Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy

Accelerated epigenetic aging and DNA methylation alterations in Berardinelli–Seip congenital lipodystrophy

<div><p>Berardinelli–Seip congenital lipodystrophy type 2 (CGL2) is a very rare human genetic disorder with potential significance to the understanding of the pathobiology of aging. CGL2 patients display characteristic progeroid features and suffer from type 2 diabetes, insulin resistanc...

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Main Author: Abeer Qannan (14779192) (author)
Other Authors: Yosra Bejaoui (8552574) (author), Mahmoud Izadi (12899508) (author), Noha A Yousri (17945075) (author), Aleem Razzaq (14779189) (author), Colette Christiansen (11419455) (author), George M Martin (17945078) (author), Jordana T Bell (16220261) (author), Steve Horvath (28847) (author), Junko Oshima (1626) (author), Andre Megarbane (3485465) (author), Johan Ericsson (49714) (author), Ehsan Pourkarimi (541179) (author), Nady El Hajj (686554) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Berardinelli–Seip congenital lipodystrophy
CGL2
type 2 diabetes
gene
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