Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study
<h3>Background</h3><p dir="ltr">Acute pancreatitis (AP) is a rare but serious complication of intragastric balloon (IGB) therapy. Despite the popularity of IGBs for weight loss, the incidence and risk factors of AP post-IGB insertion are not well understood. This study ai...
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2025
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إضافة وسم
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| _version_ | 1864513513490219008 |
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| author | Yousef Yahia (19756989) |
| author2 | Joud Abuodeh (14777671) Prem Chandra (9072038) Ethar Mohamed (19756992) Anas Zayad (22302712) Leen AbuAfifeh (22302715) |
| author2_role | author author author author author |
| author_facet | Yousef Yahia (19756989) Joud Abuodeh (14777671) Prem Chandra (9072038) Ethar Mohamed (19756992) Anas Zayad (22302712) Leen AbuAfifeh (22302715) |
| author_role | author |
| dc.creator.none.fl_str_mv | Yousef Yahia (19756989) Joud Abuodeh (14777671) Prem Chandra (9072038) Ethar Mohamed (19756992) Anas Zayad (22302712) Leen AbuAfifeh (22302715) |
| dc.date.none.fl_str_mv | 2025-01-14T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1007/s11695-024-07647-x |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Risk_Factors_for_Acute_Pancreatitis_Following_Intragastric_Balloon_Insertion_A_7-Year_Retrospective_Cohort_Study/30196963 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Clinical sciences Intragastric balloon Acute pancreatitis Obesity Weight loss Risk factors Complications Orbera balloon |
| dc.title.none.fl_str_mv | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Background</h3><p dir="ltr">Acute pancreatitis (AP) is a rare but serious complication of intragastric balloon (IGB) therapy. Despite the popularity of IGBs for weight loss, the incidence and risk factors of AP post-IGB insertion are not well understood. This study aimed to identify potential predictors and risk factors of AP in IGB patients.</p><h3>Methods</h3><p dir="ltr">A retrospective time-to-event study was conducted over 7 years, encompassing patients who received IGBs between January 2017 and 2024. Cox regression analyses were performed to identify risk factors. The incidence of AP was evaluated as a secondary outcome. Patients were categorized into the AP and non-AP groups at a 1:3 ratio. The Revised Atlanta Classification was used to diagnose AP.</p><h3>Results</h3><p dir="ltr">Among 450 patients with IGB, 25 developed AP, yielding an incidence of 5.56%. The Orbera balloon was associated with a lower AP risk (HR 0.29, 95% CI: 0.09–0.96; P = 0.042). The median time to AP onset was 40 days. Higher preprocedural BMI and age > 30 years showed a trend toward reduced AP risk, though not statistically significant.</p><h3>Conclusions</h3><p dir="ltr">AP following IGB insertion is uncommon but may be underreported, with substantial variability in onset time. The Orbera balloon demonstrated a protective effect, highlighting the role of balloon type in AP risk. These findings underscore the importance of balloon selection and the need for further prospective studies to confirm these results and optimize AP risk management in IGB patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Obesity Surgery<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11695-024-07647-x" target="_blank">https://dx.doi.org/10.1007/s11695-024-07647-x</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_a7bd322a4aa7cd6c0c4ad35e16cbe246 |
| identifier_str_mv | 10.1007/s11695-024-07647-x |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/30196963 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort StudyYousef Yahia (19756989)Joud Abuodeh (14777671)Prem Chandra (9072038)Ethar Mohamed (19756992)Anas Zayad (22302712)Leen AbuAfifeh (22302715)Biomedical and clinical sciencesClinical sciencesIntragastric balloonAcute pancreatitisObesityWeight lossRisk factorsComplicationsOrbera balloon<h3>Background</h3><p dir="ltr">Acute pancreatitis (AP) is a rare but serious complication of intragastric balloon (IGB) therapy. Despite the popularity of IGBs for weight loss, the incidence and risk factors of AP post-IGB insertion are not well understood. This study aimed to identify potential predictors and risk factors of AP in IGB patients.</p><h3>Methods</h3><p dir="ltr">A retrospective time-to-event study was conducted over 7 years, encompassing patients who received IGBs between January 2017 and 2024. Cox regression analyses were performed to identify risk factors. The incidence of AP was evaluated as a secondary outcome. Patients were categorized into the AP and non-AP groups at a 1:3 ratio. The Revised Atlanta Classification was used to diagnose AP.</p><h3>Results</h3><p dir="ltr">Among 450 patients with IGB, 25 developed AP, yielding an incidence of 5.56%. The Orbera balloon was associated with a lower AP risk (HR 0.29, 95% CI: 0.09–0.96; P = 0.042). The median time to AP onset was 40 days. Higher preprocedural BMI and age > 30 years showed a trend toward reduced AP risk, though not statistically significant.</p><h3>Conclusions</h3><p dir="ltr">AP following IGB insertion is uncommon but may be underreported, with substantial variability in onset time. The Orbera balloon demonstrated a protective effect, highlighting the role of balloon type in AP risk. These findings underscore the importance of balloon selection and the need for further prospective studies to confirm these results and optimize AP risk management in IGB patients.</p><h2>Other Information</h2><p dir="ltr">Published in: Obesity Surgery<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11695-024-07647-x" target="_blank">https://dx.doi.org/10.1007/s11695-024-07647-x</a></p>2025-01-14T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11695-024-07647-xhttps://figshare.com/articles/journal_contribution/Risk_Factors_for_Acute_Pancreatitis_Following_Intragastric_Balloon_Insertion_A_7-Year_Retrospective_Cohort_Study/30196963CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/301969632025-01-14T09:00:00Z |
| spellingShingle | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study Yousef Yahia (19756989) Biomedical and clinical sciences Clinical sciences Intragastric balloon Acute pancreatitis Obesity Weight loss Risk factors Complications Orbera balloon |
| status_str | publishedVersion |
| title | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| title_full | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| title_fullStr | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| title_full_unstemmed | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| title_short | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| title_sort | Risk Factors for Acute Pancreatitis Following Intragastric Balloon Insertion: A 7-Year Retrospective Cohort Study |
| topic | Biomedical and clinical sciences Clinical sciences Intragastric balloon Acute pancreatitis Obesity Weight loss Risk factors Complications Orbera balloon |