Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months

<p dir="ltr">We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 d...

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Main Author: Laith J. Abu-Raddad (9262524) (author)
Other Authors: Hiam Chemaitelly (439114) (author), Joel A. Malek (10327973) (author), Ayeda A. Ahmed (11847025) (author), Yasmin A. Mohamoud (10671696) (author), Shameem Younuskunju (6850097) (author), Zaina Al Kanaani (5018198) (author), Abdullatif Al Khal (12024468) (author), Einas Al Kuwari (12024471) (author), Adeel A. Butt (3697705) (author), Peter Coyle (787159) (author), Andrew Jeremijenko (11506565) (author), Anvar Hassan Kaleeckal (11847034) (author), Ali Nizar Latif (11570540) (author), Riyazuddin Mohammad Shaik (11847037) (author), Hanan F. Abdul Rahim (9330201) (author), Hadi M. Yassine (4675846) (author), Mohamed G. Al Kuwari (12024474) (author), Hamad Eid Al Romaihi (12024477) (author), Mohamed H. Al-Thani (11847049) (author), Roberto Bertollini (9538620) (author)
Published: 2021
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author Laith J. Abu-Raddad (9262524)
author2 Hiam Chemaitelly (439114)
Joel A. Malek (10327973)
Ayeda A. Ahmed (11847025)
Yasmin A. Mohamoud (10671696)
Shameem Younuskunju (6850097)
Zaina Al Kanaani (5018198)
Abdullatif Al Khal (12024468)
Einas Al Kuwari (12024471)
Adeel A. Butt (3697705)
Peter Coyle (787159)
Andrew Jeremijenko (11506565)
Anvar Hassan Kaleeckal (11847034)
Ali Nizar Latif (11570540)
Riyazuddin Mohammad Shaik (11847037)
Hanan F. Abdul Rahim (9330201)
Hadi M. Yassine (4675846)
Mohamed G. Al Kuwari (12024474)
Hamad Eid Al Romaihi (12024477)
Mohamed H. Al-Thani (11847049)
Roberto Bertollini (9538620)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
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author
author_facet Laith J. Abu-Raddad (9262524)
Hiam Chemaitelly (439114)
Joel A. Malek (10327973)
Ayeda A. Ahmed (11847025)
Yasmin A. Mohamoud (10671696)
Shameem Younuskunju (6850097)
Zaina Al Kanaani (5018198)
Abdullatif Al Khal (12024468)
Einas Al Kuwari (12024471)
Adeel A. Butt (3697705)
Peter Coyle (787159)
Andrew Jeremijenko (11506565)
Anvar Hassan Kaleeckal (11847034)
Ali Nizar Latif (11570540)
Riyazuddin Mohammad Shaik (11847037)
Hanan F. Abdul Rahim (9330201)
Hadi M. Yassine (4675846)
Mohamed G. Al Kuwari (12024474)
Hamad Eid Al Romaihi (12024477)
Mohamed H. Al-Thani (11847049)
Roberto Bertollini (9538620)
author_role author
dc.creator.none.fl_str_mv Laith J. Abu-Raddad (9262524)
Hiam Chemaitelly (439114)
Joel A. Malek (10327973)
Ayeda A. Ahmed (11847025)
Yasmin A. Mohamoud (10671696)
Shameem Younuskunju (6850097)
Zaina Al Kanaani (5018198)
Abdullatif Al Khal (12024468)
Einas Al Kuwari (12024471)
Adeel A. Butt (3697705)
Peter Coyle (787159)
Andrew Jeremijenko (11506565)
Anvar Hassan Kaleeckal (11847034)
Ali Nizar Latif (11570540)
Riyazuddin Mohammad Shaik (11847037)
Hanan F. Abdul Rahim (9330201)
Hadi M. Yassine (4675846)
Mohamed G. Al Kuwari (12024474)
Hamad Eid Al Romaihi (12024477)
Mohamed H. Al-Thani (11847049)
Roberto Bertollini (9538620)
dc.date.none.fl_str_mv 2021-03-01T00:00:00Z
dc.identifier.none.fl_str_mv 10.1016/j.meegid.2020.104684
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Two_prolonged_viremic_SARS-CoV-2_infections_with_conserved_viral_genome_for_two_months/24087663
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
SARS-CoV-2
COVID-19
Epidemiology
Infection
Genome
Infectious period
dc.title.none.fl_str_mv Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <p dir="ltr">We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons.</p><h2>Other Information</h2><p dir="ltr">Published in: Infection, Genetics and Evolution<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.meegid.2020.104684" target="_blank">https://dx.doi.org/10.1016/j.meegid.2020.104684</a></p>
eu_rights_str_mv openAccess
id Manara2_b336b597f0f113ce2522f1694194fd10
identifier_str_mv 10.1016/j.meegid.2020.104684
network_acronym_str Manara2
network_name_str Manara2
oai_identifier_str oai:figshare.com:article/24087663
publishDate 2021
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spelling Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two monthsLaith J. Abu-Raddad (9262524)Hiam Chemaitelly (439114)Joel A. Malek (10327973)Ayeda A. Ahmed (11847025)Yasmin A. Mohamoud (10671696)Shameem Younuskunju (6850097)Zaina Al Kanaani (5018198)Abdullatif Al Khal (12024468)Einas Al Kuwari (12024471)Adeel A. Butt (3697705)Peter Coyle (787159)Andrew Jeremijenko (11506565)Anvar Hassan Kaleeckal (11847034)Ali Nizar Latif (11570540)Riyazuddin Mohammad Shaik (11847037)Hanan F. Abdul Rahim (9330201)Hadi M. Yassine (4675846)Mohamed G. Al Kuwari (12024474)Hamad Eid Al Romaihi (12024477)Mohamed H. Al-Thani (11847049)Roberto Bertollini (9538620)Biological sciencesMicrobiologyBiomedical and clinical sciencesClinical sciencesSARS-CoV-2COVID-19EpidemiologyInfectionGenomeInfectious period<p dir="ltr">We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons.</p><h2>Other Information</h2><p dir="ltr">Published in: Infection, Genetics and Evolution<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.meegid.2020.104684" target="_blank">https://dx.doi.org/10.1016/j.meegid.2020.104684</a></p>2021-03-01T00:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.meegid.2020.104684https://figshare.com/articles/journal_contribution/Two_prolonged_viremic_SARS-CoV-2_infections_with_conserved_viral_genome_for_two_months/24087663CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/240876632021-03-01T00:00:00Z
spellingShingle Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
Laith J. Abu-Raddad (9262524)
Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
SARS-CoV-2
COVID-19
Epidemiology
Infection
Genome
Infectious period
status_str publishedVersion
title Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
title_full Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
title_fullStr Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
title_full_unstemmed Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
title_short Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
title_sort Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
topic Biological sciences
Microbiology
Biomedical and clinical sciences
Clinical sciences
SARS-CoV-2
COVID-19
Epidemiology
Infection
Genome
Infectious period