Role of HMGB1 and its associated signaling pathways in human malignancies

Role of HMGB1 and its associated signaling pathways in human malignancies

<p dir="ltr">The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 has been reported to regulate several signaling...

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Bibliographic Details
Main Author: Sourour Idoudi (14153457) (author)
Other Authors: Takwa Bedhiafi (14153460) (author), Shona Pedersen (2792278) (author), Mohamed Elahtem (17431002) (author), Izzaldin Alremawi (17431005) (author), Sabah Akhtar (5809925) (author), Said Dermime (79420) (author), Maysaloun Merhi (4246147) (author), Shahab Uddin (154400) (author)
Published: 2023
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
HMGB1
Signaling pathways
cancer therapy
Immune checkpoint blockade
Clinical applications
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