Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties

<p dir="ltr">Aim: To investigate the effect of 20-hydroxyecdysone on steroidogenic pathway genes and plasma progesterone, and its potential impact on vascular functions. Methods: Chimeric mice with humanized liver were treated with 20-hydroxyecdysone for 3 days, and hepatic steroidog...

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Bibliographic Details
Main Author:	Maneera Y Aljaber (18278971) (author)
Other Authors:	Nelson N Orie (18278974) (author), Asmaa Raees (18278977) (author), Suhail Kraiem (18278980) (author), Mashael Al-Jaber (18278983) (author), Waseem Samsam (12204880) (author), Mostafa M Hamza (18278986) (author), David Abraham (36404) (author), Norman M Kneteman (18278989) (author), Alka Beotra (14780368) (author), Vidya Mohamed-Ali (12204895) (author), Mohammed Almaadheed (18278992) (author)
Published:	2022
Subjects:	Biomedical and clinical sciences Clinical sciences Medical biotechnology Pharmacology and pharmaceutical sciences 20-hydroxyecdysone CYP17A1 ecdysteroid hepatic transcriptome humanized liver mesenteric arteriole muscle arteriole progesterone vasodilation voltage-dependent calcium entry
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Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties

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