Revisting definition of bronchopulmonwry dysplaisa
<h3>Primary objective</h3> <p>To determine which definition of BPD has better predictability for severe respiratory morbidity at 20-50 month corrected age.</p> <h3>Study design</h3> <p>Prospective cohort study, aiming to evaluate the ability of the current d...
محفوظ في:
| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , |
| منشور في: |
2023
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| الموضوعات: | |
| الوسوم: |
إضافة وسم
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| الملخص: | <h3>Primary objective</h3> <p>To determine which definition of BPD has better predictability for severe respiratory morbidity at 20-50 month corrected age.</p> <h3>Study design</h3> <p>Prospective cohort study, aiming to evaluate the ability of the current definitions of BPD to predict serious respiratory morbidity at 20-50 month corrected age.</p> <h3>Methods</h3> <p>sample included all babies with gestational age < 31 weeks who were diagnosed with BPD , born from Jan 2018 till May 2021. sample size is 348 babies . Babies with major significant congenital anomalies, death before 28 days of life were excluded . Data collection done in two phases , first one for demographic data was extracted from Vermont database , Prospective data was collected using telephone interviews with caregivers. Data arranged in excel sheet , analyzed using SPSS program . We used Chi square for categorical data and T –Test for numerical data .</p> <h3>Results</h3> <p>data included total of 348 babies . Total followup rate is 81.6 % .Yearly followup rate was 62 % , 88% , 85 % and 94 % for babies born in 2018, 2019, 2020, Jan-May 2021 respectively . 53.2 % of our population are males .80% of population gestational age ranged between 24-28 weeks. Chorioamnionitis was present in 9.5 % and 85% received antenatal steroids. Around 70% of babies required intubation during resuscitation . Almost 11 % had LOS . 4.9 % of our babies were discharged on oxygen. Total number of deaths were 19 . 3 of them died after transfer to Sidra hospital and 2 died as a result of cardiac arrest post discharge . BPD cases were divided into 2 groups of mild and Moderate/severe . Moderate / severe BPD cases were 34.8 % ( 122) , 18.5 % (65 ) and 29.3% (103) according to 2001, 2016 and 2019 respectively . Regarding comparison between different definitions, 2001 definition was significant for postnatal steroids use , discharge on home o2 , and > 3 hospital admissions . 2016 definition was significant for postnatal steroids , home o2 , tracheostomy . 2019 was significant for postnatal steroids , home o2 , > 3 hospital admissions.</p> <h3>In conclusion</h3> <p>all three definitions are comparable , however we encourage our institution to agree on one definition . We emphasize on the importance of evidence based medicine in research.</p> |
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