Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform

<h3>Purpose</h3><p dir="ltr">The interleukin-7 receptor (IL-7R) is primarily expressed on lymphoid cells and plays a crucial role in the development, proliferation, and survival of T cells. Autosomal recessive mutations that disrupt IL-7Rα chain expression give rise to a...

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Bibliographic Details
Main Author:	Rafah Mackeh (14151225) (author)
Other Authors:	Yasmin El Bsat (19239436) (author), Asha Elmi (9592371) (author), Hani Bibawi (19239439) (author), Mohammed Yousuf Karim (8602092) (author), Amel Hassan (14151231) (author), Bernice Lo (3441317) (author)
Published:	2024
Subjects:	Biological sciences Genetics Biomedical and clinical sciences Clinical sciences Primary immunodeficiency (PID) Severe Combined Immunodeficiency (SCID) IL-7Rα deficiency IL-7Rα exon 6 Altered splicing Synonymous variant
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Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform

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