Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer
<h3>Introduction</h3><p dir="ltr">Therapy-related myeloid neoplasms result from exposure to specific agents such as ionizing radiation, chemotherapy, and immunosuppressive agents. Radioactive iodine plays an essential role in managing differentiated thyroid cancers such a...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | |
| منشور في: |
2022
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513548687769600 |
|---|---|
| author | Yousef Mohammed Ali Hailan (14777536) |
| author2 | Mohamed A. Yassin (8361183) |
| author2_role | author |
| author_facet | Yousef Mohammed Ali Hailan (14777536) Mohamed A. Yassin (8361183) |
| author_role | author |
| dc.creator.none.fl_str_mv | Yousef Mohammed Ali Hailan (14777536) Mohamed A. Yassin (8361183) |
| dc.date.none.fl_str_mv | 2022-04-07T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1097/md9.0000000000000237 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Chronic_myeloid_leukemia_following_low_dose_radioactive_iodine_I_sup_131_sup_for_treatment_of_papillary_thyroid_cancer/29045477 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences CML I131 papillary thyroid cancer radioiodine therapy related leukemia |
| dc.title.none.fl_str_mv | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Introduction</h3><p dir="ltr">Therapy-related myeloid neoplasms result from exposure to specific agents such as ionizing radiation, chemotherapy, and immunosuppressive agents. Radioactive iodine plays an essential role in managing differentiated thyroid cancers such as papillary thyroid carcinoma to reduce the risk of recurrence.</p><h3>Patient concerns</h3><p dir="ltr">We present the case of a 48-year-old Bangladeshi male with a history of papillary thyroid cancer after total thyroidectomy and radiofrequency ablation therapy with I<sup>131</sup> (32.6 mCi) who presented with abdominal pain and was found to have chronic myeloid leukemia 3 years after treatment for papillary thyroid cancer.</p><h3>Diagnosis</h3><p dir="ltr">Chronic myeloid leukemia secondary to low-dose radioactive iodine (I<sup>131</sup>).</p><h3>Interventions</h3><p dir="ltr">The patient was started on dasatinib (140 mg/day).</p><h3>Outcomes</h3><p dir="ltr">The patient is currently being prepared for bone marrow transplantation by donor search and HLA typing.</p><h3>Conclusion</h3><p dir="ltr">This case emphasizes the importance of considering the leukemogenic effects of I<sup>131</sup>.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine: Case Reports and Study Protocols<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1097/md9.0000000000000237" target="_blank">https://dx.doi.org/10.1097/md9.0000000000000237</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_aebf3cfe2c81e07ac5807d7c1e96caa9 |
| identifier_str_mv | 10.1097/md9.0000000000000237 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/29045477 |
| publishDate | 2022 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancerYousef Mohammed Ali Hailan (14777536)Mohamed A. Yassin (8361183)Biomedical and clinical sciencesOncology and carcinogenesisPharmacology and pharmaceutical sciencesCMLI131papillary thyroid cancerradioiodinetherapy related leukemia<h3>Introduction</h3><p dir="ltr">Therapy-related myeloid neoplasms result from exposure to specific agents such as ionizing radiation, chemotherapy, and immunosuppressive agents. Radioactive iodine plays an essential role in managing differentiated thyroid cancers such as papillary thyroid carcinoma to reduce the risk of recurrence.</p><h3>Patient concerns</h3><p dir="ltr">We present the case of a 48-year-old Bangladeshi male with a history of papillary thyroid cancer after total thyroidectomy and radiofrequency ablation therapy with I<sup>131</sup> (32.6 mCi) who presented with abdominal pain and was found to have chronic myeloid leukemia 3 years after treatment for papillary thyroid cancer.</p><h3>Diagnosis</h3><p dir="ltr">Chronic myeloid leukemia secondary to low-dose radioactive iodine (I<sup>131</sup>).</p><h3>Interventions</h3><p dir="ltr">The patient was started on dasatinib (140 mg/day).</p><h3>Outcomes</h3><p dir="ltr">The patient is currently being prepared for bone marrow transplantation by donor search and HLA typing.</p><h3>Conclusion</h3><p dir="ltr">This case emphasizes the importance of considering the leukemogenic effects of I<sup>131</sup>.</p><h2>Other Information</h2><p dir="ltr">Published in: Medicine: Case Reports and Study Protocols<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1097/md9.0000000000000237" target="_blank">https://dx.doi.org/10.1097/md9.0000000000000237</a></p>2022-04-07T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1097/md9.0000000000000237https://figshare.com/articles/journal_contribution/Chronic_myeloid_leukemia_following_low_dose_radioactive_iodine_I_sup_131_sup_for_treatment_of_papillary_thyroid_cancer/29045477CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/290454772022-04-07T09:00:00Z |
| spellingShingle | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer Yousef Mohammed Ali Hailan (14777536) Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences CML I131 papillary thyroid cancer radioiodine therapy related leukemia |
| status_str | publishedVersion |
| title | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| title_full | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| title_fullStr | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| title_full_unstemmed | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| title_short | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| title_sort | Chronic myeloid leukemia following low dose radioactive iodine (I<sup>131</sup>) for treatment of papillary thyroid cancer |
| topic | Biomedical and clinical sciences Oncology and carcinogenesis Pharmacology and pharmaceutical sciences CML I131 papillary thyroid cancer radioiodine therapy related leukemia |