Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes

<p dir="ltr">Accurately predicting the severity of subarachnoid hemorrhage (SAH) is critical for informing clinical decisions and improving patient outcomes. This study addresses the challenges of imbalanced data in SAH severity classification by employing the Modified Rankin Scale (...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Muhammad Mohsin Khan (22150360) (author)
مؤلفون آخرون: Adiba Tabassum Chowdhury (19444792) (author), Md. Shaheenur Islam Sumon (17983810) (author), Shaikh Nissaruddin Maheboob (22565696) (author), Arshad Ali (638656) (author), Abdul Nasser Thabet (22565699) (author), Ghaya Al-Rumaihi (22565702) (author), Sirajeddin Belkhair (17151106) (author), Ghanem AlSulaiti (22565705) (author), Ali Ayyad (149042) (author), Noman Shah (22150363) (author), Anwarul Hasan (1332066) (author), Shona Pedersen (2792278) (author), Muhammad E. H. Chowdhury (14150526) (author)
منشور في: 2025
الموضوعات:
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author Muhammad Mohsin Khan (22150360)
author2 Adiba Tabassum Chowdhury (19444792)
Md. Shaheenur Islam Sumon (17983810)
Shaikh Nissaruddin Maheboob (22565696)
Arshad Ali (638656)
Abdul Nasser Thabet (22565699)
Ghaya Al-Rumaihi (22565702)
Sirajeddin Belkhair (17151106)
Ghanem AlSulaiti (22565705)
Ali Ayyad (149042)
Noman Shah (22150363)
Anwarul Hasan (1332066)
Shona Pedersen (2792278)
Muhammad E. H. Chowdhury (14150526)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Muhammad Mohsin Khan (22150360)
Adiba Tabassum Chowdhury (19444792)
Md. Shaheenur Islam Sumon (17983810)
Shaikh Nissaruddin Maheboob (22565696)
Arshad Ali (638656)
Abdul Nasser Thabet (22565699)
Ghaya Al-Rumaihi (22565702)
Sirajeddin Belkhair (17151106)
Ghanem AlSulaiti (22565705)
Ali Ayyad (149042)
Noman Shah (22150363)
Anwarul Hasan (1332066)
Shona Pedersen (2792278)
Muhammad E. H. Chowdhury (14150526)
author_role author
dc.creator.none.fl_str_mv Muhammad Mohsin Khan (22150360)
Adiba Tabassum Chowdhury (19444792)
Md. Shaheenur Islam Sumon (17983810)
Shaikh Nissaruddin Maheboob (22565696)
Arshad Ali (638656)
Abdul Nasser Thabet (22565699)
Ghaya Al-Rumaihi (22565702)
Sirajeddin Belkhair (17151106)
Ghanem AlSulaiti (22565705)
Ali Ayyad (149042)
Noman Shah (22150363)
Anwarul Hasan (1332066)
Shona Pedersen (2792278)
Muhammad E. H. Chowdhury (14150526)
dc.date.none.fl_str_mv 2025-07-10T09:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s10143-025-03678-9
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Multi-class_subarachnoid_hemorrhage_severity_prediction_addressing_challenges_in_predicting_rare_outcomes/30542501
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Neurosciences
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Machine learning
Subarachnoid hemorrhage
Severity prediction
Modified rankin scale
Imbalanced data
Electronic health record
dc.title.none.fl_str_mv Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Accurately predicting the severity of subarachnoid hemorrhage (SAH) is critical for informing clinical decisions and improving patient outcomes. This study addresses the challenges of imbalanced data in SAH severity classification by employing the Modified Rankin Scale (MRS) within a three-stage classification framework. We utilize a three-stage approach to effectively categorize SAH severity. In the first stage, we performed binary classification, grouping SAH severity into “Good Outcome” (class 0), which includes MRS levels 0, 1, 2, and 3, and “Poor Outcome” (class 1), encompassing levels 4, 5, and 6. Feature selection was done using a Random Forest algorithm to identify the top 20 features for the SAH severity prediction. We evaluated thirteen machine learning models at each stage, selecting the top-performing classifiers to optimize results. The dataset comprised 535 samples across seven MRS severity levels and was validated using 5-fold cross-validation and diverse subgroups to ensure robust model performance across various scenarios. Binary classification in the first stage achieved approximately 90% accuracy with Extra Trees. In the second stage, targeting the “Good Outcome” group, the Random Forest model reached 88% accuracy, while in the third stage, it achieved 86% accuracy for the “Poor Outcome” group. By increasing accuracy across unbalanced classes and emphasizing its potential for practical use, the multi-stage technique presents a promising solution for predicting the severity of SAH. Future research will concentrate on additional tuning to improve the model’s efficacy in actual healthcare environments.</p><h2>Other Information</h2><p dir="ltr">Published in: Neurosurgical Review<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10143-025-03678-9" target="_blank">https://dx.doi.org/10.1007/s10143-025-03678-9</a></p>
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id Manara2_996b5d91dcd7377d788075a3a9fb4143
identifier_str_mv 10.1007/s10143-025-03678-9
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/30542501
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spelling Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomesMuhammad Mohsin Khan (22150360)Adiba Tabassum Chowdhury (19444792)Md. Shaheenur Islam Sumon (17983810)Shaikh Nissaruddin Maheboob (22565696)Arshad Ali (638656)Abdul Nasser Thabet (22565699)Ghaya Al-Rumaihi (22565702)Sirajeddin Belkhair (17151106)Ghanem AlSulaiti (22565705)Ali Ayyad (149042)Noman Shah (22150363)Anwarul Hasan (1332066)Shona Pedersen (2792278)Muhammad E. H. Chowdhury (14150526)Biomedical and clinical sciencesNeurosciencesHealth sciencesHealth services and systemsInformation and computing sciencesArtificial intelligenceMachine learningSubarachnoid hemorrhageSeverity predictionModified rankin scaleImbalanced dataElectronic health record<p dir="ltr">Accurately predicting the severity of subarachnoid hemorrhage (SAH) is critical for informing clinical decisions and improving patient outcomes. This study addresses the challenges of imbalanced data in SAH severity classification by employing the Modified Rankin Scale (MRS) within a three-stage classification framework. We utilize a three-stage approach to effectively categorize SAH severity. In the first stage, we performed binary classification, grouping SAH severity into “Good Outcome” (class 0), which includes MRS levels 0, 1, 2, and 3, and “Poor Outcome” (class 1), encompassing levels 4, 5, and 6. Feature selection was done using a Random Forest algorithm to identify the top 20 features for the SAH severity prediction. We evaluated thirteen machine learning models at each stage, selecting the top-performing classifiers to optimize results. The dataset comprised 535 samples across seven MRS severity levels and was validated using 5-fold cross-validation and diverse subgroups to ensure robust model performance across various scenarios. Binary classification in the first stage achieved approximately 90% accuracy with Extra Trees. In the second stage, targeting the “Good Outcome” group, the Random Forest model reached 88% accuracy, while in the third stage, it achieved 86% accuracy for the “Poor Outcome” group. By increasing accuracy across unbalanced classes and emphasizing its potential for practical use, the multi-stage technique presents a promising solution for predicting the severity of SAH. Future research will concentrate on additional tuning to improve the model’s efficacy in actual healthcare environments.</p><h2>Other Information</h2><p dir="ltr">Published in: Neurosurgical Review<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10143-025-03678-9" target="_blank">https://dx.doi.org/10.1007/s10143-025-03678-9</a></p>2025-07-10T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10143-025-03678-9https://figshare.com/articles/journal_contribution/Multi-class_subarachnoid_hemorrhage_severity_prediction_addressing_challenges_in_predicting_rare_outcomes/30542501CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/305425012025-07-10T09:00:00Z
spellingShingle Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
Muhammad Mohsin Khan (22150360)
Biomedical and clinical sciences
Neurosciences
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Machine learning
Subarachnoid hemorrhage
Severity prediction
Modified rankin scale
Imbalanced data
Electronic health record
status_str publishedVersion
title Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
title_full Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
title_fullStr Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
title_full_unstemmed Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
title_short Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
title_sort Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes
topic Biomedical and clinical sciences
Neurosciences
Health sciences
Health services and systems
Information and computing sciences
Artificial intelligence
Machine learning
Subarachnoid hemorrhage
Severity prediction
Modified rankin scale
Imbalanced data
Electronic health record