risk of infections is one of the most important concerns associated with these agents. Reactivation of tuberculosis and fungal infections have emerged as significant infective complications of anti-TNF-α therapy. Cryptococcus infection is an opportunistic fungal infection that can occur in patients receiving anti-TNF-α treatment. We report a rare case of isolated pulmonary cryptococcosis in a patient undergoing anti-TNF-α therapy for Crohn's disease. Our case should alert clinicians to the increased incidence and atypical presentation of pulmonary cryptococcosis in patients receiving anti-TNF-α treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: Respiratory Medicine Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.rmcr.2021.101459" target="_blank">https://dx.doi.org/10.1016/j.rmcr.2021.101459</a></p>
eu_rights_str_mv openAccess
id Manara2_838050fd6e9a8acc863f6b14766fea0f
identifier_str_mv 10.1016/j.rmcr.2021.101459
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24433207
publishDate 2021
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rights_invalid_str_mv CC BY 4.0
spelling Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature reviewMousa Hussein (14137052)Irfan Ul Haq (9853260)Mansoor Hameed (11324145)Abbas Alabbas (14777569)Hamad Abdel Hadi (11819159)Anam Elarabi (17075254)Issam Al-Bozom (4711098)Biomedical and clinical sciencesCardiovascular medicine and haematologyTumor necrosis factor-alpha (TNF-α) inhibitorsInfliximabCrohn's diseaseCryptococcosisFungal infections<p dir="ltr">Tumor necrosis factor-alpha (TNF-α) inhibitors are widely used to treat various inflammatory conditions, where they have demonstrated excellent efficacy and tolerability. However, increased risk of infections is one of the most important concerns associated with these agents. Reactivation of tuberculosis and fungal infections have emerged as significant infective complications of anti-TNF-α therapy. Cryptococcus infection is an opportunistic fungal infection that can occur in patients receiving anti-TNF-α treatment. We report a rare case of isolated pulmonary cryptococcosis in a patient undergoing anti-TNF-α therapy for Crohn's disease. Our case should alert clinicians to the increased incidence and atypical presentation of pulmonary cryptococcosis in patients receiving anti-TNF-α treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: Respiratory Medicine Case Reports<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.rmcr.2021.101459" target="_blank">https://dx.doi.org/10.1016/j.rmcr.2021.101459</a></p>2021-06-24T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.rmcr.2021.101459https://figshare.com/articles/journal_contribution/Isolated_pulmonary_cryptococcosis_in_a_patient_with_Crohn_s_disease_treated_with_infliximab_A_case_report_and_literature_review/24433207CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/244332072021-06-24T00:00:00Z
spellingShingle Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
Mousa Hussein (14137052)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Tumor necrosis factor-alpha (TNF-α) inhibitors
Infliximab
Crohn's disease
Cryptococcosis
Fungal infections
status_str publishedVersion
title Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
title_full Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
title_fullStr Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
title_full_unstemmed Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
title_short Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
title_sort Isolated pulmonary cryptococcosis in a patient with Crohn's disease treated with infliximab: A case report and literature review
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Tumor necrosis factor-alpha (TNF-α) inhibitors
Infliximab
Crohn's disease
Cryptococcosis
Fungal infections