Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications
<p dir="ltr">Fungal infections have emerged as a significant global health concern, with <i>Candida</i> species, opportunistic yeasts living symbiotically in various parts of the human body, playing a major role in pathogenic invasions. The overuse and inappropriate appli...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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| _version_ | 1864513537625292800 |
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| author | Atefeh Esmaeili (462337) |
| author2 | Iman Saleh (14152878) Mohammed H. Abu-Dieyeh (14152761) |
| author2_role | author author |
| author_facet | Atefeh Esmaeili (462337) Iman Saleh (14152878) Mohammed H. Abu-Dieyeh (14152761) |
| author_role | author |
| dc.creator.none.fl_str_mv | Atefeh Esmaeili (462337) Iman Saleh (14152878) Mohammed H. Abu-Dieyeh (14152761) |
| dc.date.none.fl_str_mv | 2025-03-29T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s11101-025-10093-x |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Antifungal_potential_of_plant-based_extracts_against_i_Candida_i_species_values_safety_concerns_and_possible_applications/30306013 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biological sciences Evolutionary biology Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Traditional, complementary and integrative medicine Fungal infection Candidiasis Antifungal drug resistance In vivo In vitro Toxicity |
| dc.title.none.fl_str_mv | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Fungal infections have emerged as a significant global health concern, with <i>Candida</i> species, opportunistic yeasts living symbiotically in various parts of the human body, playing a major role in pathogenic invasions. The overuse and inappropriate application of conventional antifungal drugs have contributed to frequent treatment failures and the alarming rise of drug-resistant strains, prompting a growing interest in exploring naturally derived alternatives. Plants, known for their therapeutic properties throughout history, are currently being investigated as potential agents for combating fungal diseases, including Candidiasis infections. This review compiled and examined findings from both in vitro and in vivo studies conducted over the past decade, evaluating the antifungal effectiveness of plant-derived extracts against various <i>Candida</i> species. The results were summarized in detailed tables and discussed comprehensively. Additionally, this review addressed the safety considerations and assessment of these herbal remedies and highlighted the necessity for further extensive research in this promising and expanding area.</p><h2>Other Information</h2><p dir="ltr">Published in: Phytochemistry Reviews<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11101-025-10093-x" target="_blank">https://dx.doi.org/10.1007/s11101-025-10093-x</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_8c065a1b155f1c11f73f7e1cb6032728 |
| identifier_str_mv | 10.1007/s11101-025-10093-x |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30306013 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applicationsAtefeh Esmaeili (462337)Iman Saleh (14152878)Mohammed H. Abu-Dieyeh (14152761)Biological sciencesEvolutionary biologyBiomedical and clinical sciencesPharmacology and pharmaceutical sciencesHealth sciencesTraditional, complementary and integrative medicineFungal infectionCandidiasisAntifungal drug resistanceIn vivoIn vitro Toxicity<p dir="ltr">Fungal infections have emerged as a significant global health concern, with <i>Candida</i> species, opportunistic yeasts living symbiotically in various parts of the human body, playing a major role in pathogenic invasions. The overuse and inappropriate application of conventional antifungal drugs have contributed to frequent treatment failures and the alarming rise of drug-resistant strains, prompting a growing interest in exploring naturally derived alternatives. Plants, known for their therapeutic properties throughout history, are currently being investigated as potential agents for combating fungal diseases, including Candidiasis infections. This review compiled and examined findings from both in vitro and in vivo studies conducted over the past decade, evaluating the antifungal effectiveness of plant-derived extracts against various <i>Candida</i> species. The results were summarized in detailed tables and discussed comprehensively. Additionally, this review addressed the safety considerations and assessment of these herbal remedies and highlighted the necessity for further extensive research in this promising and expanding area.</p><h2>Other Information</h2><p dir="ltr">Published in: Phytochemistry Reviews<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11101-025-10093-x" target="_blank">https://dx.doi.org/10.1007/s11101-025-10093-x</a></p>2025-03-29T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11101-025-10093-xhttps://figshare.com/articles/journal_contribution/Antifungal_potential_of_plant-based_extracts_against_i_Candida_i_species_values_safety_concerns_and_possible_applications/30306013CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/303060132025-03-29T09:00:00Z |
| spellingShingle | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications Atefeh Esmaeili (462337) Biological sciences Evolutionary biology Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Traditional, complementary and integrative medicine Fungal infection Candidiasis Antifungal drug resistance In vivo In vitro Toxicity |
| status_str | publishedVersion |
| title | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| title_full | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| title_fullStr | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| title_full_unstemmed | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| title_short | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| title_sort | Antifungal potential of plant-based extracts against <i>Candida</i> species: values, safety concerns, and possible applications |
| topic | Biological sciences Evolutionary biology Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Health sciences Traditional, complementary and integrative medicine Fungal infection Candidiasis Antifungal drug resistance In vivo In vitro Toxicity |