Loss of the yeast transporter Agp2 upregulates the pleiotropic drug-resistant pump Pdr5 and confers resistance to the protein synthesis inhibitor cycloheximide
<p dir="ltr">The transmembrane protein Agp2, initially shown as a transporter of L-carnitine, mediates the high-affinity transport of polyamines and the anticancer drug bleomycin-A5. Cells lacking Agp2 are hyper-resistant to polyamine and bleomycin-A5. In these earlier studies, we sh...
محفوظ في:
| المؤلف الرئيسي: | Yusra Manzoor (18599180) (author) |
|---|---|
| مؤلفون آخرون: | Mustapha Aouida (417652) (author), Ramya Ramadoss (16003318) (author), Balasubramanian Moovarkumudalvan (18300811) (author), Nisar Ahmed (584617) (author), Abdallah Alhaj Sulaiman (17777421) (author), Ashima Mohanty (18599183) (author), Reem Ali (9913494) (author), Borbala Mifsud (3907267) (author), Dindial Ramotar (208416) (author) |
| منشور في: |
2024
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| الموضوعات: | |
| الوسوم: |
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مواد مشابهة
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