Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation

<h3>Background</h3><p dir="ltr">Trisomy 21 (T21) is associated with intellectual disability that ranges from mild to profound with an average intellectual quotient of around 50. Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in lif...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Larissa Haertle (3864310) (author)
مؤلفون آخرون: Tobias Müller (163591) (author), Roy Lardenoije (6689108) (author), Anna Maierhofer (4017935) (author), Marcus Dittrich (167737) (author), Renzo J. M. Riemens (18618934) (author), Samantha Stora (8132457) (author), Mathilde Roche (8132460) (author), Markus Leber (573362) (author), Steffi Riedel-Heller (434691) (author), Michael Wagner (56165) (author), Martin Scherer (434692) (author), Aimé Ravel (144418) (author), Clotilde Mircher (254970) (author), Cecile Cieuta-Walti (8132463) (author), Sophie Durand (5639963) (author), Daniel L. A. van de Hove (18618937) (author), Per Hoffmann (429526) (author), Alfredo Ramirez (361375) (author), Thomas Haaf (342924) (author), Nady El Hajj (686554) (author), André Mégarbané (5649685) (author)
منشور في: 2019
الموضوعات:
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