Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone

Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone

<p dir="ltr">Persistent ER stress, mitochondrial dysfunction and failure of the heat shock response (HSR) are fundamental hallmarks of insulin resistance (IR); one of the early core metabolic aberrations that leads to type 2 diabetes (T2D). The antioxidant α-lipoic acid (ALA) has bee...

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Bibliographic Details
Main Author: Abdoulaye Diane (14152749) (author)
Other Authors: Naela Mahmoud (18566719) (author), Ilham Bensmail (12204845) (author), Namat Khattab (14152752) (author), Hanan A. Abunada (18566722) (author), Mohammed Dehbi (309033) (author)
Published: 2020
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Clinical sciences
Insulin resistance
Type 2 diabetes
Metabolic stress
Glucose uptake
Antioxidant
Molecular mechanisms
siRNA transfection
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