Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice

<div><p>Accumulation of amyloid-β plaques and tau contribute to the pathogenesis of Alzheimer’s disease (AD), but it is unclear whether targeting tau pathology by antioxidants independently of amyloid-β causes beneficial effects on memory and neuropsychiatric symptoms. Selenium, an essen...

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Bibliographic Details
Main Author: Ann Van der Jeugd (18629695) (author)
Other Authors: Arnaldo Parra-Damas (230723) (author), Raquel Baeta-Corral (18629698) (author), Carlos M. Soto-Faguás (18629701) (author), Tariq Ahmed (5768081) (author), Frank M. LaFerla (11991116) (author), Lydia Giménez-Llort (447668) (author), Rudi D’Hooge (412153) (author), Carlos A. Saura (11666536) (author)
Published: 2018
Subjects:
Biomedical and clinical sciences
Neurosciences
Alzheimer's disease (AD)
Amyloid-β plaques
Tau pathology
Neuropathology
Selenium
Antioxidants
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