A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems
<p dir="ltr">Magnetic core–shell nanocarriers have been attracting growing interest owing to their physicochemical and structural properties. The main principles of magnetic nanoparticles (MNPs) are localized treatment and stability under the effect of external magnetic fields. Furth...
محفوظ في:
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| مؤلفون آخرون: | , , |
| منشور في: |
2019
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513525948350464 |
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| author | Kholoud Albinali (18090601) |
| author2 | Moustafa Zagho (18059980) Yonghui Deng (1367988) Ahmed Elzatahry (1515655) |
| author2_role | author author author |
| author_facet | Kholoud Albinali (18090601) Moustafa Zagho (18059980) Yonghui Deng (1367988) Ahmed Elzatahry (1515655) |
| author_role | author |
| dc.creator.none.fl_str_mv | Kholoud Albinali (18090601) Moustafa Zagho (18059980) Yonghui Deng (1367988) Ahmed Elzatahry (1515655) |
| dc.date.none.fl_str_mv | 2019-03-06T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.2147/ijn.s193981 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/A_perspective_on_magnetic_core_shell_carriers_for_responsive_and_targeted_drug_delivery_systems/25331035 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Chemical sciences Organic chemistry magnetic mesoporous core–shell drug carriers active targeting passive targeting controlled release targeted cancer treatment |
| dc.title.none.fl_str_mv | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p dir="ltr">Magnetic core–shell nanocarriers have been attracting growing interest owing to their physicochemical and structural properties. The main principles of magnetic nanoparticles (MNPs) are localized treatment and stability under the effect of external magnetic fields. Furthermore, these MNPs can be coated or functionalized to gain a responsive property to a specific trigger, such as pH, heat, or even enzymes. Current investigations have been focused on the employment of this concept in cancer therapies. The evaluation of magnetic core–shell materials includes their magnetization properties, toxicity, and efficacy in drug uptake and release. This review discusses some categories of magnetic core–shell drug carriers based on Fe<sub>2</sub>O<sub>3</sub> and Fe<sub>3</sub>O<sub>4</sub> as the core, and different shells such as poly(lactic-co-glycolic acid), poly(vinylpyrrolidone), chitosan, silica, calcium silicate, metal, and lipids. In addition, the review addresses their recent potential applications for cancer treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Nanomedicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/ijn.s193981" target="_blank">https://dx.doi.org/10.2147/ijn.s193981</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_9e8b074e0c8ceb92af3b1fd6d69d30ad |
| identifier_str_mv | 10.2147/ijn.s193981 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25331035 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systemsKholoud Albinali (18090601)Moustafa Zagho (18059980)Yonghui Deng (1367988)Ahmed Elzatahry (1515655)Biomedical and clinical sciencesPharmacology and pharmaceutical sciencesChemical sciencesOrganic chemistrymagneticmesoporouscore–shelldrug carriersactive targetingpassive targetingcontrolled releasetargeted cancer treatment<p dir="ltr">Magnetic core–shell nanocarriers have been attracting growing interest owing to their physicochemical and structural properties. The main principles of magnetic nanoparticles (MNPs) are localized treatment and stability under the effect of external magnetic fields. Furthermore, these MNPs can be coated or functionalized to gain a responsive property to a specific trigger, such as pH, heat, or even enzymes. Current investigations have been focused on the employment of this concept in cancer therapies. The evaluation of magnetic core–shell materials includes their magnetization properties, toxicity, and efficacy in drug uptake and release. This review discusses some categories of magnetic core–shell drug carriers based on Fe<sub>2</sub>O<sub>3</sub> and Fe<sub>3</sub>O<sub>4</sub> as the core, and different shells such as poly(lactic-co-glycolic acid), poly(vinylpyrrolidone), chitosan, silica, calcium silicate, metal, and lipids. In addition, the review addresses their recent potential applications for cancer treatment.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Nanomedicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/ijn.s193981" target="_blank">https://dx.doi.org/10.2147/ijn.s193981</a></p>2019-03-06T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2147/ijn.s193981https://figshare.com/articles/journal_contribution/A_perspective_on_magnetic_core_shell_carriers_for_responsive_and_targeted_drug_delivery_systems/25331035CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/253310352019-03-06T03:00:00Z |
| spellingShingle | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems Kholoud Albinali (18090601) Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Chemical sciences Organic chemistry magnetic mesoporous core–shell drug carriers active targeting passive targeting controlled release targeted cancer treatment |
| status_str | publishedVersion |
| title | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| title_full | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| title_fullStr | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| title_full_unstemmed | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| title_short | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| title_sort | A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems |
| topic | Biomedical and clinical sciences Pharmacology and pharmaceutical sciences Chemical sciences Organic chemistry magnetic mesoporous core–shell drug carriers active targeting passive targeting controlled release targeted cancer treatment |