The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method
<p>Applying the isoconversional method to data obtained from thermogravimetric analysis (TGA) can provide vital kinetic information. In this work, the thermal decomposition and oxidation of the antidiabetic drug glimepiride is analyzed in the presence of N2 and O2. The study was done with and...
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2022
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| _version_ | 1864513567585206272 |
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| author | Najamus Sahar Riyaz (14151330) |
| author2 | Ismail Badran (1989553) |
| author2_role | author |
| author_facet | Najamus Sahar Riyaz (14151330) Ismail Badran (1989553) |
| author_role | author |
| dc.creator.none.fl_str_mv | Najamus Sahar Riyaz (14151330) Ismail Badran (1989553) |
| dc.date.none.fl_str_mv | 2022-11-22T21:13:49Z |
| dc.identifier.none.fl_str_mv | 10.1007/s10973-022-11304-9 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/The_catalytic_thermo-oxidative_decomposition_of_glimepiride_using_the_isoconversional_method/21597384 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Physical chemistry Condensed matter physics Physical and Theoretical Chemistry Condensed Matter Physics |
| dc.title.none.fl_str_mv | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <p>Applying the isoconversional method to data obtained from thermogravimetric analysis (TGA) can provide vital kinetic information. In this work, the thermal decomposition and oxidation of the antidiabetic drug glimepiride is analyzed in the presence of N2 and O2. The study was done with and without metal oxide catalysts to explore their potential application in solid wastewater upgrading. The analysis was conducted using thermogravimetric analysis. The isoconversional methods of Kissinger–Akahira–Sunose and Friedman were used to estimate the effective activation energies as a function of the extent of conversion (α). Density functional calculations were used to estimate the bond dissociation energies in glimepiride. The Ea values obtained from the Friedman method and the DFT calculations indicate an initial S–N bond breaking in glimepiride. The pre-exponential factor (A) and the kinetic triplet (ΔH‡, ΔS‡, and ΔG‡) are also discussed. When glimepiride oxidation was studied in the presence of the metal oxides, the catalyst activity was found to follow the order $${\text{VO}}_{{2}} > {\text{ CuO }} > {\text{ MnO}}_{{2}} > {\text{ Al}}_{{2}} {\text{O}}_{{3}} > {\text{ TiO}}_{{2}}$$ VO 2 > CuO > MnO 2 > Al 2 O 3 > TiO 2 .</p><h2>Other Information</h2> <p> Published in: Journal of Thermal Analysis and Calorimetry<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10973-022-11304-9" target="_blank">http://dx.doi.org/10.1007/s10973-022-11304-9</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_a2682a0eec2df17cc44907d9c4ee1264 |
| identifier_str_mv | 10.1007/s10973-022-11304-9 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/21597384 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional methodNajamus Sahar Riyaz (14151330)Ismail Badran (1989553)Physical chemistryCondensed matter physicsPhysical and Theoretical ChemistryCondensed Matter Physics<p>Applying the isoconversional method to data obtained from thermogravimetric analysis (TGA) can provide vital kinetic information. In this work, the thermal decomposition and oxidation of the antidiabetic drug glimepiride is analyzed in the presence of N2 and O2. The study was done with and without metal oxide catalysts to explore their potential application in solid wastewater upgrading. The analysis was conducted using thermogravimetric analysis. The isoconversional methods of Kissinger–Akahira–Sunose and Friedman were used to estimate the effective activation energies as a function of the extent of conversion (α). Density functional calculations were used to estimate the bond dissociation energies in glimepiride. The Ea values obtained from the Friedman method and the DFT calculations indicate an initial S–N bond breaking in glimepiride. The pre-exponential factor (A) and the kinetic triplet (ΔH‡, ΔS‡, and ΔG‡) are also discussed. When glimepiride oxidation was studied in the presence of the metal oxides, the catalyst activity was found to follow the order $${\text{VO}}_{{2}} > {\text{ CuO }} > {\text{ MnO}}_{{2}} > {\text{ Al}}_{{2}} {\text{O}}_{{3}} > {\text{ TiO}}_{{2}}$$ VO 2 > CuO > MnO 2 > Al 2 O 3 > TiO 2 .</p><h2>Other Information</h2> <p> Published in: Journal of Thermal Analysis and Calorimetry<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10973-022-11304-9" target="_blank">http://dx.doi.org/10.1007/s10973-022-11304-9</a></p>2022-11-22T21:13:49ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s10973-022-11304-9https://figshare.com/articles/journal_contribution/The_catalytic_thermo-oxidative_decomposition_of_glimepiride_using_the_isoconversional_method/21597384CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/215973842022-11-22T21:13:49Z |
| spellingShingle | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method Najamus Sahar Riyaz (14151330) Physical chemistry Condensed matter physics Physical and Theoretical Chemistry Condensed Matter Physics |
| status_str | publishedVersion |
| title | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| title_full | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| title_fullStr | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| title_full_unstemmed | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| title_short | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| title_sort | The catalytic thermo-oxidative decomposition of glimepiride using the isoconversional method |
| topic | Physical chemistry Condensed matter physics Physical and Theoretical Chemistry Condensed Matter Physics |