Varicella-Zoster meningitis with normal CSF cellularity: A rare case report

<p>Varicella-zoster virus (VZV) meningitis is a one of the manifestations of VZV reactivation which usually presents with fever, headache, and is sometimes preceded by a dermatomal vesicular rash. CSF analysis is the cornerstone investigation in helping to identify the causative organism or in...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Bana Sabbagh (16748719) (author)
مؤلفون آخرون: Mohammed Najdat Seijari (17563263) (author), Mhd Kutaiba Albuni (11721777) (author), Munsef Barakat (17563266) (author), Gamal B. Alfitori (17563269) (author)
منشور في: 2022
الموضوعات:
الوسوم: إضافة وسم
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author Bana Sabbagh (16748719)
author2 Mohammed Najdat Seijari (17563263)
Mhd Kutaiba Albuni (11721777)
Munsef Barakat (17563266)
Gamal B. Alfitori (17563269)
author2_role author
author
author
author
author_facet Bana Sabbagh (16748719)
Mohammed Najdat Seijari (17563263)
Mhd Kutaiba Albuni (11721777)
Munsef Barakat (17563266)
Gamal B. Alfitori (17563269)
author_role author
dc.creator.none.fl_str_mv Bana Sabbagh (16748719)
Mohammed Najdat Seijari (17563263)
Mhd Kutaiba Albuni (11721777)
Munsef Barakat (17563266)
Gamal B. Alfitori (17563269)
dc.date.none.fl_str_mv 2022-01-01T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.idcr.2022.e01484
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Varicella-Zoster_meningitis_with_normal_CSF_cellularity_A_rare_case_report/24745773
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Clinical sciences
Neurosciences
Aseptic meningitis
Varicella-Zoster
CSF analysis
dc.title.none.fl_str_mv Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p>Varicella-zoster virus (VZV) meningitis is a one of the manifestations of VZV reactivation which usually presents with fever, headache, and is sometimes preceded by a dermatomal vesicular rash. CSF analysis is the cornerstone investigation in helping to identify the causative organism or in orienting the physician toward a possible agent. CSF analysis in Viral meningitis usually reveals lymphocytic pleocytosis. However, normal CSF analysis with viral meningitis -despite being rare- has been reported especially with bacterial causes. Therefore, a first CSF puncture cannot rule out infection and a second one might be warranted if there is still high suspicion of viral meningitis with no diagnosis made by PCR. Here we present a case of an 89-year-old female who had signs and symptoms of meningitis with normal CSF analysis. However, polymerase chain reaction (PCR) was positive for VZV. The patient was treated accordingly, and she recovered fully.</p><h2>Other Information</h2> <p> Published in: IDCases<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2022.e01484" target="_blank">https://dx.doi.org/10.1016/j.idcr.2022.e01484</a></p>
eu_rights_str_mv openAccess
id Manara2_abfba2fe52f797b455b96558aa1ff185
identifier_str_mv 10.1016/j.idcr.2022.e01484
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24745773
publishDate 2022
repository.mail.fl_str_mv
repository.name.fl_str_mv
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rights_invalid_str_mv CC BY 4.0
spelling Varicella-Zoster meningitis with normal CSF cellularity: A rare case reportBana Sabbagh (16748719)Mohammed Najdat Seijari (17563263)Mhd Kutaiba Albuni (11721777)Munsef Barakat (17563266)Gamal B. Alfitori (17563269)Biomedical and clinical sciencesClinical sciencesNeurosciencesAseptic meningitisVaricella-ZosterCSF analysis<p>Varicella-zoster virus (VZV) meningitis is a one of the manifestations of VZV reactivation which usually presents with fever, headache, and is sometimes preceded by a dermatomal vesicular rash. CSF analysis is the cornerstone investigation in helping to identify the causative organism or in orienting the physician toward a possible agent. CSF analysis in Viral meningitis usually reveals lymphocytic pleocytosis. However, normal CSF analysis with viral meningitis -despite being rare- has been reported especially with bacterial causes. Therefore, a first CSF puncture cannot rule out infection and a second one might be warranted if there is still high suspicion of viral meningitis with no diagnosis made by PCR. Here we present a case of an 89-year-old female who had signs and symptoms of meningitis with normal CSF analysis. However, polymerase chain reaction (PCR) was positive for VZV. The patient was treated accordingly, and she recovered fully.</p><h2>Other Information</h2> <p> Published in: IDCases<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.idcr.2022.e01484" target="_blank">https://dx.doi.org/10.1016/j.idcr.2022.e01484</a></p>2022-01-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.idcr.2022.e01484https://figshare.com/articles/journal_contribution/Varicella-Zoster_meningitis_with_normal_CSF_cellularity_A_rare_case_report/24745773CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/247457732022-01-01T00:00:00Z
spellingShingle Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
Bana Sabbagh (16748719)
Biomedical and clinical sciences
Clinical sciences
Neurosciences
Aseptic meningitis
Varicella-Zoster
CSF analysis
status_str publishedVersion
title Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
title_full Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
title_fullStr Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
title_full_unstemmed Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
title_short Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
title_sort Varicella-Zoster meningitis with normal CSF cellularity: A rare case report
topic Biomedical and clinical sciences
Clinical sciences
Neurosciences
Aseptic meningitis
Varicella-Zoster
CSF analysis