A customised fetal growth and birthweight standard for Qatar: a population-based cohort study
<h3>Objectives</h3><p dir="ltr">Customized birthweight centiles have improved the detection of small for gestational age (SGA) and large for gestational age (LGA) babies compared to existing population standards. This study used perinatal registry data to derive coefficie...
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2024
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| _version_ | 1864513540987027456 |
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| author | Thomas Farrell (3933833) |
| author2 | Fathima Minisha (16475100) Najat Khenyab (14585514) Najah Mohammed Ali (22155016) Sawsan Al Obaidly (17760147) Salwa Abu Yaqoub (22155019) Abdul Rouf Pallivalappil (17760150) Nader Al-Dewik (4166527) Hilal AlRifai (17075071) Oliver Hugh (22155022) Jason Gardosi (3424466) |
| author2_role | author author author author author author author author author author |
| author_facet | Thomas Farrell (3933833) Fathima Minisha (16475100) Najat Khenyab (14585514) Najah Mohammed Ali (22155016) Sawsan Al Obaidly (17760147) Salwa Abu Yaqoub (22155019) Abdul Rouf Pallivalappil (17760150) Nader Al-Dewik (4166527) Hilal AlRifai (17075071) Oliver Hugh (22155022) Jason Gardosi (3424466) |
| author_role | author |
| dc.creator.none.fl_str_mv | Thomas Farrell (3933833) Fathima Minisha (16475100) Najat Khenyab (14585514) Najah Mohammed Ali (22155016) Sawsan Al Obaidly (17760147) Salwa Abu Yaqoub (22155019) Abdul Rouf Pallivalappil (17760150) Nader Al-Dewik (4166527) Hilal AlRifai (17075071) Oliver Hugh (22155022) Jason Gardosi (3424466) |
| dc.date.none.fl_str_mv | 2024-08-20T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1515/jpm-2024-0060 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/A_customised_fetal_growth_and_birthweight_standard_for_Qatar_a_population-based_cohort_study/30023101 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Reproductive medicine Health sciences Public health birthweight customized growth charts GROW stillbirth fetal growth restriction |
| dc.title.none.fl_str_mv | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Objectives</h3><p dir="ltr">Customized birthweight centiles have improved the detection of small for gestational age (SGA) and large for gestational age (LGA) babies compared to existing population standards. This study used perinatal registry data to derive coefficients for developing customized growth charts for Qatar.</p><h3>Methods</h3><p dir="ltr">The PEARL registry data on women delivering in Qatar (2017–2018) was used to develop a multivariable linear regression model predicting optimal birthweight. Physiological variables included gestational age, maternal height, weight, ethnicity, parity, and sex of the baby. Pathological variables such as hypertension, preexisting and gestational diabetes and smoking were calculated and excluded to derive the optimal weight at term.</p><h3>Results</h3><p dir="ltr">The regression model found a term optimal birthweight of 3,235 g for a Qatari nationality mother with median height (159 cm), booking weight (72 kg), parity (1) and gestation at birth (276 days) at the end of an uncomplicated pregnancy. Constitutional coefficients significantly affecting birthweight were gestational age, height, weight, and parity. The main pathological factors were preexisting diabetes (increase by +175.7 g) and smoking (decrease by −190.9 g). The SGA and LGA rates in the entire cohort after applying the population-specific customized centiles were 11.1 and 12.2 %, respectively (contrasting with the Hadlock standard: SGA-26.3 % and LGA-1.8 %, and Fenton standard: SGA-12.9 % and LGA-4.0 %).</p><h3>Conclusions</h3><p dir="ltr">Constitutional and pathological variations in fetal growth and birthweight apply in the maternity population in Qatar and have been quantified to allow the generation of customised charts for better identification of pregnancies with abnormal growth. Currently in-use population standards may misdiagnose many SGA and LGA babies.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Perinatal Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/jpm-2024-0060" target="_blank">https://dx.doi.org/10.1515/jpm-2024-0060</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_9f424ef5048229f693553ea72a12c6b8 |
| identifier_str_mv | 10.1515/jpm-2024-0060 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30023101 |
| publishDate | 2024 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | A customised fetal growth and birthweight standard for Qatar: a population-based cohort studyThomas Farrell (3933833)Fathima Minisha (16475100)Najat Khenyab (14585514)Najah Mohammed Ali (22155016)Sawsan Al Obaidly (17760147)Salwa Abu Yaqoub (22155019)Abdul Rouf Pallivalappil (17760150)Nader Al-Dewik (4166527)Hilal AlRifai (17075071)Oliver Hugh (22155022)Jason Gardosi (3424466)Biomedical and clinical sciencesReproductive medicineHealth sciencesPublic healthbirthweightcustomized growth chartsGROWstillbirthfetal growth restriction<h3>Objectives</h3><p dir="ltr">Customized birthweight centiles have improved the detection of small for gestational age (SGA) and large for gestational age (LGA) babies compared to existing population standards. This study used perinatal registry data to derive coefficients for developing customized growth charts for Qatar.</p><h3>Methods</h3><p dir="ltr">The PEARL registry data on women delivering in Qatar (2017–2018) was used to develop a multivariable linear regression model predicting optimal birthweight. Physiological variables included gestational age, maternal height, weight, ethnicity, parity, and sex of the baby. Pathological variables such as hypertension, preexisting and gestational diabetes and smoking were calculated and excluded to derive the optimal weight at term.</p><h3>Results</h3><p dir="ltr">The regression model found a term optimal birthweight of 3,235 g for a Qatari nationality mother with median height (159 cm), booking weight (72 kg), parity (1) and gestation at birth (276 days) at the end of an uncomplicated pregnancy. Constitutional coefficients significantly affecting birthweight were gestational age, height, weight, and parity. The main pathological factors were preexisting diabetes (increase by +175.7 g) and smoking (decrease by −190.9 g). The SGA and LGA rates in the entire cohort after applying the population-specific customized centiles were 11.1 and 12.2 %, respectively (contrasting with the Hadlock standard: SGA-26.3 % and LGA-1.8 %, and Fenton standard: SGA-12.9 % and LGA-4.0 %).</p><h3>Conclusions</h3><p dir="ltr">Constitutional and pathological variations in fetal growth and birthweight apply in the maternity population in Qatar and have been quantified to allow the generation of customised charts for better identification of pregnancies with abnormal growth. Currently in-use population standards may misdiagnose many SGA and LGA babies.</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Perinatal Medicine<br>License: <a href="http://creativecommons.org/licenses/by/4.0" target="_blank">http://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1515/jpm-2024-0060" target="_blank">https://dx.doi.org/10.1515/jpm-2024-0060</a></p>2024-08-20T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1515/jpm-2024-0060https://figshare.com/articles/journal_contribution/A_customised_fetal_growth_and_birthweight_standard_for_Qatar_a_population-based_cohort_study/30023101CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/300231012024-08-20T09:00:00Z |
| spellingShingle | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study Thomas Farrell (3933833) Biomedical and clinical sciences Reproductive medicine Health sciences Public health birthweight customized growth charts GROW stillbirth fetal growth restriction |
| status_str | publishedVersion |
| title | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| title_full | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| title_fullStr | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| title_full_unstemmed | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| title_short | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| title_sort | A customised fetal growth and birthweight standard for Qatar: a population-based cohort study |
| topic | Biomedical and clinical sciences Reproductive medicine Health sciences Public health birthweight customized growth charts GROW stillbirth fetal growth restriction |