Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia

<p dir="ltr">Mucormycosis has multiple clinical phenotypes, which are more common in immunocompromised patients, especially those with diabetes mellitus. Debilitating rhino-orbital-cerebral and pulmonary infections by far represent the most typical clinical phenotypes associated with...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Mohammed A. Alamin (14182297) (author)
مؤلفون آخرون: Mohammed Abdulgayoom (14777791) (author), Sushil Niraula (14777911) (author), Elabbass Abdelmahmuod (14777287) (author), Ashraf O. Ahmed (17191831) (author), Mohammed I. Danjuma (13569767) (author)
منشور في: 2021
الموضوعات:
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author Mohammed A. Alamin (14182297)
author2 Mohammed Abdulgayoom (14777791)
Sushil Niraula (14777911)
Elabbass Abdelmahmuod (14777287)
Ashraf O. Ahmed (17191831)
Mohammed I. Danjuma (13569767)
author2_role author
author
author
author
author
author_facet Mohammed A. Alamin (14182297)
Mohammed Abdulgayoom (14777791)
Sushil Niraula (14777911)
Elabbass Abdelmahmuod (14777287)
Ashraf O. Ahmed (17191831)
Mohammed I. Danjuma (13569767)
author_role author
dc.creator.none.fl_str_mv Mohammed A. Alamin (14182297)
Mohammed Abdulgayoom (14777791)
Sushil Niraula (14777911)
Elabbass Abdelmahmuod (14777287)
Ashraf O. Ahmed (17191831)
Mohammed I. Danjuma (13569767)
dc.date.none.fl_str_mv 2021-09-25T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.idcr.2021.e01293
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Rhino-orbital_Mucormycosis_as_a_complication_of_severe_COVID-19_pneumonia/24340009
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
COVID-19
Mucormycosis
SARS-CoV2
Rhizopus
Black Fungus
dc.title.none.fl_str_mv Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">Mucormycosis has multiple clinical phenotypes, which are more common in immunocompromised patients, especially those with diabetes mellitus. Debilitating rhino-orbital-cerebral and pulmonary infections by far represent the most typical clinical phenotypes associated with these fungi. Mucormycosis is an uncommon infection; however, there have been isolated sporadic tiny outbreaks around the world. With the substantial increase in COVID-19 cases in India, there is a parallel increase in the number of cases of Mucormycosis. A few reports raising unusual concomitant mucormycosis in COVID-19 patients have raised a possible association between the two diseases.</p><p dir="ltr">We report a 59-year-old male with an established history of uncontrolled diabetes mellitus admitted to the hospital with severe COVID-19 pneumonia (severity ascertained according to WHO classification) treated with steroids and discharged home following full recovery. However, one week later, he presented with right eye ophthalmoplegia and complete loss of vision, which was subsequently established as orbital Mucormycosis.</p><p dir="ltr">This case highlights the need for heightened awareness of this atypical secondary infection (especially systemic mycosis) in patients recovering from COVID-19 infection.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01293" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01293</a></p>
eu_rights_str_mv openAccess
id Manara2_a82f521596b6cd8fc98397b64f72e876
identifier_str_mv 10.1016/j.idcr.2021.e01293
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24340009
publishDate 2021
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spelling Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumoniaMohammed A. Alamin (14182297)Mohammed Abdulgayoom (14777791)Sushil Niraula (14777911)Elabbass Abdelmahmuod (14777287)Ashraf O. Ahmed (17191831)Mohammed I. Danjuma (13569767)Biomedical and clinical sciencesCardiovascular medicine and haematologyClinical sciencesCOVID-19MucormycosisSARS-CoV2RhizopusBlack Fungus<p dir="ltr">Mucormycosis has multiple clinical phenotypes, which are more common in immunocompromised patients, especially those with diabetes mellitus. Debilitating rhino-orbital-cerebral and pulmonary infections by far represent the most typical clinical phenotypes associated with these fungi. Mucormycosis is an uncommon infection; however, there have been isolated sporadic tiny outbreaks around the world. With the substantial increase in COVID-19 cases in India, there is a parallel increase in the number of cases of Mucormycosis. A few reports raising unusual concomitant mucormycosis in COVID-19 patients have raised a possible association between the two diseases.</p><p dir="ltr">We report a 59-year-old male with an established history of uncontrolled diabetes mellitus admitted to the hospital with severe COVID-19 pneumonia (severity ascertained according to WHO classification) treated with steroids and discharged home following full recovery. However, one week later, he presented with right eye ophthalmoplegia and complete loss of vision, which was subsequently established as orbital Mucormycosis.</p><p dir="ltr">This case highlights the need for heightened awareness of this atypical secondary infection (especially systemic mycosis) in patients recovering from COVID-19 infection.</p><h2>Other Information</h2><p dir="ltr">Published in: IDCases<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2021.e01293" target="_blank">https://dx.doi.org/10.1016/j.idcr.2021.e01293</a></p>2021-09-25T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.idcr.2021.e01293https://figshare.com/articles/journal_contribution/Rhino-orbital_Mucormycosis_as_a_complication_of_severe_COVID-19_pneumonia/24340009CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/243400092021-09-25T00:00:00Z
spellingShingle Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
Mohammed A. Alamin (14182297)
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
COVID-19
Mucormycosis
SARS-CoV2
Rhizopus
Black Fungus
status_str publishedVersion
title Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
title_full Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
title_fullStr Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
title_full_unstemmed Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
title_short Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
title_sort Rhino-orbital Mucormycosis as a complication of severe COVID-19 pneumonia
topic Biomedical and clinical sciences
Cardiovascular medicine and haematology
Clinical sciences
COVID-19
Mucormycosis
SARS-CoV2
Rhizopus
Black Fungus