Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study

<h3>Background</h3><p dir="ltr">Research gaps refer to unanswered questions in the existing body of knowledge, either due to a lack of studies or inconclusive results. Research gaps are essential starting points and motivation in scientific research. Traditional methods f...

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Main Author: Alaa Abd-alrazaq (17058018) (author)
Other Authors: Abdulqadir J Nashwan (17991280) (author), Zubair Shah (231886) (author), Ahmad Abujaber (9100064) (author), Dari Alhuwail (6497858) (author), Jens Schneider (16885948) (author), Rawan AlSaad (14159019) (author), Hazrat Ali (421019) (author), Waleed Alomoush (19325926) (author), Arfan Ahmed (17541309) (author), Sarah Aziz (17541312) (author)
Published: 2024
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_version_ 1864513509679693824
author Alaa Abd-alrazaq (17058018)
author2 Abdulqadir J Nashwan (17991280)
Zubair Shah (231886)
Ahmad Abujaber (9100064)
Dari Alhuwail (6497858)
Jens Schneider (16885948)
Rawan AlSaad (14159019)
Hazrat Ali (421019)
Waleed Alomoush (19325926)
Arfan Ahmed (17541309)
Sarah Aziz (17541312)
author2_role author
author
author
author
author
author
author
author
author
author
author_facet Alaa Abd-alrazaq (17058018)
Abdulqadir J Nashwan (17991280)
Zubair Shah (231886)
Ahmad Abujaber (9100064)
Dari Alhuwail (6497858)
Jens Schneider (16885948)
Rawan AlSaad (14159019)
Hazrat Ali (421019)
Waleed Alomoush (19325926)
Arfan Ahmed (17541309)
Sarah Aziz (17541312)
author_role author
dc.creator.none.fl_str_mv Alaa Abd-alrazaq (17058018)
Abdulqadir J Nashwan (17991280)
Zubair Shah (231886)
Ahmad Abujaber (9100064)
Dari Alhuwail (6497858)
Jens Schneider (16885948)
Rawan AlSaad (14159019)
Hazrat Ali (421019)
Waleed Alomoush (19325926)
Arfan Ahmed (17541309)
Sarah Aziz (17541312)
dc.date.none.fl_str_mv 2024-03-05T03:00:00Z
dc.identifier.none.fl_str_mv 10.2196/49411
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Machine_Learning_Based_Approach_for_Identifying_Research_Gaps_COVID-19_as_a_Case_Study/26491117
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Health sciences
Epidemiology
Public health
Information and computing sciences
Machine learning
research gap
research topic
research topics
scientific literature
literature review
machine learning
COVID-19
BERTopic
topic clustering
text analysis
BERT
NLP
natural language processing
review methods
review methodology
SARS-CoV-2
coronavirus
dc.title.none.fl_str_mv Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Research gaps refer to unanswered questions in the existing body of knowledge, either due to a lack of studies or inconclusive results. Research gaps are essential starting points and motivation in scientific research. Traditional methods for identifying research gaps, such as literature reviews and expert opinions, can be time consuming, labor intensive, and prone to bias. They may also fall short when dealing with rapidly evolving or time-sensitive subjects. Thus, innovative scalable approaches are needed to identify research gaps, systematically assess the literature, and prioritize areas for further study in the topic of interest.</p><h3>Objective</h3><p dir="ltr">In this paper, we propose a machine learning–based approach for identifying research gaps through the analysis of scientific literature. We used the COVID-19 pandemic as a case study.</p><h3>Methods</h3><p dir="ltr">We conducted an analysis to identify research gaps in COVID-19 literature using the COVID-19 Open Research (CORD-19) data set, which comprises 1,121,433 papers related to the COVID-19 pandemic. Our approach is based on the BERTopic topic modeling technique, which leverages transformers and class-based term frequency-inverse document frequency to create dense clusters allowing for easily interpretable topics. Our BERTopic-based approach involves 3 stages: embedding documents, clustering documents (dimension reduction and clustering), and representing topics (generating candidates and maximizing candidate relevance).</p><h3>Results</h3><p dir="ltr">After applying the study selection criteria, we included 33,206 abstracts in the analysis of this study. The final list of research gaps identified 21 different areas, which were grouped into 6 principal topics. These topics were: “virus of COVID-19,” “risk factors of COVID-19,” “prevention of COVID-19,” “treatment of COVID-19,” “health care delivery during COVID-19,” “and impact of COVID-19.” The most prominent topic, observed in over half of the analyzed studies, was “the impact of COVID-19.”</p><h3>Conclusions</h3><p dir="ltr">The proposed machine learning–based approach has the potential to identify research gaps in scientific literature. This study is not intended to replace individual literature research within a selected topic. Instead, it can serve as a guide to formulate precise literature search queries in specific areas associated with research questions that previous publications have earmarked for future exploration. Future research should leverage an up-to-date list of studies that are retrieved from the most common databases in the target area. When feasible, full texts or, at minimum, discussion sections should be analyzed rather than limiting their analysis to abstracts. Furthermore, future studies could evaluate more efficient modeling algorithms, especially those combining topic modeling with statistical uncertainty quantification, such as conformal prediction.</p><h2>Other Information</h2><p dir="ltr">Published in: JMIR Formative Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/49411" target="_blank">https://dx.doi.org/10.2196/49411</a></p>
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oai_identifier_str oai:figshare.com:article/26491117
publishDate 2024
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rights_invalid_str_mv CC BY 4.0
spelling Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case StudyAlaa Abd-alrazaq (17058018)Abdulqadir J Nashwan (17991280)Zubair Shah (231886)Ahmad Abujaber (9100064)Dari Alhuwail (6497858)Jens Schneider (16885948)Rawan AlSaad (14159019)Hazrat Ali (421019)Waleed Alomoush (19325926)Arfan Ahmed (17541309)Sarah Aziz (17541312)Health sciencesEpidemiologyPublic healthInformation and computing sciencesMachine learningresearch gapresearch topicresearch topicsscientific literatureliterature reviewmachine learningCOVID-19BERTopictopic clusteringtext analysisBERTNLPnatural language processingreview methodsreview methodologySARS-CoV-2coronavirus<h3>Background</h3><p dir="ltr">Research gaps refer to unanswered questions in the existing body of knowledge, either due to a lack of studies or inconclusive results. Research gaps are essential starting points and motivation in scientific research. Traditional methods for identifying research gaps, such as literature reviews and expert opinions, can be time consuming, labor intensive, and prone to bias. They may also fall short when dealing with rapidly evolving or time-sensitive subjects. Thus, innovative scalable approaches are needed to identify research gaps, systematically assess the literature, and prioritize areas for further study in the topic of interest.</p><h3>Objective</h3><p dir="ltr">In this paper, we propose a machine learning–based approach for identifying research gaps through the analysis of scientific literature. We used the COVID-19 pandemic as a case study.</p><h3>Methods</h3><p dir="ltr">We conducted an analysis to identify research gaps in COVID-19 literature using the COVID-19 Open Research (CORD-19) data set, which comprises 1,121,433 papers related to the COVID-19 pandemic. Our approach is based on the BERTopic topic modeling technique, which leverages transformers and class-based term frequency-inverse document frequency to create dense clusters allowing for easily interpretable topics. Our BERTopic-based approach involves 3 stages: embedding documents, clustering documents (dimension reduction and clustering), and representing topics (generating candidates and maximizing candidate relevance).</p><h3>Results</h3><p dir="ltr">After applying the study selection criteria, we included 33,206 abstracts in the analysis of this study. The final list of research gaps identified 21 different areas, which were grouped into 6 principal topics. These topics were: “virus of COVID-19,” “risk factors of COVID-19,” “prevention of COVID-19,” “treatment of COVID-19,” “health care delivery during COVID-19,” “and impact of COVID-19.” The most prominent topic, observed in over half of the analyzed studies, was “the impact of COVID-19.”</p><h3>Conclusions</h3><p dir="ltr">The proposed machine learning–based approach has the potential to identify research gaps in scientific literature. This study is not intended to replace individual literature research within a selected topic. Instead, it can serve as a guide to formulate precise literature search queries in specific areas associated with research questions that previous publications have earmarked for future exploration. Future research should leverage an up-to-date list of studies that are retrieved from the most common databases in the target area. When feasible, full texts or, at minimum, discussion sections should be analyzed rather than limiting their analysis to abstracts. Furthermore, future studies could evaluate more efficient modeling algorithms, especially those combining topic modeling with statistical uncertainty quantification, such as conformal prediction.</p><h2>Other Information</h2><p dir="ltr">Published in: JMIR Formative Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/49411" target="_blank">https://dx.doi.org/10.2196/49411</a></p>2024-03-05T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2196/49411https://figshare.com/articles/journal_contribution/Machine_Learning_Based_Approach_for_Identifying_Research_Gaps_COVID-19_as_a_Case_Study/26491117CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/264911172024-03-05T03:00:00Z
spellingShingle Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
Alaa Abd-alrazaq (17058018)
Health sciences
Epidemiology
Public health
Information and computing sciences
Machine learning
research gap
research topic
research topics
scientific literature
literature review
machine learning
COVID-19
BERTopic
topic clustering
text analysis
BERT
NLP
natural language processing
review methods
review methodology
SARS-CoV-2
coronavirus
status_str publishedVersion
title Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
title_full Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
title_fullStr Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
title_full_unstemmed Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
title_short Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
title_sort Machine Learning–Based Approach for Identifying Research Gaps: COVID-19 as a Case Study
topic Health sciences
Epidemiology
Public health
Information and computing sciences
Machine learning
research gap
research topic
research topics
scientific literature
literature review
machine learning
COVID-19
BERTopic
topic clustering
text analysis
BERT
NLP
natural language processing
review methods
review methodology
SARS-CoV-2
coronavirus