ABC transporter inhibition by beauvericin partially overcomes drug resistance in <i>Leishmania tropica</i>

ABC transporter inhibition by beauvericin partially overcomes drug resistance in <i>Leishmania tropica</i>

<p dir="ltr">Leishmaniasis is a neglected tropical disease infecting the world’s poorest populations. Miltefosine (ML) remains the primary oral drug against the cutaneous form of leishmaniasis. The ATP-binding cassette (ABC) transporters are key players in the xenobiotic efflux, and...

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Bibliographic Details
Main Author: Charbel Al Khoury (13167975) (author)
Other Authors: Sergio Thoumi (19255920) (author), Sima Tokajian (3559616) (author), Aia Sinno (19255921) (author), Georges Nemer (14152947) (author), Mark El Beyrouthy (19255923) (author), Kelven Rahy (19255926) (author)
Published: 2024
Subjects:
Biomedical and clinical sciences
Medical microbiology
Pharmacology and pharmaceutical sciences
Chemical sciences
Medicinal and biomolecular chemistry
Leishmania tropica
leishmaniasis
drug resistance
ABC transporter
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