Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus

<p dir="ltr">Dental calculus, a main contributor of periodontal diseases, is mostly composed of inorganic calcium phosphate species such as dicalcium phosphate, whitlockite, octa calcium phosphate, and hydroxyapatite. Under physiological pH 7.4, dicalcium phosphates can gradually int...

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Main Author: Amir Elhadad (18192829) (author)
Other Authors: Tayebeh Basiri (430303) (author), Ashwaq Al-Hashedi (22457626) (author), Sophia Smith (11791221) (author), Hanan Moussa (9131626) (author), Sadiya Veettil (22457629) (author), Eva Mª Pérez Soriano (22457632) (author), Faleh Tamimi (2867255) (author)
Published: 2025
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author Amir Elhadad (18192829)
author2 Tayebeh Basiri (430303)
Ashwaq Al-Hashedi (22457626)
Sophia Smith (11791221)
Hanan Moussa (9131626)
Sadiya Veettil (22457629)
Eva Mª Pérez Soriano (22457632)
Faleh Tamimi (2867255)
author2_role author
author
author
author
author
author
author
author_facet Amir Elhadad (18192829)
Tayebeh Basiri (430303)
Ashwaq Al-Hashedi (22457626)
Sophia Smith (11791221)
Hanan Moussa (9131626)
Sadiya Veettil (22457629)
Eva Mª Pérez Soriano (22457632)
Faleh Tamimi (2867255)
author_role author
dc.creator.none.fl_str_mv Amir Elhadad (18192829)
Tayebeh Basiri (430303)
Ashwaq Al-Hashedi (22457626)
Sophia Smith (11791221)
Hanan Moussa (9131626)
Sadiya Veettil (22457629)
Eva Mª Pérez Soriano (22457632)
Faleh Tamimi (2867255)
dc.date.none.fl_str_mv 2025-03-15T09:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s10856-025-06867-6
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Reactivity_of_aragonite_with_dicalcium_phosphate_facilitates_removal_of_dental_calculus/30393145
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Dentistry
Dental calculus
Periodontal disease
Aragonite
Hydroxyapatite
Calcium phosphate
dc.title.none.fl_str_mv Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Dental calculus, a main contributor of periodontal diseases, is mostly composed of inorganic calcium phosphate species such as dicalcium phosphate, whitlockite, octa calcium phosphate, and hydroxyapatite. Under physiological pH 7.4, dicalcium phosphates can gradually interact with calcium carbonate to form hydroxyapatite. Therefore, we hypothesized that aragonite (Arg) could react with dental calculus, facilitating its removal. To assess the reactivity of Arg with dental calculus, we examined the changes in surface morphology, composition, and topography of Arg and dental calculus upon exposure to each other in an aqueous environment. The impact of Arg on the removal of dental calculus was assessed by brushing polished sections of dental calculus, enamel, and dentin with slurries of Arg and measuring the depth of abrasion using a stylus profilometer. Our results demonstrate that Arg can react with dental calculus in aqueous environment. This reaction increases calculus surface roughness which in turn facilitate dental calculus removal by brushing. Aragonite could be a promising abrasive for toothpaste design for management of dental calculus.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Materials Science: Materials in Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10856-025-06867-6" target="_blank">https://dx.doi.org/10.1007/s10856-025-06867-6</a></p>
eu_rights_str_mv openAccess
id Manara2_8567255683e81be6ae9e4b2c8efd2306
identifier_str_mv 10.1007/s10856-025-06867-6
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/30393145
publishDate 2025
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rights_invalid_str_mv CC BY 4.0
spelling Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculusAmir Elhadad (18192829)Tayebeh Basiri (430303)Ashwaq Al-Hashedi (22457626)Sophia Smith (11791221)Hanan Moussa (9131626)Sadiya Veettil (22457629)Eva Mª Pérez Soriano (22457632)Faleh Tamimi (2867255)Biomedical and clinical sciencesClinical sciencesDentistryDental calculusPeriodontal diseaseAragoniteHydroxyapatiteCalcium phosphate<p dir="ltr">Dental calculus, a main contributor of periodontal diseases, is mostly composed of inorganic calcium phosphate species such as dicalcium phosphate, whitlockite, octa calcium phosphate, and hydroxyapatite. Under physiological pH 7.4, dicalcium phosphates can gradually interact with calcium carbonate to form hydroxyapatite. Therefore, we hypothesized that aragonite (Arg) could react with dental calculus, facilitating its removal. To assess the reactivity of Arg with dental calculus, we examined the changes in surface morphology, composition, and topography of Arg and dental calculus upon exposure to each other in an aqueous environment. The impact of Arg on the removal of dental calculus was assessed by brushing polished sections of dental calculus, enamel, and dentin with slurries of Arg and measuring the depth of abrasion using a stylus profilometer. Our results demonstrate that Arg can react with dental calculus in aqueous environment. This reaction increases calculus surface roughness which in turn facilitate dental calculus removal by brushing. Aragonite could be a promising abrasive for toothpaste design for management of dental calculus.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Materials Science: Materials in Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10856-025-06867-6" target="_blank">https://dx.doi.org/10.1007/s10856-025-06867-6</a></p>2025-03-15T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10856-025-06867-6https://figshare.com/articles/journal_contribution/Reactivity_of_aragonite_with_dicalcium_phosphate_facilitates_removal_of_dental_calculus/30393145CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303931452025-03-15T09:00:00Z
spellingShingle Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
Amir Elhadad (18192829)
Biomedical and clinical sciences
Clinical sciences
Dentistry
Dental calculus
Periodontal disease
Aragonite
Hydroxyapatite
Calcium phosphate
status_str publishedVersion
title Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
title_full Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
title_fullStr Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
title_full_unstemmed Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
title_short Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
title_sort Reactivity of aragonite with dicalcium phosphate facilitates removal of dental calculus
topic Biomedical and clinical sciences
Clinical sciences
Dentistry
Dental calculus
Periodontal disease
Aragonite
Hydroxyapatite
Calcium phosphate