Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes

Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes

<p dir="ltr">Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important roles in adipogenesis and inflammation. The aim of thi...

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Bibliographic Details
Main Author: Layla Al-Mansoori (9522518) (author)
Other Authors: Hend Al-Jaber (9522521) (author), Aisha Y. Madani (14152911) (author), Nayef A. Mazloum (7355087) (author), Abdelali Agouni (181926) (author), Manjunath Ramanjaneya (519259) (author), Abdul-Badi Abou-Samra (3411167) (author), Mohamed A. Elrayess (7956179) (author)
Published: 2020
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Clinical sciences
Pharmacology and pharmaceutical sciences
GATA-3 suppression
Adipogenesis
Inflammation
Insulin resistance
Target validation
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