Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

<p dir="ltr">Non-melanoma skin cancer (NMSC), encompassing basal and squamous cell carcinoma, is the most prevalent cancer in the United States. While surgical removal remains the conventional therapy with a 95% 5-year cure rate, there is a growing interest in exploring alternative t...

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Main Author: Kirti S. Prabhu (4246144) (author)
Other Authors: Fareed Ahmad (134672) (author), Shilpa Kuttikrishnan (3520079) (author), Rari Leo (19325845) (author), Tayyiba Akbar Ali (14152572) (author), Mahmoud Izadi (12899508) (author), Jericha M. Mateo (17563293) (author), Majid Alam (14158959) (author), Aamir Ahmad (233201) (author), Ammira S. Al-Shabeeb Akil (18206017) (author), Ajaz A. Bhat (12984701) (author), Joerg Buddenkotte (6293584) (author), Ehsan Pourkarimi (541179) (author), Martin Steinhoff (5340194) (author), Shahab Uddin (154400) (author)
Published: 2024
Subjects:
Biomedical and clinical sciences
Clinical sciences
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
Non-Melanoma Skin Cancer (NMSC)
Basal Cell Carcinoma
Squamous Cell Carcinoma
Mitochondrial Permeability
Cytochrome C
Reactive Oxygen Species (ROS)
Cancer Research
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