CRISPR-Cas Controls Cryptic Prophages

CRISPR-Cas Controls Cryptic Prophages

<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. Specifically...

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Bibliographic Details
Main Author: Sooyeon Song (4891132) (author)
Other Authors: Ekaterina Semenova (13071) (author), Konstantin Severinov (11333) (author), Laura Fernández-García (3854878) (author), Michael J. Benedik (2353612) (author), Toshinari Maeda (76008) (author), Thomas K. Wood (49042) (author)
Published: 2022
Subjects:
Chemical sciences
Inorganic chemistry
Organic chemistry
Theoretical and computational chemistry
CRISPR-Cas
persisters
cryptic prophage
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