Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity

Inhibition of cytochrome P450 epoxygenase promotes endothelium-to-mesenchymal transition and exacerbates doxorubicin-induced cardiovascular toxicity

<h3>Background</h3><p dir="ltr">Doxorubicin (DOX) is a potent chemotherapy widely used in treating various neoplastic diseases. However, the clinical use of DOX is limited due to its potential toxic effect on the cardiovascular system. Thus, identifying the pathway involv...

Full description

Saved in:
Bibliographic Details
Main Author: Hevna Dhulkifle (14724821) (author)
Other Authors: Lubna Therachiyil (4246156) (author), Maram H. Hasan (22047845) (author), Tahseen S. Sayed (14724824) (author), Shahd M. Younis (17380453) (author), Hesham M. Korashy (1474849) (author), Huseyin C. Yalcin (6695099) (author), Zaid H. Maayah (9236533) (author)
Published: 2024
Subjects:
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Pharmacology and pharmaceutical sciences
Doxorubicin
Endothelial
Mesenchymal
Cytochrome p450
Epoxyeicosatrienoic acids
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items