Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

<p dir="ltr">Aggregation of α-synuclein (α-syn) has been implicated in multiple neurodegenerative disorders including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), collectively grouped as synucleinopathies. Recently, recombinant antibody...

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Bibliographic Details
Main Author: Vijay Gupta (209146) (author)
Other Authors: Indulekha P. Sudhakaran (9611154) (author), Zeyaul Islam (5867387) (author), Nishant N. Vaikath (2901785) (author), Issam Hmila (9239059) (author), Tamas Lukacsovich (23182) (author), Prasanna R. Kolatkar (124118) (author), Omar M. A. El-Agnaf (8809331) (author)
Published: 2020
Subjects:
Biomedical and clinical sciences
Clinical sciences
Medical biotechnology
Neurosciences
Urea
Protein denaturation
Monomers
Protein structure
Protein folding
Protein expression
Enzyme-linked immunoassays
Imidazole
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