Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva

<p dir="ltr">The control of movements is a fundamental feature shared by all animals. At the most basic level, simple movements are generated by coordinated neural activity and muscle contraction patterns that are controlled by the central nervous system. How behavioral responses to...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Swetha B. M. Gowda (16442142) (author)
مؤلفون آخرون: Safa Salim (9186786) (author), Farhan Mohammad (256409) (author)
منشور في: 2021
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author Swetha B. M. Gowda (16442142)
author2 Safa Salim (9186786)
Farhan Mohammad (256409)
author2_role author
author
author_facet Swetha B. M. Gowda (16442142)
Safa Salim (9186786)
Farhan Mohammad (256409)
author_role author
dc.creator.none.fl_str_mv Swetha B. M. Gowda (16442142)
Safa Salim (9186786)
Farhan Mohammad (256409)
dc.date.none.fl_str_mv 2021-01-25T00:00:00Z
dc.identifier.none.fl_str_mv 10.3390/biology10020090
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Anatomy_and_Neural_Pathways_Modulating_Distinct_Locomotor_Behaviors_in_em_Drosophila_em_Larva/23576001
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biological sciences
Genetics
Microbiology
Biomedical and clinical sciences
Neurosciences
Biomedical engineering
brain circuits
neural communication
Drosophila larvae
locomotion
sensory systems
information processing
dc.title.none.fl_str_mv Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">The control of movements is a fundamental feature shared by all animals. At the most basic level, simple movements are generated by coordinated neural activity and muscle contraction patterns that are controlled by the central nervous system. How behavioral responses to various sensory inputs are processed and integrated by the downstream neural network to produce flexible and adaptive behaviors remains an intense area of investigation in many laboratories. Due to recent advances in experimental techniques, many fundamental neural pathways underlying animal movements have now been elucidated. For example, while the role of motor neurons in locomotion has been studied in great detail, the roles of interneurons in animal movements in both basic and noxious environments have only recently been realized. However, the genetic and transmitter identities of many of these interneurons remains unclear. In this review, we provide an overview of the underlying circuitry and neural pathways required by <i>Drosophila</i> larvae to produce successful movements. By improving our understanding of locomotor circuitry in model systems such as <i>Drosophila</i>, we will have a better understanding of how neural circuits in organisms with different bodies and brains lead to distinct locomotion types at the organism level. The understanding of genetic and physiological components of these movements types also provides directions to understand movements in higher organisms.</p><h2>Other Information</h2><p dir="ltr">Published in: Biology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.3390/biology10020090" target="_blank">http://dx.doi.org/10.3390/biology10020090</a></p>
eu_rights_str_mv openAccess
id Manara2_9b42fdab3b60d29b22cee93b581bf74e
identifier_str_mv 10.3390/biology10020090
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/23576001
publishDate 2021
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spelling Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila LarvaSwetha B. M. Gowda (16442142)Safa Salim (9186786)Farhan Mohammad (256409)Biological sciencesGeneticsMicrobiologyBiomedical and clinical sciencesNeurosciencesBiomedical engineeringbrain circuitsneural communicationDrosophila larvaelocomotionsensory systemsinformation processing<p dir="ltr">The control of movements is a fundamental feature shared by all animals. At the most basic level, simple movements are generated by coordinated neural activity and muscle contraction patterns that are controlled by the central nervous system. How behavioral responses to various sensory inputs are processed and integrated by the downstream neural network to produce flexible and adaptive behaviors remains an intense area of investigation in many laboratories. Due to recent advances in experimental techniques, many fundamental neural pathways underlying animal movements have now been elucidated. For example, while the role of motor neurons in locomotion has been studied in great detail, the roles of interneurons in animal movements in both basic and noxious environments have only recently been realized. However, the genetic and transmitter identities of many of these interneurons remains unclear. In this review, we provide an overview of the underlying circuitry and neural pathways required by <i>Drosophila</i> larvae to produce successful movements. By improving our understanding of locomotor circuitry in model systems such as <i>Drosophila</i>, we will have a better understanding of how neural circuits in organisms with different bodies and brains lead to distinct locomotion types at the organism level. The understanding of genetic and physiological components of these movements types also provides directions to understand movements in higher organisms.</p><h2>Other Information</h2><p dir="ltr">Published in: Biology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.3390/biology10020090" target="_blank">http://dx.doi.org/10.3390/biology10020090</a></p>2021-01-25T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.3390/biology10020090https://figshare.com/articles/journal_contribution/Anatomy_and_Neural_Pathways_Modulating_Distinct_Locomotor_Behaviors_in_em_Drosophila_em_Larva/23576001CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/235760012021-01-25T00:00:00Z
spellingShingle Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
Swetha B. M. Gowda (16442142)
Biological sciences
Genetics
Microbiology
Biomedical and clinical sciences
Neurosciences
Biomedical engineering
brain circuits
neural communication
Drosophila larvae
locomotion
sensory systems
information processing
status_str publishedVersion
title Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
title_full Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
title_fullStr Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
title_full_unstemmed Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
title_short Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
title_sort Anatomy and Neural Pathways Modulating Distinct Locomotor Behaviors in Drosophila Larva
topic Biological sciences
Genetics
Microbiology
Biomedical and clinical sciences
Neurosciences
Biomedical engineering
brain circuits
neural communication
Drosophila larvae
locomotion
sensory systems
information processing