The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis

<h3>Background</h3><p dir="ltr">Depression is a common mental disorder characterized by disturbances in mood, thoughts, or behaviors. Serious games, which are games that have a purpose other than entertainment, have been used as a nonpharmacological therapeutic interventi...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Alaa Abd-Alrazaq (17430900) (author)
مؤلفون آخرون: Eiman Al-Jafar (17541837) (author), Mohannad Alajlani (9392676) (author), Carla Toro (18434052) (author), Dari Alhuwail (6497858) (author), Arfan Ahmed (17541309) (author), Shuja Mohd Reagu (12051406) (author), Najeeb Al-Shorbaji (18434055) (author), Mowafa Househ (9154124) (author)
منشور في: 2022
الموضوعات:
الوسوم: إضافة وسم
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author Alaa Abd-Alrazaq (17430900)
author2 Eiman Al-Jafar (17541837)
Mohannad Alajlani (9392676)
Carla Toro (18434052)
Dari Alhuwail (6497858)
Arfan Ahmed (17541309)
Shuja Mohd Reagu (12051406)
Najeeb Al-Shorbaji (18434055)
Mowafa Househ (9154124)
author2_role author
author
author
author
author
author
author
author
author_facet Alaa Abd-Alrazaq (17430900)
Eiman Al-Jafar (17541837)
Mohannad Alajlani (9392676)
Carla Toro (18434052)
Dari Alhuwail (6497858)
Arfan Ahmed (17541309)
Shuja Mohd Reagu (12051406)
Najeeb Al-Shorbaji (18434055)
Mowafa Househ (9154124)
author_role author
dc.creator.none.fl_str_mv Alaa Abd-Alrazaq (17430900)
Eiman Al-Jafar (17541837)
Mohannad Alajlani (9392676)
Carla Toro (18434052)
Dari Alhuwail (6497858)
Arfan Ahmed (17541309)
Shuja Mohd Reagu (12051406)
Najeeb Al-Shorbaji (18434055)
Mowafa Househ (9154124)
dc.date.none.fl_str_mv 2022-01-14T03:00:00Z
dc.identifier.none.fl_str_mv 10.2196/32331
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/The_Effectiveness_of_Serious_Games_for_Alleviating_Depression_Systematic_Review_and_Meta-analysis/25679835
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Psychology
Cognitive and computational psychology
serious games
exergames
depression
cognitive behavioral therapy
systematic reviews
meta-analysis
dc.title.none.fl_str_mv The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Depression is a common mental disorder characterized by disturbances in mood, thoughts, or behaviors. Serious games, which are games that have a purpose other than entertainment, have been used as a nonpharmacological therapeutic intervention for depression. Previous systematic reviews have summarized evidence of effectiveness of serious games in reducing depression symptoms; however, they are limited by design and methodological shortcomings.</p><h3>Objective</h3><p dir="ltr">This study aimed to assess the effectiveness of serious games in alleviating depression by summarizing and pooling the results of previous studies.</p><h3>Methods</h3><p dir="ltr">A systematic review of randomized controlled trials (RCTs) was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The search sources included 6 bibliographic databases (eg, MEDLINE, PsycINFO, IEEE Xplore), the search engine “Google Scholar,” and backward and forward reference list checking of the included studies and relevant reviews. Two reviewers independently carried out the study selection, data extraction, risk of bias assessment, and quality of evidence appraisal. Results of the included studies were synthesized narratively and statistically, as appropriate, according to the type of serious games (ie, exergames or computerized cognitive behavioral therapy [CBT] games).</p><h3>Results</h3><p dir="ltr">From an initial 966 citations retrieved, 27 studies met the eligibility criteria, and 16 studies were eventually included in meta-analyses. Very low-quality evidence from 7 RCTs showed no statistically significant effect of exergames on the severity of depressive symptoms as compared with conventional exercises (P=.12). Very low-quality evidence from 5 RCTs showed a statistically and clinically significant difference in the severity of depressive symptoms (P=.004) between exergame and control groups, favoring exergames over no intervention. Very low-quality evidence from 7 RCTs showed a statistically and clinically significant effect of computerized CBT games on the severity of depressive symptoms in comparison with no intervention (P=.003).</p><h3>Conclusions</h3><p dir="ltr">Serious games have the potential to alleviate depression as other active interventions do. However, we could not draw definitive conclusions regarding the effectiveness of serious games due to the high risk of bias in the individual studies examined and the low quality of meta-analyzed evidence. Therefore, we recommend that health care providers consider offering serious games as an adjunct to existing interventions until further, more robust evidence is available. Future studies should assess the effectiveness of serious games that are designed specifically to alleviate depression and deliver other therapeutic modalities, recruit participants with depression, and avoid biases by following recommended guidelines for conducting and reporting RCTs.</p><h3>Trial Registration</h3><p dir="ltr">PROSPERO International Prospective Register of Systematic Reviews CRD42021232969; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=232969</p><h2>Other Information</h2><p dir="ltr">Published in: JMIR Serious Games<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/32331" target="_blank">https://dx.doi.org/10.2196/32331</a></p>
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spelling The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysisAlaa Abd-Alrazaq (17430900)Eiman Al-Jafar (17541837)Mohannad Alajlani (9392676)Carla Toro (18434052)Dari Alhuwail (6497858)Arfan Ahmed (17541309)Shuja Mohd Reagu (12051406)Najeeb Al-Shorbaji (18434055)Mowafa Househ (9154124)PsychologyCognitive and computational psychologyserious gamesexergamesdepressioncognitive behavioral therapysystematic reviewsmeta-analysis<h3>Background</h3><p dir="ltr">Depression is a common mental disorder characterized by disturbances in mood, thoughts, or behaviors. Serious games, which are games that have a purpose other than entertainment, have been used as a nonpharmacological therapeutic intervention for depression. Previous systematic reviews have summarized evidence of effectiveness of serious games in reducing depression symptoms; however, they are limited by design and methodological shortcomings.</p><h3>Objective</h3><p dir="ltr">This study aimed to assess the effectiveness of serious games in alleviating depression by summarizing and pooling the results of previous studies.</p><h3>Methods</h3><p dir="ltr">A systematic review of randomized controlled trials (RCTs) was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The search sources included 6 bibliographic databases (eg, MEDLINE, PsycINFO, IEEE Xplore), the search engine “Google Scholar,” and backward and forward reference list checking of the included studies and relevant reviews. Two reviewers independently carried out the study selection, data extraction, risk of bias assessment, and quality of evidence appraisal. Results of the included studies were synthesized narratively and statistically, as appropriate, according to the type of serious games (ie, exergames or computerized cognitive behavioral therapy [CBT] games).</p><h3>Results</h3><p dir="ltr">From an initial 966 citations retrieved, 27 studies met the eligibility criteria, and 16 studies were eventually included in meta-analyses. Very low-quality evidence from 7 RCTs showed no statistically significant effect of exergames on the severity of depressive symptoms as compared with conventional exercises (P=.12). Very low-quality evidence from 5 RCTs showed a statistically and clinically significant difference in the severity of depressive symptoms (P=.004) between exergame and control groups, favoring exergames over no intervention. Very low-quality evidence from 7 RCTs showed a statistically and clinically significant effect of computerized CBT games on the severity of depressive symptoms in comparison with no intervention (P=.003).</p><h3>Conclusions</h3><p dir="ltr">Serious games have the potential to alleviate depression as other active interventions do. However, we could not draw definitive conclusions regarding the effectiveness of serious games due to the high risk of bias in the individual studies examined and the low quality of meta-analyzed evidence. Therefore, we recommend that health care providers consider offering serious games as an adjunct to existing interventions until further, more robust evidence is available. Future studies should assess the effectiveness of serious games that are designed specifically to alleviate depression and deliver other therapeutic modalities, recruit participants with depression, and avoid biases by following recommended guidelines for conducting and reporting RCTs.</p><h3>Trial Registration</h3><p dir="ltr">PROSPERO International Prospective Register of Systematic Reviews CRD42021232969; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=232969</p><h2>Other Information</h2><p dir="ltr">Published in: JMIR Serious Games<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.2196/32331" target="_blank">https://dx.doi.org/10.2196/32331</a></p>2022-01-14T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.2196/32331https://figshare.com/articles/journal_contribution/The_Effectiveness_of_Serious_Games_for_Alleviating_Depression_Systematic_Review_and_Meta-analysis/25679835CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/256798352022-01-14T03:00:00Z
spellingShingle The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
Alaa Abd-Alrazaq (17430900)
Psychology
Cognitive and computational psychology
serious games
exergames
depression
cognitive behavioral therapy
systematic reviews
meta-analysis
status_str publishedVersion
title The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
title_full The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
title_fullStr The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
title_full_unstemmed The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
title_short The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
title_sort The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis
topic Psychology
Cognitive and computational psychology
serious games
exergames
depression
cognitive behavioral therapy
systematic reviews
meta-analysis