Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study
<h3>Background</h3><p dir="ltr">Disturbances in sleep duration and quality have been associated with obesity and other metabolic changes. Patients with mental disorders (MD) are known to have more sleep problems, and antipsychotics (AP), used in the treatment of these pat...
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| مؤلفون آخرون: | , , , , , , , , |
| منشور في: |
2019
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إضافة وسم
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| _version_ | 1864513525889630208 |
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| author | Nancy Kiwan (12451992) |
| author2 | Ziyad Mahfoud (15883) Suhaila Ghuloum (796180) Arij Yehya (3095079) Samer Hammoudeh (3095097) Yahya Hani (3095103) Rifka Chamali (12451989) Iman Amro (13996378) Dennis Mook-Kanamori (5520143) Hassen Al-Amin (3095082) |
| author2_role | author author author author author author author author author |
| author_facet | Nancy Kiwan (12451992) Ziyad Mahfoud (15883) Suhaila Ghuloum (796180) Arij Yehya (3095079) Samer Hammoudeh (3095097) Yahya Hani (3095103) Rifka Chamali (12451989) Iman Amro (13996378) Dennis Mook-Kanamori (5520143) Hassen Al-Amin (3095082) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nancy Kiwan (12451992) Ziyad Mahfoud (15883) Suhaila Ghuloum (796180) Arij Yehya (3095079) Samer Hammoudeh (3095097) Yahya Hani (3095103) Rifka Chamali (12451989) Iman Amro (13996378) Dennis Mook-Kanamori (5520143) Hassen Al-Amin (3095082) |
| dc.date.none.fl_str_mv | 2019-07-19T03:00:00Z |
| dc.identifier.none.fl_str_mv | 10.2147/ndt.s207987 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Relationships_between_sleep_patterns_and_metabolic_profile_in_patients_maintained_on_antipsychotics_a_cross-sectional_comparative_study/25331350 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences sleep duration sleep quality metabolic syndrome mental disorders antipsychotics |
| dc.title.none.fl_str_mv | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Disturbances in sleep duration and quality have been associated with obesity and other metabolic changes. Patients with mental disorders (MD) are known to have more sleep problems, and antipsychotics (AP), used in the treatment of these patients, can also cause weight gain. This study aimed to compare the self-reported sleep patterns between psychiatric patients (on or off AP) and controls. We also evaluated the associations between the clinical and metabolic profiles with short or long sleep duration.</p><h3>Methods</h3><p dir="ltr">A total of 339 subjects was recruited: Mentally ill patients maintained on AP for at least six months (MD+AP, n=112), patients not taking AP for at least the last six months before enrollment (MD/noAP, n=101), and non-psychiatry controls (HC, n=126). Multinomial regression analysis was applied to find the predictors of irregular sleep duration in this sample.</p><h3>Results</h3><p dir="ltr">More mentally ill patients (MD+AP and MD/noAP) reported a sleep duration of >8 hrs than HC. Patients from MD/noAP showed more insomnia than HC. Sleep disturbances were significantly more frequent in MD+AP than HC. Participants who reported sleeping >8 hrs had higher body mass index and waist circumference than those who slept <7 hrs.</p><h3>Conclusion</h3><p dir="ltr">Female gender, central obesity and being mentally ill were independently associated with long sleep duration (>8h) in the population of Qatar.</p><h2>Other Information</h2><p dir="ltr">Published in: Neuropsychiatric Disease and Treatment<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/ndt.s207987" target="_blank">https://dx.doi.org/10.2147/ndt.s207987</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_a1311d40eafac98ad610fe74c784c5d0 |
| identifier_str_mv | 10.2147/ndt.s207987 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/25331350 |
| publishDate | 2019 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative studyNancy Kiwan (12451992)Ziyad Mahfoud (15883)Suhaila Ghuloum (796180)Arij Yehya (3095079)Samer Hammoudeh (3095097)Yahya Hani (3095103)Rifka Chamali (12451989)Iman Amro (13996378)Dennis Mook-Kanamori (5520143)Hassen Al-Amin (3095082)Biomedical and clinical sciencesClinical sciencessleep durationsleep qualitymetabolic syndromemental disordersantipsychotics<h3>Background</h3><p dir="ltr">Disturbances in sleep duration and quality have been associated with obesity and other metabolic changes. Patients with mental disorders (MD) are known to have more sleep problems, and antipsychotics (AP), used in the treatment of these patients, can also cause weight gain. This study aimed to compare the self-reported sleep patterns between psychiatric patients (on or off AP) and controls. We also evaluated the associations between the clinical and metabolic profiles with short or long sleep duration.</p><h3>Methods</h3><p dir="ltr">A total of 339 subjects was recruited: Mentally ill patients maintained on AP for at least six months (MD+AP, n=112), patients not taking AP for at least the last six months before enrollment (MD/noAP, n=101), and non-psychiatry controls (HC, n=126). Multinomial regression analysis was applied to find the predictors of irregular sleep duration in this sample.</p><h3>Results</h3><p dir="ltr">More mentally ill patients (MD+AP and MD/noAP) reported a sleep duration of >8 hrs than HC. Patients from MD/noAP showed more insomnia than HC. Sleep disturbances were significantly more frequent in MD+AP than HC. Participants who reported sleeping >8 hrs had higher body mass index and waist circumference than those who slept <7 hrs.</p><h3>Conclusion</h3><p dir="ltr">Female gender, central obesity and being mentally ill were independently associated with long sleep duration (>8h) in the population of Qatar.</p><h2>Other Information</h2><p dir="ltr">Published in: Neuropsychiatric Disease and Treatment<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2147/ndt.s207987" target="_blank">https://dx.doi.org/10.2147/ndt.s207987</a></p>2019-07-19T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2147/ndt.s207987https://figshare.com/articles/journal_contribution/Relationships_between_sleep_patterns_and_metabolic_profile_in_patients_maintained_on_antipsychotics_a_cross-sectional_comparative_study/25331350CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/253313502019-07-19T03:00:00Z |
| spellingShingle | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study Nancy Kiwan (12451992) Biomedical and clinical sciences Clinical sciences sleep duration sleep quality metabolic syndrome mental disorders antipsychotics |
| status_str | publishedVersion |
| title | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| title_full | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| title_fullStr | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| title_full_unstemmed | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| title_short | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| title_sort | Relationships between sleep patterns and metabolic profile in patients maintained on antipsychotics: a cross-sectional comparative study |
| topic | Biomedical and clinical sciences Clinical sciences sleep duration sleep quality metabolic syndrome mental disorders antipsychotics |