Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients

<p dir="ltr"><b>Background</b></p><p dir="ltr">Brain tumors are associated with relatively high mortality and morbidity in comparison with their low incidence. Little is known about primary brain tumors in Lebanon, as well as in the Arab world. This...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Said El Hage (19569340) (author)
مؤلفون آخرون: Mohamad Kawtharani (19569343) (author), Sanaa Nabha (18974032) (author), Jad El Masri (19569346) (author), Mohamad Saad (214545) (author)
منشور في: 2021
الموضوعات:
الوسوم: إضافة وسم
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_version_ 1864513506024357888
author Said El Hage (19569340)
author2 Mohamad Kawtharani (19569343)
Sanaa Nabha (18974032)
Jad El Masri (19569346)
Mohamad Saad (214545)
author2_role author
author
author
author
author_facet Said El Hage (19569340)
Mohamad Kawtharani (19569343)
Sanaa Nabha (18974032)
Jad El Masri (19569346)
Mohamad Saad (214545)
author_role author
dc.creator.none.fl_str_mv Said El Hage (19569340)
Mohamad Kawtharani (19569343)
Sanaa Nabha (18974032)
Jad El Masri (19569346)
Mohamad Saad (214545)
dc.date.none.fl_str_mv 2021-09-13T03:00:00Z
dc.identifier.none.fl_str_mv 10.7759/cureus.17918
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Distribution_of_Primary_Brain_Tumor_Subtypes_in_Lebanon_A_Multicenter_Eleven-Year_Study_of_695_Patients/26975554
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Neurosciences
Health sciences
Epidemiology
glioblastoma
meningioma
lebanon
epidemiology
brain neoplasms
dc.title.none.fl_str_mv Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr"><b>Background</b></p><p dir="ltr">Brain tumors are associated with relatively high mortality and morbidity in comparison with their low incidence. Little is known about primary brain tumors in Lebanon, as well as in the Arab world. This study aims to analyze the epidemiology of brain tumors across the Lebanese population.</p><p dir="ltr"><br></p><p dir="ltr"><b>Methods</b></p><p dir="ltr">Data from pathology reports of patients diagnosed with malignant and non-malignant primary brain tumors were collected retrospectively in an eleven-year period (2007-2017) from four medical centers in Lebanon. A total of 695 primary brain tumor cases (61% malignant and 39% non-malignant) were retrieved from different regions across the country.</p><p dir="ltr"><br></p><p dir="ltr"><b>Results</b></p><p dir="ltr">Meningiomas were the most common histology in this sample (29.6%), followed by glioblastomas (25.5%) and oligodendrogliomas (5.9%). Pituitary tumors were only 3.5% of brain tumors. Besides, the most common anatomical locations in malignant and non-malignant tumors were cerebral meninges (29.6%), the "other brain" category (21.3%), and the frontal lobe (11.2%). In children and adolescents, embryonal tumors (21%) were the most common histologies, while glioblastomas and meningiomas accounted for 14.8% and 13.6%, respectively.</p><p dir="ltr"><br></p><p dir="ltr"><b>Conclusion</b></p><p dir="ltr">Lebanon presented a low rate of pituitary tumors and an unusually high percentage of malignant tumors, as well as pediatric glioblastomas and meningiomas. This should raise major concerns for policymakers to detect the possible underlying causes. </p><h2>Other Information</h2><p dir="ltr">Published in: Cureus<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.7759/cureus.17918" target="_blank">https://dx.doi.org/10.7759/cureus.17918</a></p>
eu_rights_str_mv openAccess
id Manara2_9f51990194423c136dc8ee4ba88f45e3
identifier_str_mv 10.7759/cureus.17918
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/26975554
publishDate 2021
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spelling Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 PatientsSaid El Hage (19569340)Mohamad Kawtharani (19569343)Sanaa Nabha (18974032)Jad El Masri (19569346)Mohamad Saad (214545)Biomedical and clinical sciencesNeurosciencesHealth sciencesEpidemiologyglioblastomameningiomalebanonepidemiologybrain neoplasms<p dir="ltr"><b>Background</b></p><p dir="ltr">Brain tumors are associated with relatively high mortality and morbidity in comparison with their low incidence. Little is known about primary brain tumors in Lebanon, as well as in the Arab world. This study aims to analyze the epidemiology of brain tumors across the Lebanese population.</p><p dir="ltr"><br></p><p dir="ltr"><b>Methods</b></p><p dir="ltr">Data from pathology reports of patients diagnosed with malignant and non-malignant primary brain tumors were collected retrospectively in an eleven-year period (2007-2017) from four medical centers in Lebanon. A total of 695 primary brain tumor cases (61% malignant and 39% non-malignant) were retrieved from different regions across the country.</p><p dir="ltr"><br></p><p dir="ltr"><b>Results</b></p><p dir="ltr">Meningiomas were the most common histology in this sample (29.6%), followed by glioblastomas (25.5%) and oligodendrogliomas (5.9%). Pituitary tumors were only 3.5% of brain tumors. Besides, the most common anatomical locations in malignant and non-malignant tumors were cerebral meninges (29.6%), the "other brain" category (21.3%), and the frontal lobe (11.2%). In children and adolescents, embryonal tumors (21%) were the most common histologies, while glioblastomas and meningiomas accounted for 14.8% and 13.6%, respectively.</p><p dir="ltr"><br></p><p dir="ltr"><b>Conclusion</b></p><p dir="ltr">Lebanon presented a low rate of pituitary tumors and an unusually high percentage of malignant tumors, as well as pediatric glioblastomas and meningiomas. This should raise major concerns for policymakers to detect the possible underlying causes. </p><h2>Other Information</h2><p dir="ltr">Published in: Cureus<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.7759/cureus.17918" target="_blank">https://dx.doi.org/10.7759/cureus.17918</a></p>2021-09-13T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.7759/cureus.17918https://figshare.com/articles/journal_contribution/Distribution_of_Primary_Brain_Tumor_Subtypes_in_Lebanon_A_Multicenter_Eleven-Year_Study_of_695_Patients/26975554CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/269755542021-09-13T03:00:00Z
spellingShingle Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
Said El Hage (19569340)
Biomedical and clinical sciences
Neurosciences
Health sciences
Epidemiology
glioblastoma
meningioma
lebanon
epidemiology
brain neoplasms
status_str publishedVersion
title Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
title_full Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
title_fullStr Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
title_full_unstemmed Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
title_short Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
title_sort Distribution of Primary Brain Tumor Subtypes in Lebanon: A Multicenter Eleven-Year Study of 695 Patients
topic Biomedical and clinical sciences
Neurosciences
Health sciences
Epidemiology
glioblastoma
meningioma
lebanon
epidemiology
brain neoplasms