Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework

<h3>Background</h3><p dir="ltr">Only 5–10% of all adverse drug reactions (ADRs) are reported. Mechanisms to support patient and public reporting offer numerous advantages to health care systems including increasing reporting rate. Theory-informed insights into the factors...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Laila Shafei (17045772) (author)
مؤلفون آخرون: Lina Mekki (17785706) (author), Esraa Maklad (17785709) (author), Turfa Alhathal (17785712) (author), Rawan Ghanem (17725980) (author), Rama Almalouf (17785715) (author), Derek Stewart (117849) (author), Zachariah Nazar (8600154) (author)
منشور في: 2023
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author Laila Shafei (17045772)
author2 Lina Mekki (17785706)
Esraa Maklad (17785709)
Turfa Alhathal (17785712)
Rawan Ghanem (17725980)
Rama Almalouf (17785715)
Derek Stewart (117849)
Zachariah Nazar (8600154)
author2_role author
author
author
author
author
author
author
author_facet Laila Shafei (17045772)
Lina Mekki (17785706)
Esraa Maklad (17785709)
Turfa Alhathal (17785712)
Rawan Ghanem (17725980)
Rama Almalouf (17785715)
Derek Stewart (117849)
Zachariah Nazar (8600154)
author_role author
dc.creator.none.fl_str_mv Laila Shafei (17045772)
Lina Mekki (17785706)
Esraa Maklad (17785709)
Turfa Alhathal (17785712)
Rawan Ghanem (17725980)
Rama Almalouf (17785715)
Derek Stewart (117849)
Zachariah Nazar (8600154)
dc.date.none.fl_str_mv 2023-05-29T03:00:00Z
dc.identifier.none.fl_str_mv 10.1007/s11096-023-01591-z
dc.relation.none.fl_str_mv https://figshare.com/articles/journal_contribution/Factors_that_influence_patient_and_public_adverse_drug_reaction_reporting_a_systematic_review_using_the_theoretical_domains_framework/24995729
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Adverse drug reactions
Behaviour change
Direct patient reporting
Drug safety
Pharmacovigilance
Selfreporting
Theoretical domains framework
Under-reporting
dc.title.none.fl_str_mv Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
dc.type.none.fl_str_mv Text
Journal contribution
info:eu-repo/semantics/publishedVersion
text
contribution to journal
description <h3>Background</h3><p dir="ltr">Only 5–10% of all adverse drug reactions (ADRs) are reported. Mechanisms to support patient and public reporting offer numerous advantages to health care systems including increasing reporting rate. Theory-informed insights into the factors implicated in patient and public underreporting are likely to offer valuable opportunity for the development of effective reporting-interventions and optimization of existing systems.</p><h3>Aim</h3><p dir="ltr">To collate, summarize and synthesize the reported behavioral determinants using the theoretical domains framework (TDF), that influence patient and public reporting of ADRs.</p><h3>Method</h3><p dir="ltr">Cochrane, CINAHL, Web of science, EMBASE and PubMed were systematically searched on October 25th, 2021. Studies assessing the factors influencing public or patients reporting of ADRs were included. Full-text screening, data extraction and quality appraisal were performed independently by two authors. Extracted factors were mapped to TDF.</p><h3>Results</h3><p dir="ltr">26 studies were included conducted in 14 countries across five continents. Knowledge, social/professional role and identity, beliefs about consequences, and environmental context and resources, appeared to be the most significant TDF domains that influenced patient and public behaviors regarding ADR reporting.</p><h3>Conclusion</h3><p dir="ltr">Studies included in this review were deemed of low risk of bias and allowed for identification of key behavioural determinants, which may be mapped to evidence-based behavioral change strategies that facilitate intervention development to enhance rates of ADR reporting. Aligning strategies should focus on education, training and further involvement from regulatory bodies and government support to establish mechanisms, which facilitate feedback and follow-ups on submitted reports.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Clinical Pharmacy<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11096-023-01591-z" target="_blank">https://dx.doi.org/10.1007/s11096-023-01591-z</a></p>
eu_rights_str_mv openAccess
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identifier_str_mv 10.1007/s11096-023-01591-z
network_acronym_str Manara2
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oai_identifier_str oai:figshare.com:article/24995729
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spelling Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains frameworkLaila Shafei (17045772)Lina Mekki (17785706)Esraa Maklad (17785709)Turfa Alhathal (17785712)Rawan Ghanem (17725980)Rama Almalouf (17785715)Derek Stewart (117849)Zachariah Nazar (8600154)Biomedical and clinical sciencesPharmacology and pharmaceutical sciencesAdverse drug reactionsBehaviour changeDirect patient reportingDrug safetyPharmacovigilanceSelfreportingTheoretical domains frameworkUnder-reporting<h3>Background</h3><p dir="ltr">Only 5–10% of all adverse drug reactions (ADRs) are reported. Mechanisms to support patient and public reporting offer numerous advantages to health care systems including increasing reporting rate. Theory-informed insights into the factors implicated in patient and public underreporting are likely to offer valuable opportunity for the development of effective reporting-interventions and optimization of existing systems.</p><h3>Aim</h3><p dir="ltr">To collate, summarize and synthesize the reported behavioral determinants using the theoretical domains framework (TDF), that influence patient and public reporting of ADRs.</p><h3>Method</h3><p dir="ltr">Cochrane, CINAHL, Web of science, EMBASE and PubMed were systematically searched on October 25th, 2021. Studies assessing the factors influencing public or patients reporting of ADRs were included. Full-text screening, data extraction and quality appraisal were performed independently by two authors. Extracted factors were mapped to TDF.</p><h3>Results</h3><p dir="ltr">26 studies were included conducted in 14 countries across five continents. Knowledge, social/professional role and identity, beliefs about consequences, and environmental context and resources, appeared to be the most significant TDF domains that influenced patient and public behaviors regarding ADR reporting.</p><h3>Conclusion</h3><p dir="ltr">Studies included in this review were deemed of low risk of bias and allowed for identification of key behavioural determinants, which may be mapped to evidence-based behavioral change strategies that facilitate intervention development to enhance rates of ADR reporting. Aligning strategies should focus on education, training and further involvement from regulatory bodies and government support to establish mechanisms, which facilitate feedback and follow-ups on submitted reports.</p><h2>Other Information</h2><p dir="ltr">Published in: International Journal of Clinical Pharmacy<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11096-023-01591-z" target="_blank">https://dx.doi.org/10.1007/s11096-023-01591-z</a></p>2023-05-29T03:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1007/s11096-023-01591-zhttps://figshare.com/articles/journal_contribution/Factors_that_influence_patient_and_public_adverse_drug_reaction_reporting_a_systematic_review_using_the_theoretical_domains_framework/24995729CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/249957292023-05-29T03:00:00Z
spellingShingle Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
Laila Shafei (17045772)
Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Adverse drug reactions
Behaviour change
Direct patient reporting
Drug safety
Pharmacovigilance
Selfreporting
Theoretical domains framework
Under-reporting
status_str publishedVersion
title Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
title_full Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
title_fullStr Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
title_full_unstemmed Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
title_short Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
title_sort Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
topic Biomedical and clinical sciences
Pharmacology and pharmaceutical sciences
Adverse drug reactions
Behaviour change
Direct patient reporting
Drug safety
Pharmacovigilance
Selfreporting
Theoretical domains framework
Under-reporting